ListarBCGF - Contribuciones a congresos científicos por tema "iPSC"
Mostrando ítems 1-6 de 6
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Fast and efficient generation of oligodendrocytes from human induced pluripotent stem cells (hiPSCs)
Garcia-Leon, Juan Antonio
; Cáceres Palomo, Laura; Dávila-Cansino, José Carlos; Vitorica, Javier; Verfaillie, Catherine; Gutierrez-Perez, Antonia[et al.] (Wiley, 2021-07)
Oligodendrocytes (OLs) are highly specialized cells of the central nervous system responsible for myelin production and metabolic support of neurons. Defects in OLs are crucial in several neurodegenerative diseases including ... -
Generation and characterization of human ipscderived neural precursors and astrocytes to model Alzeimer’s disease
(2022)Background: Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. ... -
Human pluripotent stem cell-derived astrocytes from alzheimer´s disease patients for disease modeling
Cáceres Palomo, Laura; López Oliva, Elba; Dávila-Cansino, José Carlos; Vitorica, Javier; Gutierrez-Perez, Antonia; Garcia-Leon, Juan Antonio[et al.] (2022)
Aims: The lack of reliable models of Alzheimer´s disease (AD) has impeded the development of effective therapies. Glial cells have a key role in AD pathology, but this cannot be properly modeled using available animal ... -
Human pluripotent stem cells as a research tool for elucidating the role of glial cells in Alzheimer´s disease
Garcia-Leon, Juan Antonio; Cáceres Palomo, Laura; Dávila-Cansino, José Carlos; Vitorica, Javier; Gutierrez-Perez, Antonia (2020-12-18)
Background: Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. ... -
IPSC differentiation into ependymal progenitors to treat ventricular damage during hydrocephalus
Introduction: During both obstructive congenital hydrocephalus and post-hemorrhagic hydrocephalus additional pathological events are intimately associated with their ethiology: a) a detrimental inflammatory response; b) ... -
Suitability of human-derived cells as a platform for Alzheimer's disease modeling
Cáceres Palomo, Laura; Garcia-Leon, Juan Antonio; Dávila-Cansino, José Carlos; Vitorica, Javier; Gutierrez-Perez, Antonia (2021)
Aims: Alzheimer's disease (AD) is characterized by presenting a complex pathology, not fully resolved yet. This fact, together with the lack of reliable models, has impeded the development of effective therapies. Recently, ...