- RIUMA Principal
- Investigación
- Biología Celular, Genética y Fisiología - (BCGF)
- BCGF - Contribuciones a congresos científicos
- Listar BCGF - Contribuciones a congresos científicos por autor
Listar BCGF - Contribuciones a congresos científicos por autor "Dávila-Cansino, José Carlos"
Mostrando ítems 21-24 de 24
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Systemic administration of epothylone-d recues memory and ameliorates Alzheimer’s disease-like pathology in APP/PS1 mice.
Fernández-Valenzuela, Juan José; Sánchez-Varo, Raquel María; De Castro Carratalá, Vanessa; Moyano, Francisco José; Vizuete, María Luisa; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2017-04-17)Aims Cognitive and memory decline in Alzheimer's disease (AD) patients is highly related to synaptic dysfunction and neuronal loss. Tau hyperphosphorylation destabilizes microtubules leading to axonal transport failure, ... -
Tau pathology and astroglial reactivity: a comparative study of two mouse models of tauopathy
Fernández-Valenzuela, Juan José; López Oliva, Elba; Sánchez-Varo, Raquel María; Sánchez-Mejías, Elisabeth; Romero, Carmen; Mejías-Ortega, Marina; Vizuete, María Luisa; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2022)Objectives: Astrocytes are becoming crucial players in the context of neurodegenerative proteinopathies, such as Alzheimer’s disease (AD). Astroglial response has been mainly analyzed in amyloidogenic scenarios, but less ... -
Ultrastructural evidence of mitochondrial pathology in hippocampal reactive astrocytes of β-amyloidosis Alzheimer’s transgenic mice
López Oliva, Elba; Trujillo-Estrada, Laura Isabel; Sánchez-Mejías, Elisabeth; Mejías-Ortega, Marina; Fernández-Valenzuela, Juan José; Gómez-Arboledas, Ángela; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (Cold Spring Harbor Laboratory, 2022)Astrocytes, the most abundant non-neuronal cell type in the CNS, play essential roles in brain homeostasis and neuroprotection, including metabolic support, synaptic plasticity, cerebral blood flow and immunity. Many of ... -
Understanding microglial responses in the frontal cortex of alzheimer´s disease patients
Mejías-Ortega, Marina; Sánchez-Mejías, Elisabeth; Navarro, Victoria; Núñez-Díaz, Cristina; Sánchez-Varo, Raquel María; Jiménez, Sebastián; Dávila-Cansino, José Carlos; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia[et al.] (2021-03-09)Microglial cells, the immune cells of the brain, and the neuroinflammatory process associated, have been postulated as a critical factor in AD pathogenesis, since the identification of genetic risk factors related ...