Listar Química Orgánica - (QO) por título
Mostrando ítems 7-26 de 121
-
Back to the Future - The Scientific Exploration of An Ancient Medicinal Plant
(2016-10-13)Alkaloids are active compounds found in plants. In the conference has been reviewed new sceletium alkaloids isolated from african plants. -
Benzotriazole-based multidonor-acceptor systems as attractive two-photon absorption dye platforms
(Elsevier, 2022-02-03)Pyrazine-decorated benzotriazole cores allow the orthogonal combination of two dipolar systems within a single molecule. A series of this type of derivatives was synthesized and their photophysical features were studied. ... -
Carbazole-based Diradicals for Dynamic Covalent Chemistry
(2020-01-29)Dynamic covalent chemistry (DCC) is focused on the creation of structural scaffolds based on chemical components that interact through strong but reversible bonds. In fact, dynamic covalent bonds receive lot of attention ... -
Combinando enzimas y complejos organometálicos: nuevos biohibridos como catalizadores altamente eficientes
(2019-01-21)Los catalizadores de metales de transición y las enzimas poseen propiedades únicas y a menudo complementarias que los han convertido en herramientas importantes para la síntesis química. La combinación de un complejo ... -
Comparative study of dopaminergic activity of tetrahydro-1H-[3]-benzazepines and their precursors
(2016-10-14)The discovery of the tetrahydro-1H-[3]-benzazepine SCH23390 [1], represented one of the most important advances in the study of dopaminergic receptors due to their behavior as a selective D1 receptor antagonist. The high ... -
Controlling the aggregation of planar photosensitizers and electroluminescent materials
(2014-12-22)Aggregation of planar chromophores greatly affects their photophysical performance. It is possible to avoid the aggregation of phthalocyaninates by axially binding them to the surface of aluminosilicates. We have recently ... -
Crossing the Valley of Death in Drug Discovery
(2016-11-10)Diseño y desarrollo de nuevos fármacos contra el cáncer actuando como inhibidores de quinasas -
Dendrímeros Antigénicos fijados sobre nanopartículas para diagnostico in vitro de alergia a fármacos
(UMA Editorial, 2022-07-18)Las Reacciones Adversas a Fármacos (RAF) constituyen actualmente un problema sanitario importante debido al gran desconocimiento sobre los mecanismos por los que se desencadenan, lo que se traduce en una ausencia de pruebas ... -
Dendrímeros antigénicos sobre partículas de sílica para determinar IgE específicas de antibióticos betalactámicos
(2022)Los inmunoensayos empleados para el diagnóstico in vitro de alergias a antibióticos betalactámicos actualmente presentan una limitada sensibilidad y pobre especificidad, además de no estar disponibles de forma comercial ... -
Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic
(2013-09-25)The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ... -
Desarrollo de un prototipo simulador del tracto gastrointestinal mediante reactores químicos automatizados
(Universidad de Málaga, Servicio de Publicaciones y Divulgación Científica, 2014)El prototipo descrito en esta Tesis Doctoral se emplea para realizar la simulación in vitro del tracto gastrointestinal. Esta simulación se lleva a cabo en las tres fases que se describen a continuación: simulación de ... -
Design and synthesis of nanostructures to study the specific molecular recognition and effector Cell activation in the immunological responses to amoxicillin
(UMA Editorial, 2022)Amoxicillin (AX) is the penicillin currently regarded as the main culprit in eliciting allergic reactions. According to hapten hypothesis, AX immunogenicity can only be gained by forming covalent conjugates with proteins. ... -
Design and synthesis of new dendrons for biomedical applications
(2020-03-30)Dendrons are excellent multifunctional platforms for many different applications. In particular, the development of multivalent molecular nanostructures, with a well-defined size and shape, has an enormous interest in the ... -
Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications
(2018-11-15)Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in ... -
Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition
(2014-06-12)Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ... -
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells
(Real Sociedad Española de Química, 2018-06-20)Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS ... -
Development of Novel Nanobiosensors for Diagnostics of Adverse Drug Reactions.
(UMA Editorial, 2023)Amoxicilina es uno de los antibioticos del grupo de penicilinas más usados. Penicilinas son el grupo de antibioticos que provocan más reaciones alérgicas entre todos los medicamentos. Diagnóstico correcto es necesario para ... -
Diastereoselective C-alkylation of aldimines, derived from chiral alpha-carbon heteroatom substituted aldehydes, with triethylborane. Application to the synthesis of benzylisoquinolines
(Royal Society of Chemistry, 2023-03-13)The one-pot reaction of a chiral aldehyde, p-methoxyaniline or p-fluoroaniline, and triethylborane produces the corresponding alkylated chiral amine with high yields and distereoisomeric ratios. Stereocontrol is induced ... -
Diastereoselective synthesis of chiral amines by imines alkylation
(2013-10-03)En esta comunicación se aborda la síntesis de aminas quirales utilizando como agente alquilante trietilborano. -
Direct characterization of functional materials by haptenized fluorescent dendrimers for in vitro allergic drug diagnose
(2020-10-01)β-lactams are the most widely drug prescribed against infections, but they are the most commonly reported medication allergy too. A correct diagnosis of these allergic reactions is crucial to avoid rejecting them by other ...