Listar Química Orgánica - (QO) por título
Mostrando ítems 1-20 de 121
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A Peptide/Fullerene Hybrid for Multivalent Recognition of E-Selectin
(2022-06-28)Molecular recognition through ligand-receptor interactions is a very important mechanism for metastatic processes. Among all of them, multivalent protein-carbohydrate interactions play a fundamental role in tumor ... -
Adsorbatos isoquinolínicos y benzazepínicos: síntesis e incorporación a superficies de silicio y nanopartículas
(UMA Editorial, 2019)La mayoría de los productos farmacéuticos aprobados por la FDA presentan en su estructura átomos de nitrógeno. De hecho, más de la mitad de ellos incluyen un heterociclo de nitrógeno. Entre los heterociclos de nitrógeno ... -
Allergic reactions to β-lactam antibiotics: chemical approaches for improving in vitro diagnosis
(UMA Editorial, 2018-10-16)Drug hypersensitivity reactions are a significant public health problem with important consequences on patient health and healthcare costs. It has been reported that only a low percentage of initial cases suspected of ... -
Aminonaphtamiline-squaraine dyad: photophysical properties and bioimaging application
(2018-09-19)Squaraines is an important part of the cyanine family which have high extinction coefficients, sharp absorption bands, and intense fluorescence spectra in the red and near infrared region in solution.[1] The unique electronic ... -
Aminonaphthalimide-squaraine dyads: photophysical properties and bioimaging application
(2021)Squaraines is an important part of the cyanine family which have high extinction coefficients, sharp absorption bands, and intense fluorescence spectra in the red and near infrared region in solution.[1] The unique electronic ... -
Asymmetric total synthesis of alkaloid natural products without external chiral sources
(2018-03-22)The chirality of a starting material having a chiral sp3-carbon can be preserved under some circumstances in the reaction product even though the reaction proceeds at the chiral carbon as a reaction center through reactive ... -
Back to the Future - The Scientific Exploration of An Ancient Medicinal Plant
(2016-10-13)Alkaloids are active compounds found in plants. In the conference has been reviewed new sceletium alkaloids isolated from african plants. -
Benzotriazole-based multidonor-acceptor systems as attractive two-photon absorption dye platforms
(Elsevier, 2022-02-03)Pyrazine-decorated benzotriazole cores allow the orthogonal combination of two dipolar systems within a single molecule. A series of this type of derivatives was synthesized and their photophysical features were studied. ... -
Carbazole-based Diradicals for Dynamic Covalent Chemistry
(2020-01-29)Dynamic covalent chemistry (DCC) is focused on the creation of structural scaffolds based on chemical components that interact through strong but reversible bonds. In fact, dynamic covalent bonds receive lot of attention ... -
Combinando enzimas y complejos organometálicos: nuevos biohibridos como catalizadores altamente eficientes
(2019-01-21)Los catalizadores de metales de transición y las enzimas poseen propiedades únicas y a menudo complementarias que los han convertido en herramientas importantes para la síntesis química. La combinación de un complejo ... -
Comparative study of dopaminergic activity of tetrahydro-1H-[3]-benzazepines and their precursors
(2016-10-14)The discovery of the tetrahydro-1H-[3]-benzazepine SCH23390 [1], represented one of the most important advances in the study of dopaminergic receptors due to their behavior as a selective D1 receptor antagonist. The high ... -
Controlling the aggregation of planar photosensitizers and electroluminescent materials
(2014-12-22)Aggregation of planar chromophores greatly affects their photophysical performance. It is possible to avoid the aggregation of phthalocyaninates by axially binding them to the surface of aluminosilicates. We have recently ... -
Crossing the Valley of Death in Drug Discovery
(2016-11-10)Diseño y desarrollo de nuevos fármacos contra el cáncer actuando como inhibidores de quinasas -
Dendrímeros Antigénicos fijados sobre nanopartículas para diagnostico in vitro de alergia a fármacos
(UMA Editorial, 2022-07-18)Las Reacciones Adversas a Fármacos (RAF) constituyen actualmente un problema sanitario importante debido al gran desconocimiento sobre los mecanismos por los que se desencadenan, lo que se traduce en una ausencia de pruebas ... -
Dendrímeros antigénicos sobre partículas de sílica para determinar IgE específicas de antibióticos betalactámicos
(2022)Los inmunoensayos empleados para el diagnóstico in vitro de alergias a antibióticos betalactámicos actualmente presentan una limitada sensibilidad y pobre especificidad, además de no estar disponibles de forma comercial ... -
Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic
(2013-09-25)The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ... -
Desarrollo de un prototipo simulador del tracto gastrointestinal mediante reactores químicos automatizados
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)El prototipo descrito en esta Tesis Doctoral se emplea para realizar la simulación in vitro del tracto gastrointestinal. Esta simulación se lleva a cabo en las tres fases que se describen a continuación: simulación de ... -
Design and synthesis of nanostructures to study the specific molecular recognition and effector Cell activation in the immunological responses to amoxicillin
(UMA Editorial, 2022)Amoxicillin (AX) is the penicillin currently regarded as the main culprit in eliciting allergic reactions. According to hapten hypothesis, AX immunogenicity can only be gained by forming covalent conjugates with proteins. ... -
Design and synthesis of new dendrons for biomedical applications
(2020-03-30)Dendrons are excellent multifunctional platforms for many different applications. In particular, the development of multivalent molecular nanostructures, with a well-defined size and shape, has an enormous interest in the ... -
Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications
(2018-11-15)Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in ...