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dc.contributor.authorCerezo Ortega, Isabel M.
dc.contributor.authorPérez-Gómez, Olivia
dc.contributor.authorBautista-Moreno, Rocío 
dc.contributor.authorSeoane, Pedro
dc.contributor.authorEsteban-Abad, María Ángeles
dc.date.accessioned2023-02-20T12:18:22Z
dc.date.available2023-02-20T12:18:22Z
dc.date.issued2023-01-04
dc.identifier.citationCerezo IM, Pérez-Gómez O, Bautista R, Seoane P, Esteban MÁ, Balebona MC, Moriñigo MA, Tapia-Paniagua ST. SpPdp11 Administration in Diet Modified the Transcriptomic Response and Its Microbiota Associated in Mechanically Induced Wound Sparus aurata Skin. Animals. 2023; 13(2):193. https://doi.org/10.3390/ani13020193es_ES
dc.identifier.urihttps://hdl.handle.net/10630/25998
dc.description.abstractSkin lesions are a frequent fact associated with intensive conditions affecting farmed fish. Knowing that the use of probiotics can improve fish skin health, SpPdp11 dietary administration has demonstrated beneficial effects for farmed fish, so its potential on the skin needs to be studied more deeply. The wounded specimens that received the diet with SpPdp11 showed a decrease in the abundance of Enterobacteriaceae, Photobacterium and Achromobacter related to bacterial biofilm formation, as well as the overexpression of genes involved in signaling mechanisms (itpr3), cell migration and differentiation (panxa, ttbk1a, smpd3, vamp5); and repression of genes related to cell proliferation (vstm4a, areg), consistent with a more efficient skin healing processes than that observed in the wounded control group. In addition, among the groups of damaged skin with different diets, Achromobacter, f_Ruminococcaceae, p_Bacteroidetes, Fluviicola and Flavobacterium genera with significant differences showed positive correlations with genes related to cell migration and negative correlations with inflammation and cell proliferation and may be the target of future studies.es_ES
dc.description.sponsorshipEste estudio fue apoyado por subvenciones del Ministerio de Economía y Competitividad (MINECO) (AGL-2017-83370-C1-R y AGL-2017-83370-C3-R). Partial funding for open access charge: Universidad de Málagaes_ES
dc.language.isoenges_ES
dc.publisherIOAP-MDPIes_ES
dc.rightsinfo:eu-repo/semantics/openAccesses_ES
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectPieles_ES
dc.subject.otherAquaculturees_ES
dc.subject.otherFishes_ES
dc.subject.otherGilthead seabreames_ES
dc.subject.otherMicrobiotaes_ES
dc.subject.otherProbiotices_ES
dc.subject.otherRNA seqes_ES
dc.subject.otherSkines_ES
dc.subject.otherWoundes_ES
dc.titleSppdp11 administration in diet modified the transcriptomic response and its microbiota associated in mechanically induced wound Sparus aurata skin.es_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.centroFacultad de Cienciases_ES
dc.identifier.doihttps://doi.org/10.3390/ani13020193
dc.rights.ccAtribución 4.0 Internacional*
dc.type.hasVersioninfo:eu-repo/semantics/publishedVersiones_ES


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