Listar PMCC - Artículos por título
Mostrando ítems 1-20 de 79
-
A Functional Pipeline of Genome-Wide Association Data Leads to Midostaurin as a Repurposed Drug for Alzheimer’s Disease
Esteban-Martos, Alvaro; Brokate-Llanos, Ana María; Real-Navarrete, Luis Miguel
; Melgar-Locatelli, Sonia; De Rojas, Itziar; Castro-Zavala, Adriana; Bravo-Romero, María José; Mañas-Padilla, María del Carmen; García-González, Pablo; Ruiz-Galdón, Maximiliano; Pacheco-Sánchez, Beatriz; Polvillo, Rocío; Rodriguez-de-Fonseca, Fernando; González, Irene; Castilla-Ortega, María Estela; Muñoz-Gómez, Manuel; Rivera, Patricia; Reyes-Engel, Armando; Ruiz, Agustín; Royo-Sánchez-Palencia, José Luis[et al.] (MDPI, 2023)
Genome-wide association studies (GWAS) constitute a powerful tool to identify the different biochemical pathways associated with disease. This knowledge can be used to prioritize drugs targeting these routes, paving the ... -
Adult hippocampal neurogenesis as a target for cocaine addiction: a review of recent developments
Castilla-Ortega, María Estela; Santín-Núñez, Luis Javier (Elsevier, 2020)
Basic research in rodents has shown that adult hippocampal neurogenesis (AHN) plays a key role in neuropsychiatric disorders that compromise hippocampal functioning. The discovery that dependence-inducing drugs regulate ... -
Assessing Satisfaction With Online Courses: Spanish Version of the Learner Satisfaction Survey
Torrado Herrera, Macarena; Blanca-Mena, María José (Frontiers, 2022-04-27)
The aim of this study was to develop a Spanish version of the Learner Satisfaction Survey (LSS-S) and to analyze its psychometric properties. The questionnaire was administered to a sample of 1,194 university students. ... -
Bias, Precision, and Accuracy of Skewness and Kurtosis Estimators for Frequently Used Continuous Distributions.
Bono Cabré, Roser; Arnau Gras, Jaume; Alarcón-Postigo, Rafael; Blanca-Mena, María José (MDPI, 2019-12-20)
Several measures of skewness and kurtosis were proposed by Hogg (1974) in order to reduce the bias of conventional estimators when the distribution is non-normal. Here we conducted a Monte Carlo simulation study to compare ... -
Character strengths as protective factors against engagement in sexting in adolescence
Yépez-Tito, Pula A.; Ferragut-Ortiz-Tallo, Marta; Blanca-Mena, María José (Editum. Servicio de Publicaciones de la Universidad de Murcia., 2021)
El sexting es una nueva forma de interacción sexual en adolescentes que ha sido asociada tanto a problemas psicológicos como comportamientos de riesgo sexual. Aunque varios estudios han examinado la relación entre sexting ... -
Child sexual abuse in mexican women: type of experience, age, perpetrator and disclosure
Rueda-Gallego, Pilar; Ferragut-Ortiz-Tallo, Marta; Cerezo-Guzmán, María Victoria; Ortiz-Tallo-Alarcón, Margarita (MDPI, 2021)
Child sexual abuse (CSA) is a type of maltreatment that occurs in practically all countries and social statuses. Due to the taboo and shame that surrounds it, CSA is a problem universally silenced despite the important ... -
Chronic central modulation of LPA/LPA receptors-signaling pathway in the mouse brain regulates cognition, emotion, and hippocampal neurogenesis.
Rosell-del-Valle, Cristina; Pedraza-Benítez, María del Carmen; Manuel, Iván; Moreno-Rodríguez, Marta; Rodríguez-Puertas, Rafael; Castilla-Ortega, María Estela; Caramés-Tejedor, José María; Gómez-Conde, Ana Isabel; Zambrana-Infantes, Emma; Ortega-Pinazo, Jesús; Serrano-Castro, Pedro Jesús; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Estivill-Torrús, Guillermo[et al.] (Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2021-06-06)
Several studies have demonstrated that lysophosphatidic acid (LPA) acts through its LPA receptors in multiple biological and behavioral processes, including adult hippocampal neurogenesis, hippocampal-dependent memory, and ... -
Circadian rhythmicity in schizophrenia male patients with and without substance use disorder comorbidity
Adan-Puig, Ana; Marquez-Arrico, Julia; Río Martínez, Laura; Navarro-Humanes, José Francisco; Martínez-Nicolás, Antonio (Springer, 2023-03-06)
Circadian rhythmicity is associated to clinical variables that play an important role in both schizophrenia (SZ) and substance use disorders (SUD), although the characteristics of the coexistence of these two diagnoses ... -
Clasificación multiaxial de agresores de pareja en centros penitenciarios
Loinaz, Ismael; Ortiz-Tallo-Alarcón, Margarita; Sánchez-Rodríguez, Luis Miguel; Ferragut-Ortiz-Tallo, Marta (Elsevier, 2011)
En el presente estudio ex post facto se describe la evaluación y clasificación llevada a cabo en un centro penitenciario con 48 agresores de pareja y se comparan los resultados con un estudio desarrollado anteriormente ... -
Cocaine-conditioned place preference is predicted by previous anxiety-like behavior and is related to an increased number of neurons in the basolateral amygdala
(Elsevier, 2016-02-01)The identification of behavioral traits that could predict an individual's susceptibility to engage in cocaine addiction is relevant for understanding and preventing this disorder, but investigations of cocaine addicts ... -
Cognitive reserve mediates the severity of certain neuropsychological deficits related to cocaine use disorder
Vicario, Selene; Pérez-Rivas, Aroa; Ladrón de Guevara-Miranda, David; Santín-Núñez, Luis Javier; Sampedro-Piquero, Patricia (Elsevier, 2020-08)
The concept of cognitive reserve (CR) is being considered in the field of substance use disorder (SUD) by observing that there are individuals whose brain alterations are not related to the cognitive symptomatology they ... -
Development and Psychometric Properties of the Questionnaire for Assessing Educational Podcasts (QAEP).
Alarcón-Postigo, Rafael; Blanca-Mena, María José (Frontiers, 2020-11-23)
The aim of this research was to develop and validate the Questionnaire for Assessing Educational Podcasts (QAEP), an instrument designed to gather students’ views about four dimensions of educational podcasts: access and ... -
Development and psychometric properties of the stressors in Breast Cancer Scale.
Cerezo-Guzmán, María Victoria; Soria-Reyes, Lorena M.; Pajares, Bella; Gómez-Millán Barrachina, Jaime; Blanca-Mena, María José (Frontiers, 2023-03-28)
Background: A diagnosis of breast cancer generates psychological stress, due not only to treatment and its side effects but also to the impact on different areas of the patient’s daily life. Although there are instruments ... -
Diet enriched with high-phenolic cocoa potentiates hippocampal brain-derived neurotrophic factor expression and neurogenesis in healthy adult micewith subtle effects on memory
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Rivera, Patricia; Razola-Díaz, María del Carmen; Monje, Francisco J; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela; Razola-Díaz[et al.] (Royal Society of Chemistry, 2024-08-12)
Cocoa is widely known for its health benefits, but its neurocognitive impact remains underexplored. This preclinical study aimed to investigate the effects of cocoa and cocoa polyphenols on hippocampal neuroplasticity, ... -
Do changes in microglial status underlie neurogenesis impairments and depressive-like behaviours induced by psychological stress? A systematic review in animal models
Nieto-Quero, Andrea; Chaves-Peña, Patricia; Santín-Núñez, Luis Javier; Pérez-Martín, Margarita; Pedraza-Benítez, María del Carmen (ELSEVIER, 2021-11)
Stress may have a negative effect on mental health and is the primary environmental risk factor in the aetiology of depression. Nevertheless, the neurobiological mechanisms underlying this mood disorder remain ... -
Donepezil alone and combined with intensive language-action therapy on depression and apathy in chronic post-stroke aphasia: A feasibility study
Berthier-Torres, Marcelo Luis; Edelkraut, Lisa; López-González, Francisco Javier; López-Barroso, Diana; Mohr, Bettina; Pulvermüller, Friedemann; Starkstein, Sergio E.; Jorge, Ricardo E.; Torres-Prioris, María José; Dávila-Arias, María Guadalupe[et al.] (Elsevier, 2022-12-07)
This study explored the feasibility and effectiveness of a short-term (10-week) intervention trial using Donepezil administered alone and combined with intensive language action therapy (ILAT) for the treatment of apathy ... -
Early intervention services during the COVID-19 pandemic in Spain: toward a model of family-centered practices.
Vilaseca Momplet, Rosa; Ferrer, Fina; Rivero, Magda; Bersabé-Morán, Rosa María (Frontiers, 2021-11-11)
Early intervention services (EIS) worked hard to continue serving children and their families during the COVID-19 lockdown, using online applications. This study aimed to determine families’ and professionals’ perceptions ... -
Effect of variance ratio on ANOVA robustness: Might 1.5 be the limit?
Blanca-Mena, María José; Alarcón-Postigo, Rafael; Arnau, Jaume; Bono Cabré, Roser; Bendayan, Rebecca (Springer, 2017-06-22)
Inconsistencies in the research findings on F-test robustness to variance heterogeneity could be related to the lack of a standard criterion to assess robustness or to the dif ferent measures used to quantify heterogeneity. ... -
Effectiveness of child sexual abuse prevention programs on knowledge acquisition: A meta-analytical study
Cerezo-Guzmán, María Victoria; Ferragut-Ortiz-Tallo, Marta; Ortiz-Tallo-Alarcón, Margarita; Rodríguez-Fernandez, Raquel (Elsevier, 2023-10-05)
Background: Child sexual abuse (CSA) is a type of maltreatment considered a global health problem. CSA is a traumatic experience with important consequences for the victim’s health. It is essential to report the effectiveness ...