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- Psicobiología y Metodología de las Ciencias del Comportamiento - (PMCC)
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Listar PMCC - Contribuciones a congresos científicos por autor "Castilla-Ortega, María Estela"
Mostrando ítems 1-20 de 25
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A behavioral test battery only reveals Sex-Specific Differences in Spatial Reference Memory Acquisition in C57BL/6JRj Mice
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Gavito, Ana Luisa; Rivera-González, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela; Castro-Zavala, Adriana[et al.] (2024-01-15)Sex disparities in declarative and spatial memory exist in humans, favoring either gender depending on the task. This trend is observed in rats but less so in mice. In our study with C57BL/6JRj mice, we conducted various ... -
Absence of LPA1 receptor results in altered pattern of limbic activation after tail suspension test
Moreno-Fernández, Román D.; Gómez-Salas, Francisco Javier; Pérez-Martín, Margarita; Rosell-del-Valle, Cristina; Castilla-Ortega, María Estela; García-Fernández, María Inmaculada; Chun, Jerold; Rodriguez-de-Fonseca, Fernando; Estivill-Torrús, Guillermo; Santín-Núñez, Luis Javier; Pedraza-Benítez, María del Carmen[et al.] (2016-07-20)Stress serves as an adaptive mechanism and helps organisms to cope with life-threatening situations. However, individual vulnerability to stress and dysregulation of this system may precipitate stress-related disorders ... -
Behavioral traits predicting cocaine-conditioned place reference in mice: role of anxiety adn the basolateral amygdala
Ladrón de Guevara-Miranda, David; Pavón-Morón, Francisco Javier; Serrano, Antonia; Rivera, Patricia; Estivill-Torrús, Guillermo; Suárez-Pérez, Juan; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2016-07-13)Aims. The individual susceptibility to cocaine addiction, a factor of interest in the understanding and prevention of this disorder, may be predicted by certain behavioral traits. However, these are not usually taken into ... -
Cognitive impairment and persistent changes in exploration and hyperactivity in mice after withdrawn from chronic cocaine
Mañas-Padilla, María del Carmen; Ávila-Gámiz, Fabiola; Gil Rodríguez, Sara; Ladrón de Guevara-Miranda, David; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2021)Lasting neurobehavioral adaptations such as cognitive decline are induced by chronic cocaine exposure in animal models. However, persistent changes in motor and exploratory responses are rarely reported. In this study, ... -
Educación superior y emociones, bases epistemológicas de Maturana
Mañas-Padilla, María del Carmen; Edelkraut, Lisa; Castilla-Ortega, María Estela; Araos Gómez, Pedro Fernando (2021-11-20)Introducción. Las emociones serán entendidas como las disposiciones corporales que especifican el dominio de acción en que ese mueve el organismo. Son el fundamento de muchos aspectos de la vida y la educación es parte de ... -
Effect of a spatial memory training on the persistence of cocaine-contextual memory
Ávila-Gámiz, Fabiola; Mañas-Padilla, María del Carmen; Ladrón de Guevara-Miranda, David; Gil Rodríguez, Sara; Rodriguez-de-Fonseca, Fernando; Castilla-Ortega, María Estela; Santín-Núñez, Luis Javier[et al.] (2019-07-03)Modulation of hippocampal memories related with cocaine addiction such as cocaine-context associations could have important clinical implications. It has been shown that learning-related experiences are potent modulators ... -
Effects of cocoa-derived polyphenols treatment in regulating the adverse impacts of early-life stress in male and female mice.
Castro-Zavala, Adriana; Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela (2023)Depression is one of the mental disorders that significantly affects today's society and calls for new treatments. In recent years, the gut microbiota has emerged as a key modulator of behaviour and mood due to the existence ... -
Effects of palmitoylethanolamide in cocaine-induced behaviours
Santín-Núñez, Luis Javier; Zambrana-Infantes, Emma; Galeano, Pablo; Rosell-del-Valle, Cristina; Ladrón de Guevara-Miranda, David; Castilla-Ortega, María Estela; Rodriguez-de-Fonseca, Fernando; Blanco-Calvo, Eduardo[et al.] (2016-07-13)Aims. Cocaine addiction is a chronically relapsing disorder characterized by the compulsion to seek and take the drug. Previous investigations have demonstrated that several drugs of abuse, as cocaine, can alter the levels ... -
Enhancement of adult hippocampal neurogenesis by spatial memory training and its effect on the maintenance of cocaine-contextual memory
Ávila-Gámiz, Fabiola; Mañas-Padilla, María del Carmen; Ladrón de Guevara-Miranda, David; Gil Rodríguez, Sara; Rodriguez-de-Fonseca, Fernando; Castilla-Ortega, María Estela; Santín-Núñez, Luis Javier[et al.] (2019-10-01)Aims:Modulation of hippocampal memories related with cocaine addiction such as cocaine-context associations could have important clinical implications. It has been asserted that learning-related experiences promote hippocampal ... -
Enhancing adult hippocampal neurogenesis with lysophosphatidic acid: a proposal for erasing cocaine contextual memory
Ladrón de Guevara-Miranda, David; Moreno-Fernández, Román D.; Gil Rodríguez, Sara; Rosell-del-Valle, Cristina; Estivill-Torrús, Guillermo; Serrano, Antonia; Pavón-Morón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2018-06-28)Stimulating adult hippocampal neurogenesis (AHN) has been uncovered as a promising approach in the manipulation of retrograde memories. This work aims to study whether increasing AHN with lysophosphatidic acid (LPA, an ... -
Estudio del cacao como potenciador de la neurogénesis y la función hipocampal en ratones adultos
Introducción: La formación de nuevas neuronas es un fenómeno neuroplástico esencial que se produce en el cerebro adulto, concretamente en el giro dentado del hipocampo (neurogénesis hipocampal adulta, NHA). Numerosos ... -
Experiencia de uso de un cómic (“Arrugas”) como material didáctico en el aula universitaria.
García Borrego, Raúl; Requena-Ocaña, Nerea; Mañas-Padilla, María del Carmen; Castro Zavala, Adriana; Araos Gómez, Pedro Fernando; Gil-Rodríguez, Sara; Caramés-Tejedor, José María; Ortega-Acosta, Sergio; Edelkraut, Lisa; Rivas-Herencia, Eugenio; Castilla-Ortega, María Estela[et al.] (2023)En la actualidad, existen pocas experiencias docentes que incorporen el cómic al entorno universitario. En este trabajo hemos explorado la utilidad de un cómic (“Arrugas”, de Paco Roca) para mejorar el proceso de ... -
Impact of a cocoa-based diet rich in polyphenols on cognitive function, emotional behavior, and adult hippocampal neurogenesis in mice.
Melgar-Locatelli, Sonia; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Razola-Díaz, María del Carmen; Palma-Morales, Marta; Rivera-González, Patricia; Rodríguez-Pérez, Celia; Castilla-Ortega, María Estela[et al.] (2023)Cocoa consumption has long been associated with numerous health benefits due to its rich composition of minerals, fiber, methylxanthines, and polyphenols, particularly flavanols. However, the cognitive effects of cocoa ... -
LPA1/3 receptor antagonist KI16425 as a novel treatment for the neurobehavioural effects of the ethanol
Ladrón de Guevara-Miranda, David; Sánchez-Marín, Laura; Alén, Francisco; Moreno-Fernández, Román D.; García-Fernández, María Inmaculada; Gil Rodríguez, Sara; Gavito, Ana L.; García-Marchena, Nuria; Pedraza-Benítez, María del Carmen; Pavón-Morón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Serrano, Antonia; Castilla-Ortega, María Estela[et al.] (2017-07-24)Aims. The lysophosphatidic acid (LPA) is an ubiquitous lysophospholipid that acts through G-protein coupled receptors (LPA1-6), and it is involved in the modulation of emotional and motivational behaviors. Recent literature ... -
More adult-born dentate gyrus neurons to weaken cocaine-related retrograde memories: an in vivo strategy employing exogenous lysophosphatidic acid
Ladrón de Guevara-Miranda, David; Moreno-Fernández, Román D.; Gil Rodríguez, Sara; Rosell-del-Valle, Cristina; Estivill-Torrús, Guillermo; Serrano, Antonia; Pavón-Morón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2019-10-28)The post-training enhancement of adult hippocampal neurogenesis (AHN) has been receiving growing interest as a potential method to manipulate retrograde memories. Recent hypothesis suggest that the addition of adult-born ... -
Perfil neuropsicológico de paciente con trastorno por uso de sustancias.
Aunque los Trastornos por Uso de Sustancias (TUS) no se han considerado un componente esencial en la etiología de la demencia durante mucho tiempo, el DSM-5 ha introducido recientemente el trastorno neurocognitivo leve y ... -
Persistent drug-associated memories coexist with hippocampal-dependent cognitive decline and altered adult hippocampal neurogenesis in mice withdrawn from cocaine.
Mañas-Padilla, María del Carmen; Gil-Rodríguez, Sara; Sampedro-Piquero, Patricia; Ávila-Gámiz, Fabiola; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2019-10-01)Aims: Using a new animal model (‘chronic’ cocaine-induced conditioned place preference –CPP- paradigm), this work studied whether the long-term maintenance of cocaine-associated memories was concomitant to cognitive ... -
¿Podemos realizar una actividad de discusión grupal en un entorno virtual?
Edelkraut, Lisa; Mañas-Padilla, María del Carmen; Araos Gómez, Pedro Fernando; Pedraza-Benítez, María del Carmen; Castilla-Ortega, María Estela (2021-11-20)Introducción. La adaptación de la docencia universitaria a los entornos virtuales, debido a la pandemia de la COVID-19, puede resultar más compleja en el caso de actividades que requieren una interacción dinámica entre ... -
Proyecto 'Neuropsicoartes’ (Npsicoartes): una experiencia interdisciplinar de aprendizaje basado en proyectos.
Serrano-Ibáñez, Elena Rocío; Ortega-Acosta, Sergio; Mañas-Padilla, María del Carmen; Castro-Zavala, Adriana; Rodríguez-Martínez, María del Carmen; Castilla-Ortega, María Estela[et al.] (2023)Este capítulo de libro relata la experiencia docente del proyecto “Neuropsicoartes (Npsicoartes): mejorando la calidad de vida e integración social de las personas con daño cerebral adquirido”, financiado por la Universidad ... -
Reduction of adult hippocampal neurogenesis modifies brain functional connectivity and enhances cocaine-seeking in mice
Castilla-Ortega, María Estela; Ladrón de Guevara-Miranda, David; Blanco-Calvo, Eduardo; Serrano, Antonia; Pedraz, María; Estivill-Torrús, Guillermo; Pavón-Morón, Francisco Javier; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier[et al.] (2015-09-16)Recently, adult hippocampal neurogenesis has been proposed as a putative neuroplastic mechanism involved in those behavioural processes. In this work, we studied the effect of the inhibition of adult hippocampal neurogenesis ...