• The infralimbic cortex and the hippocampal CA1-Subiculum are functionally involved in the extinction of cocaine-context associationes in mice. 

  Pérez Berlanga, José Manuel; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Mullor-Vigo, Rosa María; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2023)

  Cocaine abuse is a health and social problem worldwide. Treatment seeking for cocaine use disorder is on the rise, and relapse prevention remains as a primary goal. Interventions based on extinction of cocaine-related ...

• Pharmacogenetic inhibition of the infralimbic cortex promotes reinstatement of cocaine-context memories in mice. 

  Pérez-Cano, Ana María; Ávila-Gámiz, Fabiola; Pérez Berlanga, José Manuel; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David (2023)

  Relapse is one of the main problems concerning treatment of cocaine use disorder. It have been suggested that the infralimbic cortex (IL), a division of the medial prefrontal cortex, is involved in extinction and reinstatement ...

• Mild juvenile stress increases resilience to the development of anxious behaviors and prevents neurogenic reduction after stress exposure in adulthood. 

  Chaves-Peña, Patricia; Infantes-López, M. Inmaculada; Nieto-Quero, Andrea; Zambrana-Infantes, Emma; Muñoz-Martín, José; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen[et al.] (2023)

  Stress, especially during sensitive periods of development, can induce neuroplastic changes in brain regions such as the hippocampus, which increases vulnerability to the negative effects of a second stressor during ...

• Impact of a cocoa-based diet rich in polyphenols on cognitive function, emotional behavior, and adult hippocampal neurogenesis in mice. 

  Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Razola-Díaz, María del Carmen; Palma-Morales, Marta; Rivera-González, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela[et al.] (2023)

  Cocoa consumption has long been associated with numerous health benefits due to its rich composition of minerals, fiber, methylxanthines, and polyphenols, particularly flavanols. However, the cognitive effects of cocoa ...

• Experiencia de uso de un cómic (“Arrugas”) como material didáctico en el aula universitaria. 

  García Borrego, Raúl; Requena-Ocaña, Nerea; Mañas Padilla, María del Carmen; Castro Zavala, Adriana; Araos Gómez, Pedro Fernando; Gil-Rodriguez, Sara; Caramés-Tejedor, José María; Ortega-Acosta, Sergio; Edelkraut, Lisa; Rivas-Herencia, Eugenio; Castilla-Ortega, María Estela[et al.] (2023)

  En la actualidad, existen pocas experiencias docentes que incorporen el cómic al entorno universitario. En este trabajo hemos explorado la utilidad de un cómic (“Arrugas”, de Paco Roca) para mejorar el proceso de ...

• Aprendizaje constructivista y capacidades neuropsicológicas prefrontales. 

  Romero-Castillo, Jorge (2023)

  Las actividades docentes innovadoras siguen los postulados del constructivismo y están diseñadas para aumentar la autonomía del alumnado, aunque su función podría ampliarse. Este multidisciplinar trabajo teórico de ...

• The Role of Social Media as a Resource for Mental Health Care. 

  Herrera-Peco, Iván; Fernández-Quijano, Invención; Ruiz-Núñez, Carlos (MDPI, 2023-06-10)

• Exploring the nutritional composition and bioactive compounds in different cocoa powders 

  Razola-Díaz, María del Carmen; Aznar-Ramos, María José; Verardo, Vito; Melgar-Locatelli, Sonia; Castilla-Ortega, María Estela; Rodríguez-Pérez, Celia[et al.] (MDPI, 2023-03-14)

  Cocoa, the main derivative of the seeds of Theobroma cacao L., has been recognized to have several effects on human health including antioxidant and neuro- and cardio-protective effects, among others. These effects have ...

• Temozolomide treatment inhibits spontaneous motivation for exploring a complex object in mice: a potential role of adult hippocampal neurogenesis in ‘curiosity’. 

  Mañas Padilla, María del Carmen; Melgar-Locatelli, Sonia; Vicente, Lucía; Gil-Rodriguez, Sara; Rivera, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela[et al.] (Wiley, 2022-12-14)

  Intrinsic exploratory biases are an innate motivation for exploring certain types of stimuli or environments over others, and they may be associated with cognitive, emotional, and even personality-like traits. However, ...

• Optimal scheduling of ancillary services provided by an electric vehicle aggregator 

  De-la-Torre-Fazio, Sebastián Bienvenido; Aguado-Sánchez, José Antonio; Sauma, E. (Elsevier, 2022-11-21)

  Massification of Electric vehicles (EVs) is becoming a worldwide reality as a means to combat climate change and local pollution. Considering that most of the time vehicles are in parking places, there is an opportunity ...

• Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study 

  Berthier-Torres, Marcelo Luis; Edelkraut, Lisa; López-González, Francisco Javier; López-Barroso, Diana; Mohr, Bettina; Pulvermüller, Friedemann; Starkstein, Sergio E.; Jorge, Ricardo E.; Torres-Prioris, María José; Dávila-Arias, María Guadalupe[et al.] (Elsevier, 2022-12-07)

  This study explored the feasibility and effectiveness of a short-term (10-week) intervention trial using Donepezil administered alone and combined with intensive language action therapy (ILAT) for the treatment of apathy ...

• Environmental enrichment alleviates cognitive and psychomotor alterations and increases adult hippocampal neurogenesis in cocaine withdrawn mice 

  Mañas Padilla, María del Carmen; Tezanos, Patricia; Cintado, Elisa; Vicente, Lucía; Sánchez-Salido, Lourdes; Gil-Rodriguez, Sara; Trejo-Pérez, José Luis; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (Wiley, 2022-11-16)

  Cocaine is a widely used psychostimulant drug whose repeated exposure induces persistent cognitive/emotional dysregulation, which could be a predictor of relapse in users. However, there is scarce evidence on effective ...

• La respuesta placebo en el consumo de cocaína: una revisión sistemática 

  Rueda, Estela; Navarro-Humanes, José Francisco (Elsevier, 2022-11-17)

  El estudio de la respuesta placebo en la modulación de los efectos de las drogas de abuso está recibiendo un interés creciente. El objetivo de la presente revisión sistemática es examinar la respuesta placebo en el consumo ...

• Patients with Schizophrenia Showed Worse Cognitive Performance than Bipolar and Major Depressive Disorder in a Sample with Comorbid Substance Use Disorders 

  Marquez-Arrico, Julia E.; Gonzalez-Sanchez, Alvaro; Navarro-Humanes, José Francisco; Penadés, Rafael; Adan-Puig, Ana (IOAP-MPDI, 2022-11-09)

  Comorbidity of substance use disorders (SUD) and severe mental illness (SMI) is highly frequent in patients, the most common diagnoses being schizophrenia (SZ), bipolar disorder (BD) and major depressive disorder (MDD). ...

• Efectos del estrés sobre comportamientos de tipo depresivo, la microglía y la neurogénesis hipocampal. Papel del sistema LPA endógeno 

  Nieto Quero, Andrea (UMA Editorial, 2022)

  El estrés constituye el principal factor ambiental en la etiología de los trastornos psicopatológicos, entre ellos la depresión. El hipocampo es una de las regiones más sensibles a los efectos nocivos del estrés, pudiendo ...

• Reduction of adult neurogenesis by temozolomide inhibits intrinsic preference for exploring complex objects in mice 

  Melgar-Locatelli, Sonia; Mañas Padilla, María del Carmen; Gil-Rodriguez, Sara; Vicente, Lucía; Gálvez-Callejón, Ana Mar; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela[et al.] (2022)

  Intrinsic exploratory bias is an innate tendency to prefer certain types of stimuli or environments over others. For example, mice would genuinely spent more time exploring perceptually complex objects (i.e. with edges and ...

• Efficacy Of Intensive Tele-Rehabilitation Combined With Donepezil Compared To Face-to-face Administration 

  Gómez Pérez, África Yolanda; Torres-Prioris, María José; Melgar Mota, Ana; Hohl, Ariane; Gutiérrez Cordero, Ismael; Ariza-Corbo, María José; Ortega Palacios, Ricardo; Alfaro Rubio, Francisco; Edelkraut, Lisa; Berthier-Torres, Marcelo Luis; Dávila-Arias, María Guadalupe[et al.] (2022)

  Objectives: (a) To evaluate the benefits promoted by two modalities of intensive language-action therapy, telerehabilitation (Tele-ILAT) and face-to-face (ILAT), applied alone and in combination with Donepezil to persons ...

• Acute psychological stress: effects on hippocampal neurogenesis and the role of microglia 

  Nieto-Quero, Andrea; Chaves-Peña, Patricia; Infantes-López, M. Inmaculada; Zambrana-Infantes, Emma; Tabbai-Amal, Sara; Muñoz-Martin, José; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen[et al.] (2022)

  Among all the factors that can contribute to the onset of psychopathological disorders, stress is the main environmental factor. The hippocampus is one of the most sensitive regions to the harmful effects of stress, in ...

• Effects of sequential exposure to physical exercise and cognitive training on hippocampal neurogenesis in mice 

  Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Mullor-Vigo, Rosa; Perez-Berlanga, José Manuel; Zambrana-Infantes, Emma; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2022-07-13)

  AIMS: Physical exercise and cognitive training hippocampal dependent tasks are known to enhance adult hippocampal neurogenesis (AHN). Here we aimed to evaluate the effect of either a moderate-intensity exercise protocol, ...

• Neuroprotective effects of insulin-like growth factor II in a mouse model of Parkinson's disease 

  Ladrón de Guevara-Miranda, David; Martin-Montañez, Elisa; Valverde, Nadia; Lara, Estrella; Romero Zerbo, Silvana Yanina; Millón-Peñuela, Carmelo; Boraldi, Federica; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Garrido-Gil, Pablo; Labandeira-García, José Luis; Santín-Núñez, Luis Javier; Pavía-Molina, José; García-Fernández, María Inmaculada[et al.] (2022-07-20)

  Progressive degeneration of the nigrostriatal dopaminergic pathway is a core, currently irreversible pathological hallmark of Parkinson’s disease (PD) that leads to a variety of motor and non-motor symptoms. Here, we aimed ...

Más