FHEFD - Contribuciones a congresos científicos
Envíos recientes
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Gastrointestinal Stromal Tumor (GIST) and its relationship with germline mutations
(2022)We present the case of a 38-year-old man with a history of abdominal paraganglioma 10 years ago, who consulted for hematemesis and asthenia of 5 days' evolution. An upper gastrointestinal endoscopy was performed where a ... -
Diagnostic value of p53 immunohistochemical expression in high-grade serous ovarian carcinoma (HGSC): casuistry in our center in the last three years.
(2022)High-grade serous carcinoma (HGSC) is the most common ovarian carcinoma (70%). Age over 60 years, a family history of breast/ovarian carcinoma, and infertility are risk factors. Etiology remains unknown. These tumours arise ... -
Effectiveness of an R-based software to detect closed-loop cardiovascular interactions and baroreflex impairment in human subjects from the EUROBAVAR data set
(2022)We recently developed an R-based software that could model closedloop cardiovascular interactions. In this study, we applied this tool on the EUROBAVAR data set to further test its applicability. The aim of this work is ... -
Peer-to-peer medical student education: design, experience and evaluation of the impact in learning of 2nd year medical students from the University of Malaga
(2022)Escape rooms have been trending in the past years among young adults, as teamwork, ingenuity and knowledge merge in a both distended but competitive environment. Inspired by it, a physiology escape room was designed for ... -
Oligodendrocyte metabolism throughout its differentiation: immunocytochemistry study and its impact in remyelination
(2022-09-07)Introduction: Oligodendrocytes (OL) role in demyelinating pathologies such as multiple sclerosis and other neurodegenerative diseases is only recently being subject of extensive research. While the genetic and molecular ... -
Pharmacological activation of dopamine D4 receptor prevents morphine-induced tolerance at the rat dorsal horn level
(2022)Morphine is one of the most effective drugs used for pain management. However, prolonged exposition to morphine produces a wide variety of side effects such as tolerance to analgesia, hyperalgesia and addiction. Downregulation ... -
Cuneiform nucleus stimulation modifies laryngeal activity and subglottic pressure in rats
(2022-09-20)The Cuneiform nucleus (CnF) of the mesencephalon has afferent and efferent connections with different regions of the CNS involved in cardiorespiratory control, i.e. dorsolateral part of the Periaqueductal Gray matter (dlPAG) ... -
Role of Insulin-Growth Factor II on mitochondrial recovery in a cellular model of Parkinson's Disease
(Journal of Physiology and Biochemistry, 2022-09)Insulin-growth factor II (IGF-II) has shown antioxidant and neuroprotective effects in some neurodegenerative disorders. ROS causes damage to cellular macromolecules affecting several cellular processes and resulting in ... -
Impact of Dorsolateral Periaqueductal Grey Matter stimulation in laryngeal activity and subglottic pressure in rats
(2022-09-20)The stimulation of the dorsolateral Periaqueductal Gray matter (dlPAG) produces an increase in sympathetic tone that includes an increase in cardiorespiratory parameters (blood pressure, heart rate and respiratory frequency). ... -
Galanin and Neuropeptide Y Interaction Enhances Proliferation of Granule Precursor Cells and Expression of Neuroprotective Factors in the Rat Hippocampus: Role in depression and memory
(2022-09-22)Neuropeptide Y(NPY) Y1 receptor (Y1R) and galanin (GAL) receptor 2 (GALR2) interact in brain regions responsible for mood control and learning and memory processes, emphasizing the hippocampus. The current study assesses ... -
Protein homeostasis as a therapeutical target for Alzheimer’s disease: analysis in the hippocampus of transgenic mouse models
(2022-09)Alzheimer's disease (AD) constitutes the most prevalent form of dementia. There is no cure so there is an urgent need of novel therapeutic targets and treatments. The main histopathological hallmarks of AD brains are ... -
Gastrointestinal cancer: Relationship between histology and microbiota
(2022-09-09)Objectives: Review of the published literature concerning the relationship between microbiome and gastrointestinal cancer. Methods: Present work is focused on systematic research in the most prominent biomedical databases ... -
New augmentation strategy in depression: Galanin (1-15) enhances the behavioral effects of Fluoxetine in the olfactory bulbectomy rat.
(2022-07-12)Major depression is the largest contributor to global disability by years lived with disability. Selective serotonergic reuptake inhibitors, including fluoxetine (FLX), are the most commonly used antidepressant for the ... -
Galanin (1-15) and escitalopram combination in rats reduces alcohol consumption in the ethanol self-administration test and improves escitalopram effects in the forced swimming test.
(2022-07-12)Recently, we described that Galanin(1-15)[GAL(1-15)] enhanced Escitalopram(ESC) effectiveness in depression symptoms. Moreover GAL(1-15) induces a substantial reduction in alcohol consumption. To investigate the effect of ... -
Insulin-like growth factor II neuroprotective effects against mitochondrial-oxidative and neuronal damage induced by CORT and MPP+ in dopaminergic neurons
(2022-07-12)Aims: Parkinson’s disease (PD) affects 1–3% of the population aged over 65. Stress seems to contribute to PD neuropathology, probably by dysregulation of the hypothalamic–pituitary–adrenal axis. Key factors are oxidative ... -
Intranasal Delivery of Galanin 2 and Neuropeptide Y1 Agonists Enhanced Spatial Memory Performance and antidepressant e!ects through Neuronal Precursor Cells Proliferation in the hippocampus
(2022-07-07)Neuropeptide Y(NPY) Y1 receptor (Y1R) and galanin (GAL) receptor 2 (GALR2) interact in brain regions responsible for learning and memory processes, emphasizing the hippocampus. The current study assesses the sustained ... -
On the balance of D2R-MOR and D4R-MOR in the dorsal and ventral striatum. Putative link to morphine dependence and addiction
(8th Mediterranean Neuroscience Society (MNS), 2022-05-30)The widespread distribution of heteroreceptor complexes with allosteric receptor-receptor interactions in the CNS represents a novel integrative molecular mechanism in the plasma membrane of neurons and glial cells. It was ... -
On the role of GPCR heteroreceptor complexes neuromodulation of the Claustrum
(8th Mediterranean Neuroscience Society (MNS), 2022-05-30)G protein-coupled receptors (GPCRs) modulate the synaptic glutamate and GABA transmission of the claustrum. Our work focused on the transmitter-receptor relationships in the claustral catecholamine system and receptor-receptor ... -
Cuneiform nucleus stimulation modifies laryngeal activity and subglottic pressure in spontaneously breathing anaesthetized rats
(2022-07-12)Background Abduction and adduction of the vocal folds are performed by two populations of motoneurons located in the caudal portion of the nucleus Ambiguus (nA). In the rat, the loose formation of the nA contains motoneurons ... -
Dorsolateral Periaqueductal Grey Matter stimulation modifies laryngeal activity and subglottic pressure in spontaneously breathing anaesthetized rats
(2022-07-12)Abduction and adduction of the larynx allow changes in airflow necessary for the vibration of the vocal folds and emission of voice. It is known that stimulation of the Periaqueductal Gray matter (PAG) and nucleus retroambiguus ...