- RIUMA Principal
- Investigación
- Biología Molecular y Bioquímica - (BMB)
- BMB - Contribuciones a congresos científicos
- Listar BMB - Contribuciones a congresos científicos por autor
Listar BMB - Contribuciones a congresos científicos por autor "Urdiales-Ruiz, José Luis"
Mostrando ítems 1-6 de 6
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A role for antizyme inhibitor 2 in the biosynthesis and content of histamine and serotonin in mouse mast cells
Acosta-Andrade, Carlos; Lambertos, Ana; Urdiales-Ruiz, José Luis; Sánchez-Jiménez, Francisca María; Peñafiel, Rafael; Fajardo-Paredes, Ignacio José[et al.] (2015-09-14)Polyamines (putrescine, spermidine and spermine; PAs) are required for the survival of the majority of living cells. Antizymes and antizyme inhibitors are key regulatory proteins of PA levels by affecting ornithine ... -
A role for antizyme inhibitor 2 in the biosynthesis and content of serotonin and histamine in mouse mast cells
Acosta-Andrade, Carlos; Lambertos, Ana; Urdiales-Ruiz, José Luis; Sánchez-Jiménez, Francisca María; Peñafiel, Rafael; Fajardo-Paredes, Ignacio José[et al.] (2015-09-04)Polyamines (putrescine, spermidine and spermine; PAs) are essential for the majority of living cells. Antizymes and antizyme inhibitors are key regulatory proteins of PA levels by affecting ornithine decarboxylase and PA ... -
An ecological model of invasion and metastasis
Serrano, José J.; Urdiales-Ruiz, José Luis; Medina-Torres, Miguel Ángel; Montañez, Raúl (2017-08-29)It has been argued that malignat tumours represent complex dynamic and self-organizing ecosystems. Furthermore, there is increasing evidence that collective cell migration occurs during invasion and metastasis. Here, we ... -
Evaluation of metabolism and biosignaling in the angiogenic microenvironment as potential targets for therapeutic intervention
Medina-Torres, Miguel Ángel; Ocaña Farfán, María del Carmen; Martínez-Póveda, Beatriz Amparo; Carrillo Fernández, Paloma; Urdiales-Ruiz, José Luis; Serrano, José J.; Montañez, Raúl; Rodríguez-Quesada, Ana María[et al.] (2017-08-29)The "re-discovery" of Warburg effect at the turn of the present millennium has been a key determinant of the current renewed interest on cancer metabolism. In fact, metabolic reprogramming has been identified as one of the ... -
Sensitivity of polyamine metabolism to glucose deprivation is increased in neuroblastoma cells with N-myc amplification
Ruiz-Pérez, M. Victoria; Urdiales-Ruiz, José Luis; Sánchez-Jiménez, Francisca María; Medina-Torres, Miguel Ángel (2014-07-10)Ornithine-derived polyamines are essential for cell proliferation, and their levels are elevated in many human tumors. Neuroblastoma, the most frequent extra-cranial solid tumor in children, harbors amplification of n-myc ... -
Structural and functional interaction between polyamine related molecules and biological membranes
Acosta-Andrade, Carlos; Artetxe, I; Lete, MG; Ruiz-Mirazo, Kepa; Goñi, Félix; Urdiales-Ruiz, José Luis; Fajardo-Paredes, Ignacio José; Sánchez-Jiménez, Francisca María[et al.] (2016-09-22)Changes induced by PA on nucleic acid (NA) conformation and synthesis is proven to be a major reason for PA essentiality (1-3). However, PA interactions with other polyanions, for instance polyanionic membrane lipid bilayers ...