Dataset for: A persistent increase in gut permeability correlates with emotional dysregulation following maternal separation in male and female mice.

Abstract

Early life stress (ELS) can significantly influence vulnerability to the development of psychiatric disorders in adulthood. One of the most widely used preclinical models for investigating ELS is maternal separation with early weaning (MSEW), which mimics early-life neglect. The objective of this study was to evaluate the impact of ELS induced by MSEW on the emotional behaviour of male and female mice, as well as its relationship with intestinal permeability and neuroinflammatory markers in the hippocampus.