- RIUMA Principal
- Investigación
- Biología Molecular y Bioquímica - (BMB)
- BMB - Contribuciones a congresos científicos
- Listar BMB - Contribuciones a congresos científicos por autor
Listar BMB - Contribuciones a congresos científicos por autor "Rodríguez-Quesada, Ana María"
Mostrando ítems 1-20 de 30
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AD0157, a pyrrolidinedione fungal metabolite, inhibits angiogenesis by targeting the Akt signaling pathway
García-Caballero, Melissa; Cañedo, Librada; Fernández-Medarde, Antonio; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2014-09-16)In the course of a screening program for the inhibitors of angiogenesis from marine sources, AD0157, a pyrrolidinedione fungal metabolite, was selected for its angiosupressive properties. AD0157 inhibited the growth of ... -
El análogo de las estrigolactonas GR-24 inhibe la angiogénesis in vitro e in vivo
Carrillo Fernández, Paloma; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2016-10-03)Muchas fitohormonas han mostrado un gran potencial en la prevención y terapia contra el cáncer. Las estrigolactonas son hormonas vegetales derivadas de los caroteinoides que están implicadas en la inhibición de la ramificación ... -
Anti-inflammatory potential of aeroplysinin-1, a bioactive compound isolated from the sponge Aplysina aerophoba
Bravo-Ruiz, Inés; Bernal, Manuel; Manrique-Poyato, Maria Inmaculada; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel; Castilla, Laura; Martínez-Póveda, Beatriz Amparo[et al.] (43 Congreso Anual SEBBM, 2021)Aeroplysinin-1 (Apl-1) is a brominated compound isolated from the marine sponge Aplysina aerophoba that has been shown to possess bioactive effects with a broad spectrum of action in in vitro and in vivo assays. Included ... -
Antiangiogenic potential of an anthraquinone metabolite isolated from a marine fungus.
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; García-Caballero, Melissa; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2023)The potential of marine organisms to yield bioactive molecules is vast and largely unexplored. Significantly, certain bioactive compounds derived from the marine environment have already received approval as anticancer ... -
Antioxidant potential of an anthraquinone metabolite isolated from a marine fungus.
Vidal-Valenzuela, Isabel; Torres-Vargas, José Antonio; García-Caballero, Melissa; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2023)Marine ecosystem is a fruitful source of many pharmacologically active. In particular, a number of marine anthraquinones and their derivatives, have been studied for their potential as anticancer and antimetastatic agents, ... -
Antitumor activity of Toluquinol
Torres-Vargas, José Antonio; Sounni, Nor Eddine; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María; García-Caballero, Melissa (2022)Colorectal cancer (CRC) is the third most common cause of cancer mortality worldwide, with more than 1.85 million cases and 850.000 deaths annually1. Currently, the primary methods for treating CRC are surgery, radiotherapy ... -
Antitumor and antiangiogenic potential of solomonamide synthesis intermediates
Carrillo Fernández, Paloma; Cheng-Sánchez, Iván; Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Sarabia-García, Francisco Ramón; Rodríguez-Quesada, Ana María[et al.] (2017-11-09)In this work we developed a new synthetic strategy towards the solomonamides. a novel class of cyclopeptides of marine origin. The described synthetic approach utilized an olefin metathesis reaction to form the [15]-membered ... -
El análogo de las estrigolactonas GR-24 induce cambios en el citoesqueleto de células tumorales y endoteliales y modula su balance rédox
Torres-Vargas, José Antonio; Martínez-Póveda, Beatriz Amparo; Carrillo Fernández, Paloma; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2018-12-12)Las estrigolactonas son hormonas vegetales con estructura terpenoide, implicadas en el control de una serie de procesos que incluyen la inhibición de la ramificación de la raíz y el brote. Recientemente, se ha descrito el ... -
Estudios de preferencia metabólica en células del “microambiente angiogénico”
Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2016-10-03)El "redescubrimiento" del efecto Warburg a principios de este siglo XXI y de la elevada glutaminolisis tumoral han contribuido a un renovado interés por el metabolismo en Oncología. Además, estudios recientes han dado ... -
Evaluation of metabolism and biosignaling in the angiogenic microenvironment as potential targets for therapeutic intervention
Medina-Torres, Miguel Ángel; Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Carrillo Fernández, Paloma; Urdiales-Ruiz, José Luis; Serrano, José J.; Montañez, Raúl; Rodríguez-Quesada, Ana María[et al.] (2017-08-29)The "re-discovery" of Warburg effect at the turn of the present millennium has been a key determinant of the current renewed interest on cancer metabolism. In fact, metabolic reprogramming has been identified as one of the ... -
Evaluation of the anti-angiogenic potential of hydroxytyrosol derivatives
Marrero Capitán, Ana Dácil; Martínez-Póveda, Beatriz Amparo; Castilla, Laura; Gallardo, Elena; Espartero, José L.; Carrillo Fernández, Paloma; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel[et al.] (2018-09-19)Angiogenesis, a process which allows the formation of new vessels from pre-existing ones, is an essential phenomenon for tumor survival since it allows cancer cells to obtain nutrients and oxygen. This explains the increasing ... -
Fasentin, a glucose uptake inhibitor, is also able to inhibit angiogenesis
Ocaña Farfán, María del Carmen; Carrillo Fernández, Paloma; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2017-10-31)The role of glucose on endothelial cell (EC) metabolism and angiogenesis has been an emerging issue in the last few years. Some inhibitors of glucose metabolism, such as 2-deoxyglucose, have been shown to have anti-angiogenic ... -
Gastronomía Bioactiva: compuestos bioactivos en alimentos y quimioprevención en enfermedades de alta prevalencia
Martínez-Póveda, Beatriz Amparo; Marrero Capitán, Ana Dácil; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (43 Congreso Anual SEBBM, 2021)La quimioprevención de enfermedades basada en la dieta ha surgido en los últimos años como un enfoque interesante para la prevención, e incluso la ralentización de fases iniciales, en patologías de alta prevalencia como ... -
Homocysteine treatment alters redox capacity of both endothelial and tumor cells
Díaz-Santiago, Elena Dolores; Rodríguez Caso, Luis; Cárdenas García, Casimiro; Serrano, José J.; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel[et al.] (2015-10-22)Homocysteine is a non-proteinogenic amino acid playing key roles in two interconnected metabolic pathways, namely, the activated methyl cycle and the linear trans-sulfuration pathway that allows the conversion of methionine ... -
Identification and characterization of new anti-angiogenic compounds from natural sources
Carrillo Fernández, Paloma; Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2017-07-21)The inhibition of angiogenesis has attracted broad attention in the field of pharmacological research, not only for cancer, but for other angiogenesis dependent diseases including ophthalmic, cutaneous and inflammatory ... -
Interplay between glucose and palmitate uptake in breast carcinoma in vitro
Ocaña Farfán, María del Carmen; Carrillo Fernández, Paloma; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2018-07-17)One of the most studied tumor cells lines in vitro is the breast carcinoma MDA-MB-231 cell line. Several studies have proved its glycolytic profile, namely known as the Warburg effect. Glutamine oxidation is also important ... -
Lactate Oxidation in Endothelial Cells: A Feature of All Endothelial Cells?
Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Rodríguez-Quesada, Ana María; Medina-Torres, Miguel Ángel (2019-04-24)Metabolism of endothelial cells is a topic that has gained an increasing interest in the last years. This is due to their role in the angiogenic process, which is pathologically upregulated in several diseases, such as ... -
Learning contract, co-operative and flipped learning as useful tools for studying metabolism
Martínez-Póveda, Beatriz Amparo; García Ponce, Ángel Luis; Blanco-López, Ángel; Rodríguez-Quesada, Ana María; Suárez-Marín, María Fernanda; Alonso-Carrión, Francisco José; Medina-Torres, Miguel Ángel[et al.] (2018-06-25)Undergraduate students in Biology identify Metabolic Biochemistry as a particularly difficult subject. This is due to the fact that students need to interconnect properly all the contents of its syllabus throughout their ... -
Marine sponge as a source of antiangiogenic compounds. The case of aeroplysinin-1
Rodríguez-Quesada, Ana María; Martínez-Póveda, Beatriz Amparo; Rodríguez-Nieto, S; Medina-Torres, Miguel Ángel (2014-04-02)The vast majority of the natural compounds that have been previously described as inhibitors of angiogenesis have been isolated from plants and terrestrial microorganisms, mainly due to their higher availability and because ... -
Medida de glucosa en refrescos: una útil herramienta para ilustrar el aprendizaje de los fundamentos del análisis enzimático
Martínez-Póveda, Beatriz Amparo; García-Ponce, Ángel Luis; Blanco-López, Ángel; Medina-Torres, Miguel Ángel; Rodríguez-Quesada, Ana María (2016-11-02)Es indudable la relevancia que el análisis enzimático tiene en el ámbito de la Bioquímica, la Química Clínica y la Química de la Alimentación, entre otras. En la asignatura “Bioquímica Aplicada” de cuarto curso ...