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dc.contributor.authorMolina-Mesa, Soledad
dc.contributor.authorMartínez-Cendán, Juan Pedro
dc.contributor.authorMoyano-Rubiales, Daniel
dc.contributor.authorCubillas-Rodríguez, Inmaculada
dc.contributor.authorMolina-García, Jorge Antonio 
dc.contributor.authorGonzález-Mesa, Ernesto Santiago 
dc.date.accessioned2023-02-02T12:16:22Z
dc.date.available2023-02-02T12:16:22Z
dc.date.issued2022-11-09
dc.identifier.citationMolina-Mesa, S.; Martínez-Cendán, J.P.; Moyano-Rubiales, D.; Cubillas-Rodríguez, I.; Molina-García, J.; González-Mesa, E. Detection of Relevant Heavy Metal Concentrations in Human Placental Tissue: Relationship between the Concentrations of Hg, As, Pb and Cd and the Diet of the Pregnant Woman. Int. J. Environ. Res. Public Health 2022, 19, 14731. https://doi.org/10.3390/ijerph192214731es_ES
dc.identifier.urihttps://hdl.handle.net/10630/25886
dc.description.abstractHeavy metals can cross the placental barrier and reach the fetal compartment, threatening fetal development. Pregnant women can acquire these through food, drinking water, toxic habits or simply by breathing polluted air. The placenta has been described as a biomarker of maternal and fetal exposure to different toxic elements. Objectives: The main objective of this study was to test the possible existence of heavy metal deposits (Pb, As, Cd and Hg) in the placentas of women who gave birth at term in our setting, analyzing the influence of daily life and dietary habits. Methods: We studied 103 placentas, obtained by consecutive sampling, of women that delivered in the Regional Maternity Hospital of Malaga between March and June, 2021. As, Cd and Pb concentrations were analyzed using mass spectrometry techniques. Hg concentration was studied according to US EPA method 7473. Women also answered a questionnaire with epidemiological variables. Results: Detectable concentrations were found in 14.56% [As], 44.6% [Cd], 81.5% [Pb] and 100% [Hg]. [Pb] and [As] correlated significantly (Spearman’s Rho of 0.91 and <0.001), as did [Hg] and [Cd] (Spearman’s Rho 0.256, p < 0.004). The [Pb] and [AS] concentrations were significantly higher in cases of tap water consumption. [Hg] concentrations predicted the birth weight of female newbornses_ES
dc.description.sponsorshipThis research received no external funding. This article is part of Soledad Molina-Mesa’s doctoral thesis. Partial funding for open access charge: Universidad de Málagaes_ES
dc.language.isoenges_ES
dc.publisherIOAP-MPDIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPlacentaes_ES
dc.subject.otherHeavy metalses_ES
dc.subject.otherPlacentaes_ES
dc.subject.otherCadmiumes_ES
dc.subject.otherArsenices_ES
dc.subject.otherLeades_ES
dc.subject.otherMercuryes_ES
dc.subject.otherContaminantses_ES
dc.subject.otherPregnancyes_ES
dc.subject.otherToxicityes_ES
dc.subject.otherDietary habitses_ES
dc.titleDetection of Relevant Heavy Metal Concentrations in Human Placental Tissue: Relationship between the Concentrations of Hg, As, Pb and Cd and the Diet of the Pregnant Womanes_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.centroFacultad de Medicinaes_ES
dc.identifier.doihttps://doi.org/10.3390/ijerph192214731
dc.rights.ccAtribución 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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