- RIUMA Principal
- Investigación
- Fisiología Humana, Histología Humana, Anatomía Patológica y Educación Física y Deportiva - (FHEFD)
- Listar Fisiología Humana, Histología Humana, Anatomía Patológica y Educación Física y Deportiva - (FHEFD) por autor
Listar Fisiología Humana, Histología Humana, Anatomía Patológica y Educación Física y Deportiva - (FHEFD) por autor "Narváez-Bueno, José Ángel"
Mostrando ítems 21-40 de 46
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Galanin decreases NPYY1R internalization and β- Arrestin2 recruitment
Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderón, Belén; Santín-Núñez, Luis Javier; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2015-10-05)We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers. The aim of this work was to study ... -
Galanin interacts with Neuropeptide Y Y1 receptor in the dentate gyrus of the hippocampus through GALR2/NPYY1R heterodimers
Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderón, Belén; Santín-Núñez, Luis Javier; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2016-07-11)We have shown Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to analyze GAL/NPYY1R interactions ... -
Galanin n-terminal fragment (1-15) decreases the voluntary alcohol intake in rats
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Castilla-Ortega, María Estela; Gago-Calderón, Belén; Serrano, Antonia; Sturla, Antonella; García-Durán, Laura; Narváez-Bueno, José Ángel; Fuxe, Kjell; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2018-06-28)Galanin (GAL) is involved in drug abuse and addiction including alcohol intake. In this work, we have analysed the role of the N-terminal GAL fragment (1-15) [GAL(1-15)] in voluntary ethanol consumption in rats using the ... -
Galanin N-Terminal fragment (1-15) enhances the antidepressant effects of the 5-HT1A receptor agonist 8-OH-DPAT in the Forced Swimming Test.
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Santín-Núñez, Luis Javier; Gago-Calderón, Belén; Parrado-Romero, Concepción; Gomez de Travecedo, Isabel; Narváez-Bueno, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2016-07-27)Galanin and Galanin (1-15) [GAL(1-15)] are implicated in anxiety- and depression related behaviors. Moreover, Galanin modulates 5-HT1A receptor (5-HT1AR) function at autorreceptor and postsynaptic level in the brain. In ... -
Galanin N-Terminal fragment (1-15) induces a stronger effect than Galanin in depression- and anxiety- like related behavioural tests in rats.
Millón-Peñuela, Carmelo; Narváez-Peláez, Manuel; Flores-Burgess, Antonio; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Coveñas, Rafael; Santín-Núñez, Luis Javier; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2014-07-16)Galanin (GAL) and GAL Receptors are implicated in anxiety- and depression- related behaviours. The GAL N-terminal fragment (1-15) [GAL(1-15)] also induces depressant- and anxiogenic- like actions. In this work, we have ... -
Galanin n-terminal fragment (1-15) induces an anxiety- and depressive-like behaviours in the light/dark and tail suspension tests
Flores-Burgess, Antonio; Millón-Peñuela, Carmelo; Narváez-Peláez, Manuel; Santín-Núñez, Luis Javier; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2015-10-21)Galanin N-terminal fragment (1-15) [Gal(1-15)] is involved in mood regulation. We have shown that intracerebroventricular (icv) administration of Gal(1-15) produces a depressive-like behaviour in the forced swim test (FST) ... -
Galanin n-terminal gragment (1-15) modifies the 5-HT1A receptor against [H3]-8-OH-DPAT binding in the dorsal raphe and hippocampus of the rat
Flores-Burgess, Antonio; Millón-Peñuela, Carmelo; Narváez-Peláez, Manuel; Barroto-Escuela, Dasiel; Santín-Núñez, Luis Javier; Gago-Calderón, Belén; Gomez de Travecedo, Isabel; Narváez-Bueno, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2016-09-09)We have described that Galanin N-terminal fragment (1-15) [GAL(1-15)] is associated with depressive effects and also modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist 8-OH-DPAT. The aim ... -
Galanin receptor 2 modifies neuropeptide Y Y1 receptor internalization and β-Arrestin recruitment
Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderón, Belén; Santín-Núñez, Luis Javier; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2015-10-05)We have recently described a Galanin receptor 2(GALR2) and Neuropeptide Y Y1 receptor(NPYY1R) interaction at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers. The aim of this work was to study ... -
Galanin receptor/neuropeptide y recptor interactions in the central nervous system
Díaz-Cabiale, Zaida; Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Borroto Escuela, Dasiel Óscar; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Fuxe, Kjell; Narváez-Bueno, José Ángel[et al.] (2013-11-20)The presence of Galanin and Neuropeptide Y and/or their receptors in many relevant brain regions related to learning and memory, mood, cardiovascular control and food intake implies that Galanin, and Neuropeptide Y may ... -
Galanin(1-15) reverses the impaired long-term memory effect of fluoxetine in the novel object recognition test. Role of 5-HT1A receptor in medial prefrontal cortex
Flores-Burgess, Antonio; Millón-Peñuela, Carmelo; Gago-Calderón, Belén; García-Durán, Laura; Cantero-García, Noelia; Coveñas, Rafael; Narváez-Bueno, José Ángel; Fuxe, Kjell; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2019-12-16)In this work, we have studied the effects of GAL(1-15) on FLX- mediated effects on the NOR and the OLM, two tasks where FLX treatment impaired long-term memories 24h post-training. Since the mPFC is a core region for the ... -
Galanin/ Neuropeptide Y Y1 receptor interaction at the cellular and receptor level in the amygdala
Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Díaz-Cabiale, Zaida; Narváez-Bueno, José Ángel[et al.] (2013-11-18)Galanin (GAL) interacts functionally with Neuropeptide Y Y1 receptor (Y1) in the nucleus tractus solitarius and the arcuate nucleus. Since GAL and Y1 participate in mood disorders, the aim of this work was to analyze GAL/Y1 ... -
GALR1/GALR2 Knockdown rats block the Depression and Anxiogenic effects induced by GAL(1-15): The Heterodimer GALR1/GALR2 as a target of GAL(1-15).
Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Narváez-Bueno, José Ángel; Fuxe, Kjell; Díaz-Cabiale, Zaida[et al.] (2015-10-06)The Galanin N-terminal fragment (1-15) [GAL(1-15)] induces depressant- and anxiogenic- like actions. In this work, we have studied the role of GALR2 and GALR1 on the effects of GAL(1-15) in the Forced Swimming Test (FST) ... -
GALR2/NPYY1R heterodimers interact at receptor level in the dentate gyrus of the hippocampus in rats
Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Gago-Calderón, Belén; Santín-Núñez, Luis Javier; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2016-09-26)Previously, we have described Galanin(GAL) and Neuropeptide Y Y1(NPYY1) interactions at behavioural, cellular and receptor levels through GALR2/NPYY1R heterodimers in the amygdala. The aim of this work was to study GAL/NPYY1R ... -
Graphene oxide and reduced derivates, as powder or film scaffolds, differentially promote dopaminergic neuron differentiation and survival.
Rodríguez-Losada, Noela; Wendelbo, Rune; Ocaña, C; Díaz-Casares, Amelia; Guzmán de Villoria, Roberto; Aguirre-Gómez, José Ángel; Arráez-Sánchez, Miguel Ángel; González-Alegre, P; Medina, MA; Arenas, E; Narváez-Bueno, José Ángel[et al.] (Frontiers, 2020)Emerging scaffold structures made of carbon nanomaterials, such as graphene oxide (GO) have shown efficient bioconjugation with common biomolecules. Previous studies described that GO promotes the differentiation of neural ... -
Immunohistochemical C-FOS expression and autoradiography to study galnin/neuropeptide y Y1 receptor-receptor interactions in the amygdala
Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Puigcerver-Martínez, Araceli; Borroto Escuela, Dasiel Óscar; Fuxe, Kjell; Díaz-Cabiale, Zaida; Narváez-Bueno, José Ángel[et al.] (2013-10-02)We have shown Galanin(GAL)/Neuropeptide Y Y1 receptor(Y1) interactions in the nucleus tractus solitarius and the arcuate nucleus. Since both peptides play an important role in mood disorders, the aim of this work was to ... -
Interacciones entre la Galanina (1-15) y los receptores Serotoninérgicos 5HT1A en el Sistema Nervioso Central: Implicación en la depresión
Millón-Peñuela, Carmelo (Servicio de Publicaciones y Divulgación Científica, 2015)La Galanina (GAL) es un neuropéptido ampliamente distribuido en el Sistema Nervioso Central (SNC), que presenta un fragmento N-terminal de 15 aminoácidos común en todos los mamíferos. La GAL participa en diversas funciones, ... -
New augmentation strategy in depression: Galanin (1-15) enhances the behavioral effects of Fluoxetine in the olfactory bulbectomy rat.
Flores-Burgess, Antonio; Pineda-Gómez, Juan Pedro; Millón-Peñuela, Carmelo; Gago-Calderón, Belén; García-Durán, Laura; Cantero-García, Noelia; Puigcerver-Martínez, Araceli; Narváez-Bueno, José Ángel; Fuxe, Kjell; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida[et al.] (2022-07-12)Major depression is the largest contributor to global disability by years lived with disability. Selective serotonergic reuptake inhibitors, including fluoxetine (FLX), are the most commonly used antidepressant for the ... -
NPYY1 /Galanin 2 heterodimers in the amygdala: a proximity ligation assay study
Narváez-Peláez, Manuel; Millón-Peñuela, Carmelo; Borroto Escuela, Dasiel Óscar; Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Parrado-Romero, Concepción; Gago-Calderón, Belén; Puigcerver-Martínez, Araceli; Fuxe, Kjell; Narváez-Bueno, José Ángel; Díaz-Cabiale, Zaida[et al.] (2014-07-10)We have shown that Galanin(GAL) interacts with Neuropeptide Y Y1 receptor(Y1) at behavioural, cellular and receptor levels in the Amygdala. Since both peptides play an important role in mood disorders, the aim of this work ... -
Role of the 5-HT1A receptors in the effect of Galanin(1-15) on Fluoxetine-mediated action in the forced swimming test
Flores-Burgess, Antonio; Santín-Núñez, Luis Javier; Díaz-Cabiale, Zaida; Millón-Peñuela, Carmelo; Narváez-Peláez, Manuel; Borroto Escuela, Dasiel Óscar; Narváez-Bueno, José Ángel; Fuxe, Kjell[et al.] (2018-06-28)Galanin N-terminal fragment (1-15) [GAL(1-15)] modulates the antidepressant effects induced by the 5-HT1A receptor (5-HT1AR) agonist in the forced swimming test (FST) and the binding characteristics and mRNA levels of ...