Listar FHEFD - Artículos por fecha de publicación
Mostrando ítems 1-20 de 134
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Laryngeal effects of stimulation of rostral and ventral pons in the anaesthetized rat
Lara-Muñoz, José Pablo
; Dawid-Milner, Marc Stefan; López-González, Manuel Víctor; Montes, Carmen; Spyer, KM; González-Barón, Salvador[et al.] (Elsevier, 2002)
In order to study the importance of two pontine regions modulating laryngeal resistance, electrical current or microinjections of glutamate (10–30 nl, 1–3 nmol) were made into the pontine parabrachial complex and the A5 ... -
A5 region modulation of the cardiorespiratory responses evoked from parabrachial cell bodies in the anaesthetised rat
Dawid-Milner, Marc Stefan; Lara-Muñoz, José Pablo; López de Miguel, M Pilar; López-González, Manuel Víctor; Spyer, KM; González-Barón, Salvador[et al.] (Elsevier, 2003)
We have examined the importance of the A5 region modulating cardiorespiratory responses evoked from the parabrachial complex (PB) in spontaneously breathing rats. Cardiorespiratory changes were analyzed in response to ... -
Semaphorin5A expression in the developing chick telencephalon.
Pineda Tenor, Daniel; Garcia Diaz, Beatriz; Olmos, José Luis; Dávila-Cansino, José Carlos; Real-Avilés, María Ángeles; Guirado-Hidalgo, Salvador[et al.] (Elsevier, 2005)
In the present study, we analyzed the expression of Semaphorin5A (Sema5A), a gene implicated in axon guidance and many other processes of neuronal development, in the developing chick telencephalon. By using a heterologous ... -
Autologous Human-Derived Bone Marrow Cells Exposed to a Novel TGF-β1 Fusion Protein for the Treatment of Critically Sized Tibial Defect.
Becerra-Ratia, José; Guerado-Parra, Enrique; Claros-Gil, Silvia; Alonso, Mónica; Bertrand, María L; González Plata, Carlos; Andrades-Gómez, José Antonio[et al.] (Taylor & Francis, 2006)
We report the first clinical case of transplantation of autologous bone marrow-derived cells in vitro exposed to a novel recombinant human transforming growth factor (rhTGF)-β1 fusion protein bearing a collagen-binding ... -
Enhanced markers of oxidative stress, altered antioxidants and NADPH-oxidase activation in brains from Fragile X mental retardation 1-deficient mice, a pathological model for Fragile X syndrome.
El-Bekay, Rajaa; Romero-Zerbo, Silvana Yanina; Decara, Juan; Sánchez-Salido, Lourdes; Del Arco-Herrera, Ignacio; Rodriguez-de-Fonseca, Fernando; De Diego‑Otero, Yolanda[et al.] (Wiley, 2007)
Fragile X syndrome is the most common form of inherited mental retardation in humans. It originates from the loss of expression ofthe Fragile X mental retardation 1 (FMR1) gene, which results in the absence of the Fragile ... -
Deletion of lysophosphatidic acid receptor LPA1 reduces neurogenesis in the mouse dentate gyrus
Matas-Rico, Elisa; Garcia Diaz, Beatriz; Llebrez Zayas, Pedro; López-Barroso, Diana; Santín-Núñez, Luis Javier; Pedraza-Benítez, María del Carmen; Smith-Fernández, José Aníbal; Téllez-Santana, Teresa; Redondo-Bautista, Maximino; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Estivill-Torrús, Guillermo[et al.] (Elsevier, 2008)
Neurogenesis persists in certain regions of the adult brain including the subgranular zone of the hippocampal dentate gyrus wherein its regulation is essential, particularly in relation to learning, stress and modulation ... -
The effect of type I collagen on osteochondrogenic differentiation in adipose-derived stromal cells in vivo.
Alonso, Mónica; Claros-Gil, Silvia; Becerra-Ratia, José; Andrades-Gómez, José Antonio (Elsevier, 2008)
Background The objective of this study was to investigate whether type I collagen would elicit in vivo bone formation of passaged rat adipose-derived adult stromal cells (ADASC) placed extraskeletally. Methods After ... -
Selection and induction of rat skeletal muscle-derived cells to the chondro-osteogenic lineage.
Claros-Gil, Silvia; Alonso, Mónica; Becerra-Ratia, José; Andrades-Gómez, José Antonio (CMB Association, 2008-10-26)
Bone marrow (BM) has been long established as the main source of pluripotential mesenchymal stem cells (MSCs), and has been so far the main recognized source of osteoprogenitor cells that ... -
Role of the parabrachial complex in the cardiorespiratory response evoked from hypothalamic defense area stimulation in the anesthetized rat
Díaz-Casares, Amelia; López-González, Manuel Víctor; Peinado-Aragonés, Carlos Antonio; González Barón, Salvador; Dawid-Milner, Marc Stefan (Elsevier, 2009)
To analyze the role of parabrachial complex (PBc) in the modulation of cardiorespiratory response evoked from the hypothalamic defense area (HDA), cardiorespiratory changes were analyzed in spontaneously breathing anesthetised ... -
Overexpression of Cannabinoid CB2 Receptor in the Brain Induces Hyperglycaemia and a Lean Phenotype in Adult Mice
Romero-Zerbo, Silvana Yanina; Garcia-Gutierrez, M S; Suárez-Pérez, Juan; Rivera, Patricia; Ruz-Maldonado, Inmaculada; Vida, M.; Rodriguez-de-Fonseca, Fernando; Manzanares, Jorge; Bermúdez Silva, Francisco Javier[et al.] (Blackwell Publishing Ltd, 2009)
t is well known that the endocannabinoid system, through cannabinoid CB1 receptor activation,has an important role in the main aspects of energy balance (i.e. food intake, energy expenditureand glucose and fat metabolism), ... -
Protective effects of melatonin against oxidative stress in Fmr1 knockout mice: a therapeutic research model for the fragile X syndrome
Romero-Zerbo, Silvana Yanina; Decara, Juan; El Bekay Rizky, Rajaa; Sánchez-Salido, Lourdes; Del Arco-Herrera, Ignacio; Rodriguez-de-Fonseca, Fernando; De-Diego-Otero, María Yolanda[et al.] (Blackwell Munksgaard, 2009)
Fragile X syndrome is the most common form of inherited mentalretardation. It is typically caused by a mutation of the Fragile X mental-retardation 1 (Fmr1) gene. To better understand the role of the Fmr1 geneand its gene ... -
Early maternal deprivation induces gender-dependent changes on the expression of hippocampal CB(1) and CB(2) cannabinoid receptors of neonatal rats.
Suárez-Pérez, Juan; Llorente, Ricardo; Romero-Zerbo, Silvana Yanina; Mateos, Beatriz; Bermúdez Silva, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Paz Viveros, Maria; Suárez-Pérez, Juan[et al.] (Wiley, 2009)
Early maternal deprivation (MD) in rats (24 h, postnatal day 9–10) is a model for neurodevelopmental stress. There are some data proving that MD affects the endocannabinoid system (ECS) in a gender-dependent manner, and ... -
Alpha-tocopherol protects against oxidative stress in the fragile X knockout mouse: an experimental therapeutic approach for the Fmr1 deficiency.
De Diego‑Otero, Yolanda; Romero-Zerbo, Silvana Yanina; El-Bekay, Rajaa; Decara, Juan; Sánchez-Salido, Lourdes; Rodriguez-de-Fonseca, Fernando; Del Arco-Herrera, Ignacio[et al.] (Springer Nature, 2009)
Fragile X syndrome is the most common genetic cause of mental disability. The mechanisms underlying the pathogenesis remain unclear and specific treatments are still under development. Previous studies have proposed an ... -
Cellular aging: theories and technological influence
Mercado-Sáenz, Silvia; Ruiz-Gómez, Miguel José; Morales-Moreno, Francisco; Martínez Morillo, Manuel (Scielo Brazil, 2010-12-02)
The aim of this article was to review the factors that influence the aging, relationship of aging with the biological rhythms and new technologies as well as the main theories to explain the aging, and to analysis the ... -
Reduction of body weight, liver steatosis and expression of stearoyl-CoA desaturase 1 by the isoflavone daidzein in diet-induced obesity.
(Wiley, 2011)Background and purpose. The lack of safe and effective approved drugs against obesity has raised a great interest on natural products that may serve as alternative therapies. From this perspective we have addressed the ... -
Parabrachial complex glutamate receptors modulate the cardiorespiratory response evoked from hypothalamic defense area
Díaz-Casares, Amelia; López-González, Manuel Víctor; Peinado-Aragonés, Carlos Antonio; González-Barón, Salvador; Dawid-Milner, Marc Stefan (Elsevier, 2012)
To characterize the possible role of glutamate in the interaction between Hypothalamic Defense Area (HDA) and Parabrachial complex (PBc) nuclei, cardiorespiratory changes were analyzed in response to electrical stimulation ... -
Ulcerative colitis impairs the acylethanolamide-based anti-inflammatory system reversal by 5-aminosalicylic acid and glucocorticoids.
Suárez-Pérez, Juan; Romero-Zerbo, Silvana Yanina; Márquez, Lucia; Rivera, Patricia; Iglesias, Mar; Bermúdez Silva, Francisco Javier; Andreu, Montserrat; Rodriguez-de-Fonseca, Fernando[et al.] (PLOS, 2012)
Studies in animal models and humans suggest anti-inflammatory roles on the N-acylethanolamide (NAE)-peroxisome proliferators activated receptor alpha (PPARα) system in inflammatory bowel diseases. However, the presence and ... -
Infantile Encephaloneuromyopathy and Defective Mitochondrial Translation Are Due to a Homozygous RMND1 Mutation
(The American Society of Human Genetics, 2012)Defects of mitochondrial protein synthesis are clinically and genetically heterogeneous. We previously described a male infant who was born to consanguineous parents and who presented with severe congenital encephalopathy, ... -
The role of the endocannabinoid system in eating disorders: pharmacological implications
Marco, Eva-María; Romero-Zerbo, Silvana Yanina; Paz Viveros, María; Bermúdez Silva, Francisco Javier (Wolters Kluwer Health, 2012)
The endocannabinoid (eCB) system is a widespread intercellular signalling mechanism that plays a critical role in body homoeostasis. It is located in key points involved in food intake and energy expenditure, coordinating ... -
Induction of superficial zone protein (SZP)/ lubricin/PRG 4 in muscle-derived mesenchymal stem/progenitor cells by transforming growth factor-b1 and bone morphogenetic protein-7
Andrades-Gómez, José Antonio; Motaung, Shirley C; Jiménez-Palomo, Pedro; Claros-Gil, Silvia; López-Puerta, José M.; Becerra-Ratia, José; Schmid, Thomas M.; Reddi, A. Hari[et al.] (Springer Nature, 2012-04-10)
Introduction Articular cartilage (AC) is an avascular tissue with precise polarity and organization. The three distinct zones are: surface, middle and deep. The production and accumulation of the superficial zone protein ...