Despite the existence of laws on reserve quotas for people with disabilities (PwD), this group continues to experience high unemployment rates and social exclusion. This research has aimed to empirically analyze the influence of the hiring of PwD on the performance and reputation of the firm. We have carried out a quantitative study of European companies to highlight the value and benefits that these workers can bring, and thus overcome prejudices and stereotypes of employers that consider them problematic or unproductive. Our longitudinal research demonstrates that the hiring of PwD contributes positively to the performance and reputation of the firm, helping companies obtain competitive advantages and acting as a brand for the firm. This study gives rise to theoretical, managerial, practical, and political implications.