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- Psicobiología y Metodología de las Ciencias del Comportamiento - (PMCC)
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Listar PMCC - Contribuciones a congresos científicos por autor "Ávila-Gámiz, Fabiola"
Mostrando ítems 1-12 de 12
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Chronic cocaine exposure during adolescence in mice induces alterations in hippocampal neurogenesis and spatial memory
Gil Rodríguez, Sara; Mañas-Padilla, María del Carmen; Berdugo-Gómez, Mario; Ávila-Gámiz, Fabiola; Romero Zerbo, Silvana Yanina; García-Fernández, María Inmaculada; Santín-Núñez, Luis Javier[et al.] (2022-07)Objectives: Cocaine is the second most widely consumed illicit drug even at early ages, with a prevalence of 2.9% in Spain in the 14-18 age group. Chronic consumption produces several cognitive-behavioral and hippocampal ... -
Cognitive impairment and persistent changes in exploration and hyperactivity in mice after withdrawn from chronic cocaine
Mañas-Padilla, María del Carmen; Ávila-Gámiz, Fabiola; Gil Rodríguez, Sara; Ladrón de Guevara-Miranda, David; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2021)Lasting neurobehavioral adaptations such as cognitive decline are induced by chronic cocaine exposure in animal models. However, persistent changes in motor and exploratory responses are rarely reported. In this study, ... -
Effect of a spatial memory training on the persistence of cocaine-contextual memory
Ávila-Gámiz, Fabiola; Mañas-Padilla, María del Carmen; Ladrón de Guevara-Miranda, David; Gil Rodríguez, Sara; Rodriguez-de-Fonseca, Fernando; Castilla-Ortega, María Estela; Santín-Núñez, Luis Javier[et al.] (2019-07-03)Modulation of hippocampal memories related with cocaine addiction such as cocaine-context associations could have important clinical implications. It has been shown that learning-related experiences are potent modulators ... -
Effects of sequential exposure to physical exercise and cognitive training on hippocampal neurogenesis in mice
Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Mullor-Vigo, Rosa; Pérez-Berlanga, José Manuel; Zambrana-Infantes, Emma; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2022-07-13)AIMS: Physical exercise and cognitive training hippocampal dependent tasks are known to enhance adult hippocampal neurogenesis (AHN). Here we aimed to evaluate the effect of either a moderate-intensity exercise protocol, ... -
Enhancement of adult hippocampal neurogenesis by spatial memory training and its effect on the maintenance of cocaine-contextual memory
Ávila-Gámiz, Fabiola; Mañas-Padilla, María del Carmen; Ladrón de Guevara-Miranda, David; Gil Rodríguez, Sara; Rodriguez-de-Fonseca, Fernando; Castilla-Ortega, María Estela; Santín-Núñez, Luis Javier[et al.] (2019-10-01)Aims:Modulation of hippocampal memories related with cocaine addiction such as cocaine-context associations could have important clinical implications. It has been asserted that learning-related experiences promote hippocampal ... -
Influence of neurogenic improvement strategies on extinction and reinstatement of cocaine-induced conditioned place preference
Mullor-Vigo, Rosa; Ávila-Gámiz, Fabiola; Zambrana-Infantes, Emma; Mañas-Padilla, María del Carmen; Gil Rodríguez, Sara; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David; Santín-Núñez, Luis Javier[et al.] (2022)AIMS: Modulation of adult hippocampal neurogenesis (AHN) has been shown to influence the maintenance of drug-context associations. We aimed to study whether the enhancement of AHN by using a water maze spatial learning ... -
Neuroprotective effects of insulin-like growth factor II in a mouse model of Parkinson's disease
Ladrón de Guevara-Miranda, David; Martín-Montáñez, Elisa; Valverde, Nadia; Lara, Estrella; Romero Zerbo, Silvana Yanina; Millón-Peñuela, Carmelo; Boraldi, Federica; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Garrido-Gil, Pablo; Labandeira-García, José Luis; Santín-Núñez, Luis Javier; Pavía-Molina, José; García-Fernández, María Inmaculada[et al.] (2022-07-20)Progressive degeneration of the nigrostriatal dopaminergic pathway is a core, currently irreversible pathological hallmark of Parkinson’s disease (PD) that leads to a variety of motor and non-motor symptoms. Here, we aimed ... -
Persistent drug-associated memories coexist with hippocampal-dependent cognitive decline and altered adult hippocampal neurogenesis in mice withdrawn from cocaine.
Mañas-Padilla, María del Carmen; Gil-Rodríguez, Sara; Sampedro-Piquero, Patricia; Ávila-Gámiz, Fabiola; Rodriguez-de-Fonseca, Fernando; Santín-Núñez, Luis Javier; Castilla-Ortega, María Estela[et al.] (2019-10-01)Aims: Using a new animal model (‘chronic’ cocaine-induced conditioned place preference –CPP- paradigm), this work studied whether the long-term maintenance of cocaine-associated memories was concomitant to cognitive ... -
Pharmacogenetic inhibition of the infralimbic cortex promotes reinstatement of cocaine-context memories in mice.
Pérez-Cano, Ana María; Ávila-Gámiz, Fabiola; Pérez Berlanga, José Manuel; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David (2023)Relapse is one of the main problems concerning treatment of cocaine use disorder. It have been suggested that the infralimbic cortex (IL), a division of the medial prefrontal cortex, is involved in extinction and reinstatement ... -
The presence of a social stimulus reduces cocaine seeking in a place preference conditioning paradigm.
Sampedro-Piquero, Patricia; Ávila-Gámiz, Fabiola; Moreno-Fernández, Román D.; Santín-Núñez, Luis Javier (2019-09-26)BACKGROUND: One challenge in the treatment of substance use disorders is to re-engage the interest toward non-drug-related activities. Among these activities, social interaction has had a prominent role due to its positive ... -
Spatial training in the Water Maze facilitates extinction and prevents reinstatement of cocaine-induced Conditioned Place Preference
Ávila-Gámiz, Fabiola; Mañas-Padilla, María del Carmen; Gil Rodríguez, Sara; Zambrana-Infantes, Emma; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2021)Manipulation of adult hippocampal neurogenesis has been shown to affect the establishment of cocaine-context associations as well as extinction learning and reinstatement of these maladaptive memories. In this work, we ... -
The infralimbic cortex and the hippocampal CA1-Subiculum are functionally involved in the extinction of cocaine-context associationes in mice.
Pérez Berlanga, José Manuel; Ávila-Gámiz, Fabiola; Pérez-Cano, Ana María; Mullor-Vigo, Rosa María; Santín-Núñez, Luis Javier; Ladrón de Guevara-Miranda, David[et al.] (2023)Cocaine abuse is a health and social problem worldwide. Treatment seeking for cocaine use disorder is on the rise, and relapse prevention remains as a primary goal. Interventions based on extinction of cocaine-related ...