Listar PMCC - Artículos por título
Mostrando ítems 10-18 de 18
-
Neuroplastic and cognitive impairment in substance use disorders: a therapeutic potential of cognitive stimulation
(Elsevier, 2019)Drug addiction is a chronic and relapsing disorder in which repeated drug exposure compromises brain neuroplasticity. Brain areas normally involved in learning and goal- directed behaviors become corrupted, which may lead ... -
New Evidence for the Psychometric Properties of the Spanish Version of the Gain in Alzheimer Care Instrument
(Cambridge, 2021-05-07)The aim was to analyze the psychometric properties of the Spanish version of the Gain in Alzheimer Care Instrument (GAIN), providing validity evidence based on its internal structure, reliability, item analysis, and ... -
Patients with Schizophrenia Showed Worse Cognitive Performance than Bipolar and Major Depressive Disorder in a Sample with Comorbid Substance Use Disorders
(IOAP-MPDI, 2022-11-09)Comorbidity of substance use disorders (SUD) and severe mental illness (SMI) is highly frequent in patients, the most common diagnoses being schizophrenia (SZ), bipolar disorder (BD) and major depressive disorder (MDD). ... -
Persistent changes in exploration and hyperactivity coexist with cognitive impairment in mice withdrawn from chronic cocaine
(Elsevier, 2021)Repeated cocaine exposure induces lasting neurobehavioral adaptations such as cognitive decline in animal models. However, persistent changes in spontaneous –unconditioned- motor and exploratory responses are scarcely ... -
Plasma Amino Acid Concentrations in Patients with Alcohol and/or Cocaine Use Disorders and Their Association with Psychiatric Comorbidity and Sex
(IOAP-MPDI, 2022-05-14)(1) Background: Co-occurrence of mental and substance use disorders (SUD) is prevalent, but complicates their clinical courses, and specific biomarkers are required. Amino acids are altered in primary mental disorders; ... -
Remote memory of drug experiences coexists with cognitive decline and abnormal adult neurogenesis in an animal model of cocaine-altered cognition
(Wiley, 2021)Cocaine addiction is a chronic disorder in which the person loses control over drug use. The past memories of the stimuli associated with the drug are a relevant clinical problem, since they trigger compulsive drug seeking ... -
Sex Differences in Plasma Lysophosphatidic Acid Species in Patients with Alcohol and Cocaine Use Disorders
(IOAP-MPDI, 2022-04-30)Preclinical evidence suggests a main role of lysophosphatidic acid (LPA) signaling in drug addiction. Recently, we reported alterations in the plasma concentrations of LPA species in patients with alcohol use disorder ... -
Training memory without aversion: Appetitive hole-board spatial learning increases adult hippocampal neurogenesis
(Elsevier, 2018)(AHN). However, the vast majority of findings on the learning-induced regulation of AHN derive from aversively-motivated tasks, mainly the water maze paradigm, in which stress is a confounding factor that affects the AHN ... -
Where to place the rewards? Exploration bias in mice influences performance in the classic hole-board spatial memory test
(Springer, 2019)The classic hole-board paradigm (a square arena with 16 holes arranged equidistantly in a 4x4 pattern) assesses both exploration and spatial memory in rodents. For spatial memory training, food rewards are hidden in a fixed ...