• Metabolic channelingof phe for lignin biosynthesis in maritime pine 

      El-Azaz, Jorge; De la Torre, Fernando; Pascual, María Belén; Ávila, Concepción; Canovas-Ramos, Francisco Miguel (2016-09-02)
      METABOLIC CHANNELING OF PHE FOR LIGNIN BIOSYNTHESIS IN MARITIME PINE Jorge El-Azaz, Fernando de la Torre, Belén Pascual, Concepción Ávila and Francisco M. Cánovas Departamento de Biología Molecular y Bioquímica, ...
    • Metabolic preference studies in cells of the tumor microenvironment 

      Ocaña, Mª Carmen; Martínez-Poveda, Beatriz; Quesada, Ana R.; Medina, Miguel Ángel (2016-10-03)
      In the last years, the rediscovery of the Warburg effect and high tumoral glutaminolysis has lead to a renewed interest in cancer metabolism. Moreover, recent studies have put some importance in endothelial cells metabolism. ...
    • Metabolite profiling of postharvest senescence in different strawberry cultivars 

      Pott, Delphine; de Abreu e Lima, Francisco; Willmitzer, Lothar; Fernie, Alisdair; Nikoloski, Zoran; [et al.] (2019-05-10)
      The cultivated strawberry (Fragaria x ananassa) is the berry most consumed worldwide, being well appreciated for its flavour and nutritional characteristics. However, strawberries possess a very short postharvest shelf-life ...
    • Metabolomic characterization of strawberry cultivars during postharvest 

      Pott, Delphine; Osorio-Algar, Sonia; Vallarino, Jose G (2018-07-12)
      The cultivated strawberry (Fragaria x ananassa) is the berry most consumed worldwide and is well-known for its delicate flavour and nutritional characteristics. However, strawberries possess a very short postharvest ...
    • Metabolomics profiling of strawberry (Fragaria x ananassa) F1 population to characterize flavour and nutritional traits 

      Potss, Delphine; Medina, Juan Jesus; Fernie, Alisdair R; Amaya, Iraida; Vallarino, Jose G; [et al.] (2018-02-27)
      The cultivated strawberry (Fragaria x ananassa) is a highly consumed fruit known for its delicate flavour and nutritional characteristics. However, as fruit quality attributes have been lost after years of traditional ...
    • Multidisciplinary teaching of Biotechnology and Omics sciences 

      Cañas, Rafael A.; De la Torre, Fernando; Pascual, Belen M; El-Azaz Ciudad, Jorge; Cantón, Francisco R.; [et al.] (2017-10-27)
      In the last years, there was a great boom in the Omics fields that have developed as multidisciplinary sciences. They use laboratory techniques related to Biology and Chemistry but also Bioinformatics tools. However, the ...
    • Multiomic studies to improve fruit quality of berry fruits 

      Jimenez, Lidia; Pott, Delphine; Duran, Sara; Mott, Daniella; Petit, Aurélie; [et al.] (2019-02-21)
      In this study we are going to use different omic-techniques to analyze fruits of three species of berries such as strawberry, raspberry and black currant. Berry fruit are well appreciated for their delicate flavor and ...
    • NAC-MYB basedtranscriptional networkinvolved in the regulation of phenylalanine biosynthesis in P. pinaster 

      Pascual, María Belén; Cañas, Rafael A.; Craven-Bartle, Blanca; Canovas-Ramos, Francisco Miguel; Ávila, Concepción (2016-09-02)
      P2-2 NAC-MYB-BASED TRANSCRIPCIONAL NETWORK INVOLVED IN THE REGULATION OF PHENYLALANINE BIOSYNTHESIS IN P. PINASTER Mª Belén Pascual, Rafael A. Cañas, Blanca Craven-Bartle, Francisco M. Cánovas and Concepción ...
    • Network perspective of histamine related diseases 

      Moya-García, Aurelio A.; Rodríguez-López, Rocío; Medina, Miguel Ángel; Sánchez-Jiménez, Francisca (2017-08-29)
      Histamine is the most pleiotropic biogenic amine. Produced and stored by a limited set of cells—histaminergic neurons, enterochromaffin-like cells, and mast cells—it broadcasts intercellular communication signals to a wide ...
    • New findings on the cellular effects of newly synthetized histamine in mammalian cells 

      Sánchez-Jiménez, Francisca Maria (2014)
      Histamine (Hia) is the most multifunctional biogenic amine. It is synthetized by histidine decarboxylase (HDC) in a reduced set of mammalian cell types. Mast cells and histaminergic neurons store Hia in specialized organelles ...
    • Nitrogen metabolism and gene expression landscape in maritime pine 

      Cañas, Rafael A.; Ávila, Concepción; Canovas-Ramos, Francisco Miguel (2017-10-30)
      Maritime pine (Pinus pinaster Aiton) is one the most important conifer species in the southwestern Mediterranean region because of its economic and environmental potential. For this reason, a work program in functional ...
    • Nitrogen metabolism in forest trees 

      Canovas-Ramos, Francisco Miguel; Ávila, Concepción; Torre, F de la; Cañas, Rafael A.; Pascual, M.B. (2013-12-17)
      NITROGEN METABOLISM IN FOREST TREES Francisco Cánovas, Concepción Ávila, Fernando N de la Torre, Rafael Cañas, Belén Pascual. Universidad de Málaga Email:canovas@uma.es Forests are essential components ...
    • Nuevas aproximaciones a la asimilación del amonio en la conífera Pinus pinaster 

      Cañas, Rafael Antonio; Ortigosa, Francisco; Valderrama-Martín, José Miguel; Ávila, Concepción; Canovas-Ramos, Francisco Miguel (2018-05-31)
      Las coníferas son plantas bien adaptadas a crecer en suelos con considerables cantidades de amonio. Por este motivo son un buen modelo de estudio de la asimilación de amonio en plantas. El pino marítimo (Pinus pinaster ...
    • Phenylalanine biosynthesis: the role and evolution of arogenate dehydratase gene family in c 

      El-Azaz, Jorge; Canovas-Ramos, Francisco Miguel; De la Torre, Fernando; Ávila, Concepción (2014-06-19)
      In plants, arogenate dehydratase activity (ADT, EC 4.2.1.91) is responsible for the last step in the main pathway for phenylalanine biosynthesis, known as the arogenate pathway, which consist in two steps: the conversion ...
    • Plasma membrane lipid remodeling during cold acclimation is mediated by the ER-PM contact sites-localized synaptotagmins 1 and 3 

      Pérez-Sancho, Jessica; Rosado, Abel; Schapire, Arnaldo; Ruiz-Lopez, Noemi; Osorio, Sonia; [et al.] (2016-10-28)
      Cold acclimation is the capacity of certain plants to increase their freezing tolerance in response to a period of low non-freezing temperatures. Cold acclimation involves a series of biochemical and physiological adaptations, ...
    • Polyamines and other biogenic amines at the molecular basis of low prevalence diseases 

      Sánchez-Jiménez, Francisca (2014-09-26)
      Biogenic amines are amino acid-derived compounds involved in the most important physiological functions: cell proliferation and differentiation, immunity, neurotransmission and neuroendocrine system, fertility. Diseases ...
    • PpNAC1, a main regulator of phenylalanine biosynthesis in p. Pinaster 

      Pascual, Belen M; Llebrés, Maria Teresa; Cañas, Rafael A.; Canovas-Ramos, Francisco Miguel; Avila, C (2017-07-14)
      The metabolism of phenylalanine plays a central role in the channeling of carbon from photosynthesis to the biosynthesis of phenylpropanoids duringwood formation. This crucial pathway is finely regulated primarily at ...
    • PpNAC1, un regulador principal de la biosíntesis y utilización de fenilalanina en pino 

      Pascual, María Belen; Llebrés, Maria Teresa; Craven-Bartle, Blanca; Cañas, Rafael A.; Canovas-Ramos, Francisco Miguel; [et al.] (2018-05-21)
      La regulación transcripcional del metabolismo de la fenilalanina es particularmente importante en las coníferas, especies de vida larga que usan grandes cantidades de carbono en la formación de madera. El factor de ...
    • A practice project to prevent the cookbook model as modus operandi for biochemistry laboratory learning 

      García-Ponce, Angel Luis; Martínez Poveda, Beatriz; Blanco-López, Ángel; Medina Torres, Miguel Ángel; Rodríguez Quesada, Ana (2018-07-02)
      Laboratory learning is a crucial component of chemistry and biochemistry instruction and should be conceived as a way to develop students’ reasoning, technical or practical skills, introducing them into the scientific ...
    • Protein Functional Families to characterise drug-target interactions. 

      Moya-García, Aurelio (Proceedings IWBBIO 2017, 2017)
      The quest for “magic bullets” has been the driving force in drug discovery during the last two decades. However, the increasing rate of drug failure over this period has occurred concurrently with the assumption that a ...