Listar BMB - Contribuciones a congresos científicos por fecha de publicación
Mostrando ítems 1-20 de 200
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Metabolic changes upon GLS inhibition by CB-839 in glioma cell lines
(2012-07-19)Many tumors use Gln for both energy generation and as a biosynthetic precursor. Glutaminases (GAs) catalyze the first step of glutaminolysis by converting glutamine (Gln) into glutamate and ammonia in the mitochondria. In ... -
Changes in the nuclear proteomic profiling of human glioblastoma cells after glutaminase overexpression
(2013)Human glutaminase (GA) enzymes are the products of two genes, GLS and GLS2. GA isozymes play markedly different roles in tumour biology: GLS isoforms (KGA and GAC) are related to cell growth and proliferation, whereas GLS2 ... -
The molecular control of tomato fruit quality traits: the trade off between visual attributes, shelf life and nutritional value
(2013-07-19)Tomato (Solanum lycopersicum) is an established model to study fleshy fruit development and ripening and is an important crop in terms of its economic and nutritional value. Tomato fruit quality is a function of metabolite ... -
The coffee diterpene kahweol is an antitumoral compound for human estrogen receptor-negative breast cancer cells
(SEBBM, 2013-09-04)Although epidemiological studies indicate that coffee consumption is associated with a low incidence of several kinds of cancer, there are still few studies on the anti-tumoral effects of pure bioactive compounds isolated ... -
Caracterización anual del metabolismo de las acículas de Pinus pinaster (Aiton) mediante procedimientos transcriptómicos y metabolómicos
(2013-11-04)El presente trabajo pretende iniciar una serie de estudios sobre el metabolismo nitrogenado en árboles adultos de la conífera Pinus pinaster (Aiton) en condiciones naturales. Durante un año completo se ha caracterizado ... -
Análisis molecular y funcional de los transportadores de amonio (AMT) en pino marítimo (Pinus pinaster)
(2013-11-07)En los bosques de coníferas la mayor parte del nitrógeno inorgánico disponible se encuentra en forma de amonio como fuente primaria de nitrógeno asimilable [1]. El amonio se incorpora por las raíces a través de proteínas ... -
Biosíntesis de aminoácidos aromáticos: análisis estructural y funcional de la familia arogenato dehidratasa en coníferas
(2013-11-07)En las plantas, la actividad enzimática arogenato dehidratasa (ADT) cataliza el último paso de la principal ruta de biosíntesis de fenilalanina, un proceso de gran importancia funcional y cuantitativa, particularmente ... -
Root and shoot growth of Pinus strobus x P. wallichiana somatic plants is influenced by the nitrogen composition of the germination medium
(2013-11-07)Somatic embryogenesis (SE) in conifers has proven to be an useful biotechnological tool for species conservation and mass propagation, but to make it commercially viable, adaptive research is required to convert laboratory ... -
SYT mutations membrane fusions with whole plant hypersensitivity to abiotic stresses
(2013-11-21)Plants undergo continuous exposure to various abiotic stresses in their natural environment. For this reason they have evolved intricate mechanisms to perceive external signals and trigger the physiological changes necessary ... -
Lipidome remodeling during cold acclimation is controles by plasma membrane associated synaptotagmins
(2013-11-25)The lipidome remodeling during cold acclimation is an important evolutionary milestone to plant adaption to sub-optimal temperature conditions. In Arabidopsis, the phospholipid binding protein Synaptotagmin1 (SYT1) ... -
Synaptotagmin1 regulates membrane fusion events that are essential for abiotic stress tolerance in plants
(2013-11-26)Plants undergo continuous exposure to various abiotic stresses in their natural environment. For this reason they have evolved intricate mechanisms to perceive external signals and trigger the physiological changes necessary ... -
Involvement of a Myb transcription factor in the regulation of phenylalanine pathway in maritime pine
(2013-12-05)Wood is traditionally among the most important commercial products because of the high demand that exits for its derivatives. Trees, including conifers, divert large quantities of carbon into the biosynthesis of phenylpropanoids, ... -
Nitrogen metabolism in forest trees
(2013-12-17)NITROGEN METABOLISM IN FOREST TREES Francisco Cánovas, Concepción Ávila, Fernando N de la Torre, Rafael Cañas, Belén Pascual. Universidad de Málaga Email:canovas@uma.es Forests are essential components ... -
New findings on the cellular effects of newly synthetized histamine in mammalian cells
(2014)Histamine (Hia) is the most multifunctional biogenic amine. It is synthetized by histidine decarboxylase (HDC) in a reduced set of mammalian cell types. Mast cells and histaminergic neurons store Hia in specialized organelles ... -
Marine sponge as a source of antiangiogenic compounds. The case of aeroplysinin-1
(2014-04-02)The vast majority of the natural compounds that have been previously described as inhibitors of angiogenesis have been isolated from plants and terrestrial microorganisms, mainly due to their higher availability and because ... -
Transcript profiling of wood transcriptional regulators, wood chemistry and phenotyping in poplar and eucalyptus genotypes growgin under drought, salinity and limiting nitrogen conditions
(2014-06-11)The possibilities for using lignocellulosic biomass produced from forest crops in order to obtain second generation biofuels is a key issue in the current context of climate change and the promotion of renewable energy ... -
Sugar deficiency causes changes in cuticle permeability and cell wall composition that influence fruit postharvest shelf-life
(2014-06-18)The cuticle is a protective layer synthesized by epidermal cells of the plants and consisting of cutin covered and filled by waxes. In tomato (Solanum lycopersicum) fruit, the thick cuticle embedding epidermal cells has ... -
Phenylalanine biosynthesis: the role and evolution of arogenate dehydratase gene family in c
(2014-06-19)In plants, arogenate dehydratase activity (ADT, EC 4.2.1.91) is responsible for the last step in the main pathway for phenylalanine biosynthesis, known as the arogenate pathway, which consist in two steps: the conversion ... -
A central role for bifunctional aspartate/prephenate aminotransferase in the biosynthesis of amino acids in plant plastids.
(2014-06-27)A central role for bifunctional aspartate/prephenate aminotransferase in the biosynthesis of amino acids in plant plastids. Fernando de la Torre, Jorge El-Azaz, Concepción Ávila, Francisco M. Cánovas Departamento de ... -
Sensitivity of polyamine metabolism to glucose deprivation is increased in neuroblastoma cells with N-myc amplification
(2014-07-10)Ornithine-derived polyamines are essential for cell proliferation, and their levels are elevated in many human tumors. Neuroblastoma, the most frequent extra-cranial solid tumor in children, harbors amplification of n-myc ...