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- Psicobiología y Metodología de las Ciencias del Comportamiento - (PMCC)
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Listar PMCC - Artículos por autor "Castro-Zavala, Adriana"
Mostrando ítems 1-4 de 4
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A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease
Esteban-Martos, Alvaro; Brokate-Llanos, Ana María; Real-Navarrete, Luis Miguel; Melgar-Locatelli, Sonia; De Rojas, Itziar; Castro-Zavala, Adriana; Bravo-Romero, María José
; Mañas-Padilla, María del Carmen; García-González, Pablo; Ruiz-Galdón, Maximiliano
; Pacheco-Sánchez, Beatriz; Polvillo, Rocío; Rodriguez-de-Fonseca, Fernando; González, Irene; Castilla-Ortega, María Estela
; Muñoz-Gómez, Manuel
; Rivera, Patricia; Reyes-Engel, Armando
; Ruiz, Agustín; Royo-Sánchez-Palencia, José Luis
[et al.] (MDPI, 2023)
Genome-wide association studies (GWAS) constitute a powerful tool to identify the different biochemical pathways associated with disease. This knowledge can be used to prioritize drugs targeting these routes, paving the ... -
Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Rivera, Patricia; Razola-Díaz, María del Carmen; Monje, Francisco J; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela; Razola-Díaz[et al.] (Royal Society of Chemistry, 2024-08-12)
Cocoa is widely known for its health benefits, but its neurocognitive impact remains underexplored. This preclinical study aimed to investigate the effects of cocoa and cocoa polyphenols on hippocampal neuroplasticity, ... -
Nutrition and adult neurogenesis in the hippocampus: Does what you eat help you remember?
Melgar-Locatelli, Sonia; De Glecia, María Luisa; Mañas-Padilla, María del Carmen; Rodríguez-Pérez, Celia; Castilla-Ortega, Celia; Castro-Zavala, Adriana; Rivera, Patricia[et al.] (2023-02-23)Neurogenesis is a complex process by which neural progenitor cells (NPCs)/neural stem cells (NSCs) proliferate and differentiate into new neurons and other brain cells. In adulthood, the hippocampus is one of the areas ... -
Sex-Specific Variations in Spatial Reference Memory Acquisition: Insights from a Comprehensive Behavioral Test Battery in C57BL/6JRj Mice.
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Gavito, Ana Luisa; Rivera, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela; Castro-Zavala, Adriana[et al.] (2023)
Sex differences in declarative memory are described in humans, revealing a female or a male advantage depending on the task. Specifically, spatial memory (i.e., spatial navigation) is typically most efficient in men. This ...