ListarBCGF - Contribuciones a congresos científicos por tema "Glucoproteínas - Congresos"
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Amyloid-β seeding and propagation processes in a hAβ-KI model of Alzheimer's disease
Trujillo-Estrada, Laura Isabel
; Minh Thu Nguyen, Marie; Baglietto-Vargas, David; LaFerla, Frank; Gutierrez-Perez, Antonia; Moreno-Gonzalez, Ines; Soto, Claudio; Shahnawaz, Mohammad; Da Cunha, Celia; Forner, Stefania; Nunez-Diaz, Cristina; Pham Tran, Janine; Cheung, Alwin; Do Huynh, Kelly; Martinie, Alessandra C.[et al.] (Cold Spring Harbor Laboratory, 2020-12-02)
Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Microtubule stabilization reduces amyloid pathology and improves synaptic/memory deficits in APP/PS1 mice
Sanchez-Varo, Raquel; Fernandez Valenzuela, Juan José; Muñoz-Castro, Clara; De Castro, Vanessa; Sanchez-Mejias, Elisabet; Navarro, V; Jimenez, Sebastian; Nuñez-Diaz, Cristina; Gomez-Arboledas, Angela; Moreno-Gonzalez, Ines; Moyano, F; Vizuete, Marisa; Davila, Jose Carlos; Vitorica, Javier; Gutierrez-Perez, Antonia[et al.] (Alzheimer disease & Parkinson disease Conference 2021, 2021)
Aims: Cognitive decline in Alzheimer's disease (AD) is highly related to synaptic/neuronal loss. Tau hyperphosphorylation destabilizes microtubules leading to axonal transport failure and generation of dystrophic neurites, ...