Listar COG - Contribuciones a congresos científicos por título
Mostrando ítems 15-34 de 35
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Increased resistance to drugs and longer life cycle by the administration of exogenous agents to normal human cells
(2022)Exogenous HSP70 provides protection against oxidative stress and that it could be a good therapeutic strategy to treat age-related macular degeneration. On the other hand, externally inoculating a heat shock protein to ... -
Intestinal microbiota and colorectal cancer
(2019-01-16)Colorectal cancer may be influenced by changes in the intestinal microbiota that affect the mucosa and cause an immune response capable of producing inflammatory effects. Although there are still few studies in this regard, ... -
Mechanisms of cross resistance between cisplatin and bleomycin in saccharomyces cerevisiae
(2019-01-16)Tumor cells can simultaneously acquire resistance against a diverse group of drugs. This phenomenon is called pleotropic resistance or multidrug resistance. This mechanism could explain the tumor resistance observed in ... -
Metabolism is altered in the process of drug resistance acquisition
(Aseica, 2022)Cells need energy to survive, therefore, they increase the different pathways available to obtain it. This suggests that the cell, due to the cytotoxicity of bleomycin, increases the routes to obtain energy. For this reason, ... -
Methods to study the intestinal microbiota to address the disease in a more precise and personalized way
(2022)FISH, clone collection, DGGE, PCR and metagenomics techniques contribute to the study of the human microbiota in a precise and effective way, constituting very useful diagnostic tools in precision medicine to address patient ... -
Microbiota and body axes as a new therapeutic approach in precision medicine
(2022)There is a marked relationship between the composition and diversity of the microbiota and various diseases distant from the intestine. This relationship occurs through different body axes between the intestine and the ... -
New markers of bleomycin resistance
(2019-01-16)Resistance to chemotherapy is one of the main problems of this type of therapy. Studies carried out determine the usefulness of predictive biomarkers to improve this treatment. The aim of this work is to carry out a ... -
One hundred of cells generations connect the resistance to drugs and the replicative aging mechanisms
(2019-01-17)There are researchs that reveal a relationship between acquired resistance to antineoplastic drugs and aging. Therefore, the identification of genes involved in senescence could have a potential therapeutic utility for ... -
Presence of radon pollution in buildings and risk of cancer
(2022)Radon gas present in the ground penetrates into homes through different routes, accumulating especially in rooms close to the ground. The dose received from radioactivity due to inhalation of radon inside houses poses a ... -
Proteins involved in carbon metabolism induce bleomycin resistance
(Aseica, 2022)S. cerevisiae acquires bleomycin resistance after a long-term exposure to this drug which causes overexpression of TPIS protein. It could be involved in the resistance process. For this reason, it could be good candidates ... -
Proteomic analysis in wild type and cisplatin resistant yeast strain of saccharomyces cerevisiae
(2019-01-16)Research carried out in oncology has allowed the identification and characterization of molecular markers of resistance to antineoplastic drugs. It supposes a great advance and allows the administration of customized ... -
Real-time PCR optimization to identify Mycobacterium tuberculosis complex strains in clinical samples.
(2014-09-11)During recent years several molecular techniques have become available for Mycobacterium tuberculosis complex (MTC) detection,both for clinical samples and for isolates. One of the techniques more widely used is real time ... -
Relationship between chronological aging and acquired resistance to cisplatin in the yeast saccharomyces cerevisiae
(2019-01-17)The Sir2 gene is associated with an increase in longevity in yeasts, worms, flies and rodents. The human homolog, Sirt1, is also involved in longevity, by inhibiting cellular senescence. Studies carry out in tumor cells ... -
Resistance acquisition after seven cycles of in vitro bleomycin exposure
(2019-01-16)Bleomycin is an antineoplastic drug that causes DNA damage by intra- and inter-strand crosslink and DNA strand breaks. This drug is used to treat several types of cancer. The aim of this work is to study the effect of ... -
Resistance to bleomycin increases the chronological life of cells
(2019-01-17)The identification of genes involved in chronological aging could have a potential utility as molecular markers in the chemotherapy treatment of cancer. The aim of this work is to study the relationship between the ... -
Response of normal human cells to stress causing agents and their relationship with ageing and cellular resistance
(, 2022)By applying low doses of a stressor, normal cells increase the number of HSP leading to increased survival. This phenomenon is considered a cellular adaptive response. The results show that treatment with low doses of a ... -
Role of SODC protein in antineoplastic drug resistance
(Aseica, 2022)Cells need homeostasis to survive, therefore, they use the different pathways available to obtain it. The SODC protein overexpression, which is implicated in this process, suggests that could be implicated in the process ... -
Selection of resistance to cisplatin in saccharomyces cerevisiae as a model for antineoplastic drugs studies
(2019-01-16)The budding yeast (S. cerevisiae) is an excellent eukaryotic model to study the antineoplastic drugs effects, due to the well-characterized metabolic and genetic characteristics and the conserved similarity in molecular ... -
The absence of microbiota dysbiosis is essential to maintain a healthy immune system in cancer patients
(2022)Gut microbiota is required for mucosal immunity. The intestinal mucosa is the main location for microbiome-host interactions. The dynamic interaction between microbiome and environmental factors modulate mucosal and systemic ... -
The presence of toxic pollutants in buildings and construction materials increases the risk of cancer
(Aseica, 2022)To this day, construction materials that contain toxic and carcinogenic compounds are still used. These materials contribute to increase the levels of these compounds inside buildings, thus increasing the risk of cancer. ...