Listar MD - Artículos por fecha de publicación
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Assessment of Procalcitonin as a Diagnostic and Prognostic Marker in Patients with Solid Tumors and Febrile Neutropenia
(Wiley InterScience, 2004-03)Cancer patients with fever and neutropenia currently are assessed on clinical grounds only. The current study prospectively evaluated the efficacy of baseline procalcitonin (PCT) in the detection of bacteremia and in the ... -
A Carboxylesterase 2 Gene Polymorphism as Predictor of Capecitabine on Response and Time to Progression
(Bentham Science Publishers Ltd, 2008)Capecitabine is a drug that requires the consecutive action of three enzymes: carboxylesterase 2 (CES 2), cytidine deaminase (CDD), and thymidine phosphorylase (TP) for transformation into 5-fluorouracil (5FU). The ... -
Lack of evidence for KRAS oncogenic mutations in triple-negative breast cancer.
(Springer Nature, 2010-04-13)Background: Mutational analysis of the KRAS gene has recently been established as a complementary in vitro diagnostic tool for the identification of patients with colorectal cancer who will not benefit from anti-epidermal ... -
Bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer
(KARGER, 2010-11)Aim: To retrospectively assess the efficacy and safety of bevacizumab plus low-dose metronomic oral cyclophosphamide in heavily pretreated patients with recurrent ovarian cancer. Patients and Methods: Patients with recurrent ... -
Risk-Adapted Treatment in Clinical Stage I Testicular Seminoma: The Third Spanish Germ Cell Cancer Group Study
(Editorial Roster. ASCO publications, 2011-10)Purpose To confirm the efficacy of a risk-adapted treatment approach for patients with clinical stage I seminoma. The aim was to reduce both the risk of relapse and the proportion of patients receiving adjuvant chemotherapy ... -
Targeted therapies in the treatment of germ cell tumors: The need for new approaches against “orphan” tumors
(Elsevier Ireland Ltd, 2012)Germ cell tumors (GCTs) are a heterogeneous group of tumors that are highly clinically relevant to oncologists. GCTs are generally highly sensitive to cisplatin-based chemotherapy and represent a model for curable neoplasms. ... -
Prospective transGEICAM study of the impact of the 21-gene Recurrence Score assay and traditional clinicopathological factors on adjuvant clinical decision making in women with estrogen receptor-positive (ER1) node-negative breast cancer
(Elsevier, 2012-03)This study examined the impact of the Recurrence Score (RS) in Spanish breast cancer patients and explored the associations between clinicopathological markers and likelihood of change in treatment recommendations. Patients ... -
Serum protein levels following surgery in breast cancer patients: A protein microarray approach
(Spandidos Publications, 2012-07)Surgery is the primary treatment for non-metastatic breast cancer. However, the risk of early recurrence remains after surgical removal of the primary tumor. Recurrence is suggested to result from hidden micrometastatic ... -
A randomized phase II trial of platinum salts in basal-like breast cancer patients in the neoadjuvant setting. Results from the GEICAM/2006-03, multicenter study
(Springer, 2012-10)Abstract Chemotherapy remains as the only systemic treatment option available for basal-like breast cancer (BC) patients. Preclinical models and several phase II studies suggested that platinum salts are active drugs in ... -
Mechanisms of photoaging and cutaneous photocarcinogenesis and prospective strategies with phytochemicals
(MDPI, 2015-03-26)Photoaging and photocarcinogenesis are primarily due to solar ultraviolet (UV) radiation, which alters DNA, cellular antioxidant balance, signal transduction pathways, immunology, and the extracellular matrix (ECM). The ... -
Male breast cancer: correlation between immunohistochemical subtyping and PAM50 intrinsic subtypes, and the subsequent clinical outcomes.
(Elsevier, 2017-09-22)Male breast cancer is a rare disease that is still poorly understood. It is mainly classified by immunohistochemistry as a luminal disease. In this study, we assess for the first time the correlation between molecular ... -
Sunscreens effectiveness are not altered by concomitant use of moisturizing creams: An ultraviolet reflectance photography study
(Willey, 2021)Background: Sunscreens are widely used to protect the skin against the harmful effects of solar radiation. It is not known whether solar protection factor of a sunscreen is altered by the concomitant use of other cosmetic ... -
Sun exposure and protection habits in transplant athletes: an international survey
(Willey, 2021)Background: Transplant recipients are particularly prone to the development of skin cancer, and overexposure to UV radiation during outdoor activities increases the risk of carcinogenesis. Objective: The aim of this study ... -
Validity and reliability of the Spanish fear-avoidance components scale in breast cancer survivors
(Wiley, 2021-08-23)Objective:The aim of this study was to carry out a psychometric analysis of theFear-Avoidance Components Scale (FACS-Sp) in Spanish breast cancer survivors(BCS).Methods:A validation study was carried out in 154 BCS. ... -
Relationship between malnutrition and the presence of symptoms of anxiety and depression in hospitalized cancer patients
(Springer, 2021-09-21)Background Anxiety and depression are a common issue in patients with cancer, yet understudied among hospitalized patients. The aim of this study was to estimate the prevalence of anxiety and depression symptomatology in ... -
Advances and highlights in T and B cell responses to drug antigens
(Wiley, 2021-10-07)The immunological mechanisms involved in drug hypersensitivity reactions (DHRs) are complex, and despite important advances, multiple aspects remain poorly understood. These not fully known aspects are mainly related to ... -
The potential role of UV and blue light from the sun, artificial lighting, and electronic devices in melanogenesis and oxidative stress
(Elsevier, 2022)Our exposure to blue light from artificial sources such as indoor lights (mainly light-emitting diodes [LEDs]) and electronic devices (e.g., smartphones, computer monitors, and television screens), has increased in recent ... -
Analysis and evaluation of the operational characteristics of a new photodynamic therapy device
(Elsevier, 2022)One of the key aspects of photodynamic therapy is the light source that is used to irradiate the lesion to be treated. The devices used must ensure that their emission spectrum matches the absorption spectrum of the ... -
Postprandial Hyperlipidemia: Association with Inflammation and Subclinical Atherosclerosis in Patients with Rheumatoid Arthritis
(IOAP-MDPI, 2022-01-08)Objective: To describe postprandial lipidemia in patients with rheumatoid arthritis (RA) and to analyze its association with subclinical atherosclerosis and inflammatory activity. Methods: Observational study of 80 cases ...