Listar MD - Artículos por autor "Torres-Jaén, María Josefa"
Mostrando ítems 1-12 de 12
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Advances and highlights in T and B cell responses to drug antigens
Fernández-Santamaría, Rubén; Ariza Veguillas, Adriana; Fernández-Duarte, Tahía Diana; Céspedes Lagos, José Antonio; Labella, Marina; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-07)The immunological mechanisms involved in drug hypersensitivity reactions (DHRs) are complex, and despite important advances, multiple aspects remain poorly understood. These not fully known aspects are mainly related to ... -
Allergen exposure boosts peripheral Th9 responses in patients with local allergic rhinitis
Palomares, Francisca; Aranda, Carlos José; Saenz de Santa María-García, Rocío; Mayorga Mayorga, Cristobalina; Rondón Segovia, Carmen; Testera Montes, Almudena; Alba-Linero, Carmen; Bentabol-Ramos, Guillermo; Torres-Jaén, María Josefa; Eguiluz-Gracia, Ibón[et al.] (Wiley, 2023)Key points ∙ Intranasal allergen exposure increases peripheral total Th2 and Th9 cells in patients with local allergic rhinitis (LAR). ∙ Peripheral T-cell response seems dominated by Th9 cells in patients with LAR, ... -
Basophil Activation Test Utility as a Diagnostic Tool in LTP Allergy
Cañas, José Antonio; Pérez-Sánchez, Natalia Isabel; Palomares, Francisca; Molina, Ana; Bartra, Joan; Torres-Jaén, María Josefa; Gómez, Francisca; Mayorga Mayorga, Cristobalina[et al.] (IOAP-MPDI, 2022-04-29)Plant-food allergy is an increasing problem, with nonspecific lipid transfer proteins (nsLTPs) triggering mild/severe reactions. Pru p 3 is the major sensitizer in LTP food allergy (FA). However, in vivo and in vitro ... -
Biomarkers predicting the controller dose of omalizumab in patients with chronic spontaneous urticaria
Zubiaga- Fernandez, L.; Testera Montes, Almudena; Rondon, C.; Perez-Sanchez, N.; Gomez- Perez, F.; Vega-Chicote, J. M.; Bartra, Joan; Ferrer, M.; Eguiluz-Gracia, Ibón; Torres-Jaén, María Josefa[et al.] (Wiley, 2024-02-11)Background Clinical trials showed the efficacy of 300 mg/4 weeks of omalizumab (OMA) during 6 months in patients with severe chronic spontaneous urticaria (CSU). Nevertheless, in real life, many patients require higher ... -
Changing patterns in the epidemiology of drug allergy
Doña, Inmaculada; Torres-Jaén, María Josefa; Gulfem, Celik; Phillips, Elizabeth; Kase Tanno, Luciana; Castells, Mariana[et al.] (Wiley, 2023-12-12)Drug allergy (DA) remains a complex and unaddressed problem worldwide that often deprives patients of optimal medication choices and places them at risk for life-threatening reactions. Underdiagnosis and overdiagnosis are ... -
Detection of Serum-Specific IgE by Fluoro-Enzyme Immunoassay for Diagnosing Type I Hypersensitivity Reactions to Penicillins
Ariza Veguillas, Adriana; Mayorga Mayorga, Cristobalina; Bogas Herrera, Gádor; Gaeta, Francesco; Salas, María; Valluzzi, Rocco Luigi; Labella, Marina; Pérez-Sánchez, Natalia Isabel; Caruso, Cristiano; Molina, Ana; Fernández-Duarte, Tahía Diana; Torres-Jaén, María Josefa; Romano, Antonino[et al.] (IOAP-MPDI, 2022-06-23)Diagnosis of type I hypersensitivity reactions (IgE-mediated reactions) to penicillins is based on clinical history, skin tests (STs), and drug provocation tests (DPTs). Among in vitro complementary tests, the fluoro-enzyme ... -
Diagnosis and Treatment in Asthma and Allergic Rhinitis: Past, Present, and Future
Espada-Sánchez, Marta; Saenz de Santa María-García, Rocío; Martín Astorga, María del Carmen; Lebrón-Martín, Clara; Romero-Delgado, María-Jesús; Eguiluz-Gracia, Ibón; Rondón Segovia, Carmen; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Aranda, Carlos José; Cañas, José Antonio[et al.] (IOAP-MDPI, 2023-01-18)Respiratory diseases are pathological conditions that affect airways, hampering breathing and causing high mortality. In particular, asthma and allergic rhinitis (AR) are two of the most common airway diseases that affect ... -
Genomic variants association with selective hypersensitivityreactions to amoxicillin and clavulanic acid
Nuñez, Rafael; Fernández-Santamaría, Rubén; Salas, María; Bogas, Gador; Diez-Echave, Patricia; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa; Fernández-Duarte, Tahía Diana[et al.] (Wiley, 2024-06-29)In summary, there are rare variants found in our patients that could be related to the development of AX or CLV- induced IDHRs. Interestingly, some of these rare variants could be associated with selective response to ... -
Medical algorithm: Diagnosis and treatment of nonsteroidal antiinflammatory drugs hypersensitivity
Doña, Inmaculada; Pérez-Sánchez, Natalia; Bogas, Gador; Moreno, Esther; Salas, María; Torres-Jaén, María Josefa[et al.] (Wiley, 2020)Diagnosis in suspected hypersensitivity reactions to nonsteroidal anti-inflammatory drugs (NSAIDs) is complex as different mechanisms are involved: specific (selective responders, SRs) and nonspecific immunologically ... -
Resensitization in suspected penicillin allergy
Doña, Inmaculada; Guidolin, Lucia; Bogas Herrera, Gádor; Olivieri, Elisa; Labella, Marina; Schiapolli, Michele; Saenz de Santa María-García, Rocío; Dama, Annarita; Salas, María; Senna, Gianenrico; Bonadonna, Patrizia; Torres-Jaén, María Josefa[et al.] (Wiley, 2022-09-06)The diagnosis of allergic reactions to penicillins (AR-PEN) is very complex as there is a loss of sensitization over time, which leads to negative skin tests (STs) and specific IgE in serum, and even to tolerance to the ... -
The value of the basophil activation test in the evaluation of patients reporting allergic reactions to the BNT162b2 mRNA COVID-19 vaccine
Labella, Marina; Céspedes Lagos, José Antonio; Doña, Inmaculada; Shamji, Mohamed H.; Agache, Ioana; Mayorga Mayorga, Cristobalina; Torres-Jaén, María Josefa[et al.] (Wiley, 2021-10-24) -
Working with companies that manufacture breastmilk substitutes: An EAACI position paper
Arasi, Stefania; Caubet, J.C.; Ceylan, Ozlem; Ibon Eguíluz, Gracia; Giacco, Stefano Del; Gelincik, Asli; Jute, Marek; Rosan, Meyer; Ollert, Markus; Torres-Jaén, María Josefa[et al.] (Wiley, 2024-05)Breastmilk is the optimal source of nutrition for infants and should ideally be provided exclusively for the first 6 months of life, and alongside complementary food until 2 years of life. However, there are circumstances ...