Listar PMCC - Artículos por autor "Serrano, Antonia"
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Cocaine-conditioned place preference is predicted by previous anxiety-like behavior and is related to an increased number of neurons in the basolateral amygdala
(Elsevier, 2016-02-01)The identification of behavioral traits that could predict an individual's susceptibility to engage in cocaine addiction is relevant for understanding and preventing this disorder, but investigations of cocaine addicts ... -
Lysophosphatidic acid-induced increase in adult hippocampal neurogenesis facilitates the forgetting of cocaine-contextual memory
Ladrón de Guevara-Miranda, David; Moreno-Fernández, Román D.; Gil Rodríguez, Sara; Rosell-del-Valle, Cristina; Estivill-Torrús, Guillermo; Serrano, Antonia; Pavón-Morón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier
; Castilla-Ortega, María Estela[et al.] (Wiley, 2019)
Erasing memories of cocaine-stimuli associations might have important clinical implications for addiction therapy. Stimulating hippocampal plasticity by enhancing adult hippocampal neurogenesis (AHN) is a promising strategy ... -
Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation
Sampedro-Piquero, Patricia; Ladrón de Guevara-Miranda, David; Pavón-Morón, Francisco Javier; Serrano, Antonia; Suárez-Pérez, Juan; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (Elsevier, 2019)
Drug addiction is a chronic and relapsing disorder in which repeated drug exposure compromises brain neuroplasticity. Brain areas normally involved in learning and goal- directed behaviors become corrupted, which may lead ... -
Plasma Amino Acid Concentrations in Patients with Alcohol and/or Cocaine Use Disorders and Their Association with Psychiatric Comorbidity and Sex
(IOAP-MPDI, 2022-05-14)(1) Background: Co-occurrence of mental and substance use disorders (SUD) is prevalent, but complicates their clinical courses, and specific biomarkers are required. Amino acids are altered in primary mental disorders; ... -
Plasma Concentrations of Lysophosphatidic Acid and Autotaxin in Abstinent Patients with Alcohol Use Disorder and Comorbid Liver Disease.
Flores-López, María; García-Marchena, Nuria; Pavón-Morón, Francisco Javier; Lara, Estrella; Porras Perales, Óscar; Araos, Pedro; Requena-Ocaña, Nerea; Torres-Galván, Sandra; Mañas-Padilla, María del Carmen; Rubio, Gabriel; Suárez-Pérez, Juan; Santín-Núñez, Luis Javier; Rodriguez-de-Fonseca, Fernando; Castilla-Ortega, María Estela; García-Fernández, María Inmaculada; Serrano, Antonia[et al.] (2021-09-13)
Lysophosphatidic acid (LPA) is an endogenous lysophospholipid and a bioactive lipid that is synthesized by the enzyme autotaxin (ATX). The ATX-LPA axis has been associated with cognitive dysfunction and inflammatory diseases, ... -
Sex Differences in Plasma Lysophosphatidic Acid Species in Patients with Alcohol and Cocaine Use Disorders
Flores-López, María; García-Marchena, Nuria; Araos Gómez, Pedro Fernando; Requena-Ocaña, Nerea; Porras-Perales, Oscar; Torres-Galván, Sandra; Suárez-Pérez, Juan; Pizarro Lozano, Nieves; De la Torre, Rafael; Rubio, Gabriel; Ruiz-Ruiz, Juan Jesús; Rodriguez-de-Fonseca, Fernando; Serrano, Antonia; Pavón-Morón, Francisco Javier[et al.] (IOAP-MPDI, 2022-04-30)
Preclinical evidence suggests a main role of lysophosphatidic acid (LPA) signaling in drug addiction. Recently, we reported alterations in the plasma concentrations of LPA species in patients with alcohol use disorder ... -
The impact of cocaine on adult hippocampal neurogenesis: Potential neurobiological mechanisms and contributions to maladaptive cognition in cocaine addiction disorder
(Elsevier, 2017-10-01)After discovering that addictive drugs alter adult neurogenesis, the potential role of adult-born hippocampal neurons in drug addiction has become a promising research field, in which cocaine is the most frequently ...