• Amyloid propagation in a sporadic model of Alzheimer disease 

      Andreo-Lopez, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Huynh, Kelly; Nguyen, Marie; [et al.] (2021-11-04)
      Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ...
    • Amyloid-β seeding and propagation processes in a hAβ-KI model of Alzheimer's disease 

      Trujillo-Estrada, Laura; Minh Thu Nguyen, Marie; Baglietto-Vargas, David; LaFerla, Frank; Gutierrez-Perez, Antonia; [et al.] (Cold Spring Harbor Laboratory, 2020-12-02)
      Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ...
    • Human amyloid seeds aggregate more efficient than seeds from old 3xtg-ad mice 

      Andreo-Lopez, Juana; Cantero-Molina, Francisco; Bettinetti-Luque, Miriam; Huynh, Kelly; Thu Nguyen, Marie Minh; [et al.] (2022)
      Aims: Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ...
    • Impact of white adipose tissue in AD pathology 

      Bettinetti-Luque, Miriam; Trujillo-Estrada, Laura; Andreo-Lopez, Juana; Cantero-Molina, Francisco; Rodriguez-Ortiz, Carlos J; [et al.] (2022)
      Aims: Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences has suggested that metabolic alterations are an important ...
    • Impact of white adipose tissue in AD pathology 

      Bettinetti-Luque, Miriam; Andreo-Lopez, Juana; Cantero-Molina, Francisco; Trujillo-Estrada, Laura; Rodriguez-Ortiz, Carlos J; [et al.] (2021-11-04)
      Introduction: Alzheimer’s disease (AD) is a complex disorder and multiple cellular and molecular mechanisms are involved in AD onset and progression. Recent evidences has suggested that metabolic alterations are an important ...