ListarBCGF - Contribuciones a congresos científicos por tema "Microglia"
Mostrando ítems 1-20 de 22
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Anxiety and mild microglial activation in the amygdala two weeks after NA-induced neuroinflammation
(Wiley Periodicals, LLC, 2021-07)A single injection of neuraminidase (NA) within the cerebral ventricles (ICV) triggers an acute neuroinflammation. Neurological complications or behavioral alterations have been associated to neuroinflammation. While some ... -
Chronic ethanol induces morpohological changes on hippocampal microglia, which are reverted by pharmacological blockade of faah with urb597
(2018-11-29)Here, we evaluated the pharmacological effects of fatty-acid amide-hydrolase (FAAH) inhibitor URB597 (0.3 mg/kg), oleoylethanolamide (OEA, 10 mg/kg), arachidonoylethanolamide (AEA, 10 mg/kg), the CB1 receptor agonist ACEA ... -
Coexistance of different damage-associated myeloid populations in the hippocampus of Alzheimer's patients
(Wiley, 2021)Parenchymal microglia are the brain-resident immune cells capable of responding to damage. Though the role of microglial cells in the development/progression of AD is still unknown, a dysfunctional response has recently ... -
Coexistance of different myeloid populations in the frontal cortex of alzheimer's disease patients
(2020-12-16)Parenchymal microglia, the brain-resident immune cells capable of responding to damage and disease, has been postulated as a critical factor in the Alzheimer´s disease (AD) progression. Apart from microglia, CNS macrophages, ... -
Correlation between IL1β expression level and morphological parameters proves the usefulness of morphology measures to predict the degree of activation of microglial cells
(2017-10-04)It is well known that microglial cells undergo an important change in morphology upon activation, so that form and function are intimately related. Upon activation, microglia cell body enlarges, its ramifications shortens ... -
Decoding damage-associated microglia in post mortem hippocampus of Alzheimer’s disease patients
(2019-07-18)The relationship between Alzheimer’s disease (AD) and neuroinflammation has become stronger since the identification of several genetic risk factors related to microglial function. Though the role of microglial cells in ... -
Diversity of plaque-associated myeloid cells subtypes in human alzheimer’s disease brain
(2022)Aims: Parenchymal microglia, as well other myeloid cells, have been postulated as a critical factor in Alzheimer´s disease (AD) pathogenesis since the identification of genetic risk factors related to their functions. ... -
Effects of chronic stress on hippocampal microglia and neurogenesis of mice under social defeat stress.
(2022-07)Introduction: Chronic stress is the main environmental factor in the aetiology of depression and it is known that this type of stress may cause alterations in brain regions such as the hippocampus. Nevertheless, changes ... -
Enhanced stress response in rats that suffered acute neuroinflammation induced by neuraminidase three months before
(2022)Microglial cells are protagonists in neuroinflammatory processes and their activation is a notorious feature of such events. In acute inflammation, microglial cells return to their basal surveillant state in few days. ... -
Involvement of different aβ-associated myeloid populations in the human alzheimer’s brain
(2022)Parenchymal microglia, the brain-resident immune cells, have been postulated as a critical factor in Alzheimer´s disease (AD) since the identification of genetic risk factors related to their functions. Though the role of ... -
Microglial and neurogenic alterations in hypothalamus due to acute stress
(2021-07)Microglial cells are an important glial population known to be involved in several biological processes such as stress response. These cells engage an activated state following a stress insult that may lead to nervous ... -
Microglial response differences between amyloidogenic transgenic models and Alzheimer’s disease patients
(2018-07-20)Aims: The continuing failure to develop an effective treatment for Alzheimer’s disease (AD) reveals the complexity for AD pathology. Increasing evidence indicates that neuroinflammation involving particularly microglial ... -
Microglial responses in the human Alzheimer’s disease frontal cortex
(2019-07-17)The continuing failure to develop an effective treatment for Alzheimer’s disease (AD) reveals the complexity for this pathology. Increasing evidence indicates that neuroinflammation involving particularly microglial ... -
Monocyte-derived cells invade amyloid plaques in human alzheimer’s disease hippocampus.
(2023)Microglia, the brain-resident myeloid cells, play a major role in the immune responses of the nervous system and in the pathogenesis of Alzheimer's disease (AD). However, the presence of peripheral myeloid cells in the AD ... -
Neuraminidase-activated microglia compromise the viability of ependymocytes
(2017-10-04)Neuraminidase (NA) is a sialidase present in the envelope/wall of some virus/bacteria responsible for brain infections, such as flu, mumps or meningitis. The intracerebroventricular injection of NA in the rat brain provokes ... -
Neuraminidase-induced neuroinflammation causes anxiety and microgliosis in the amygdala
(2021)An intracerebroventricular (ICV) injection of neuraminidase (NA) within the lateral ventricles originates an acute event of neuroinflammation, which is solved to a great extent after two weeks. Recently, neurological ... -
Neuraminidase-induced neuroinflammation is largely dependent on microglial TLR4 receptor
(2019-10-01)The sialidase neuraminidase (NA) cleaves terminal sialic acid from glycoproteins and glycolipids. Among its various locations, it is present in the envelope/membrane of some bacteria/viruses (e.g. influenza virus), where ... -
Partial inhibition of CSF1R signaling reverses long-term microglial priming.
(2023)Microglial cells are main actors in acute neuroinflammation, during which they activate to later return to a basal resting state. Sometimes they retain immune memory of previous neuroinflammatory events, turning into ... -
Peripheral myeloid cells infiltrate the hippocampus of Alzheimer's disease patients.
(2023)Microglia, the brain-resident myeloid cells, play a major role in the immune responses of the nervous system and in the pathogenesis of Alzheimer's disease (AD). However, the presence of peripheral myeloid cells in the AD ... -
Primed microglia after acute neuroinflammation may drive an enhanced stress response.
(2023)Microglial cells become activated during acute neuroinflammation and usually they return to their basal surveillant state in a few days. However, sometimes microglia evolve towards a primed state characterized by an ...