ListarBCGF - Contribuciones a congresos científicos por tema "Alzheimer, enfermedad de"
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Amyloid-b seeding and propagation processes in a hAb-KI model of Alzheimer's disease
(2020-12-17)Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Coexistance of different myeloid populations in the frontal cortex of alzheimer's disease patients
(2020-12-16)Parenchymal microglia, the brain-resident immune cells capable of responding to damage and disease, has been postulated as a critical factor in the Alzheimer´s disease (AD) progression. Apart from microglia, CNS macrophages, ... -
Microtubule stabilization protects cognitive function and slows down the course of Alzheimer's like pathology in an amyloidogenic mouse model
(2020-12-17)Cognitive decline in Alzheimer's disease (AD) is highly related to synaptic dysfunction and neuronal loss. In AD, the hyperphosphorylation of tau compromises axonal transport and leads to the generation of dystrophic ...