ListarBCGF - Contribuciones a congresos científicos por tema "Seed"
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Amyloid propagation in a sporadic model of Alzheimer disease
(2021-11-04)Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
Amyloid-β seeding and propagation processes in a hAβ-KI model of Alzheimer's disease
(Cold Spring Harbor Laboratory, 2020-12-02)Recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like process. Several studies using FAD animal models have demonstrated that ... -
Human amyloid seeds aggregate more efficient than seeds from old 3xtg-ad mice
(2022)Aims: Most age-associated neurodegenerative disorders involve the aggregation of specific proteins within the nervous system, as occurs in Alzheimer’s disease (AD). Recent evidence indicates that Aβ can misfold and aggregate ... -
The effect of different amyloid seeds and animal hosts on amyloid propagation in Alzheimer's Disease
(2022-07-13)Abstract text: Alzheimer's Disease is a neurodegenerative proteinopathy in which recent evidence indicates that Aβ can misfold and aggregate into seeds that structurally corrupt native proteins, mimicking a prion-like ...