Listar Química Orgánica - (QO) por título
Mostrando ítems 41-60 de 121
-
Inorganic nanoparticles: Possible solution for different problems
(2017-09-15)Formation and Controlled Growth of Bismuth Titanate Phases into Mesoporous Silica Nanoparticles: An Efficient Self-Sealing Nanosystem for UV Filtering in Cosmetic Formulation. Biocompatible tailored zirconia mesoporous ... -
Intramolecular [3+2] cycloaddition of azido-unsaturated esters derived of monosaccharides
(2013-11-05)Iminosugars have been shown to be very potent inhibitors of glycosidases and glycolsyltransferases. Due to their ability to resemble the transition states of the sugars involved in these processes, a variety of m onocyclic ... -
Intramolecular [3+2] Cycloaddition of Fused Azolo-Azepanes from Azido Monosaccharides Derivatives
(Centro Investigaciones Biológicas, 2016)Síntesis de bicíclicos compuestos empleando epoxiamidas como material de partida. Obtención de tetrazolo azepanos con posible actividad biológica. -
Isolation of Mycosporine-like Amino Acids from Red Macroalgae and a Marine Lichen by High-Performance Countercurrent Chromatography: A Strategy to Obtain Biological UV-Filters.
(MDPI, 2023-06-10)Marine organisms have gained considerable biotechnological interest in recent years due to their wide variety of bioactive compounds with potential applications. Mycosporine-like amino acids (MAAs) are UV-absorbing secondary ... -
Lipid and Janus nanoparticles for active delivery
(2014-06-12)The following synthesis is based on the paper „Production of large quantities of „Janus“ nanoparticles using wax-in-water emulsions“ published by Ravaine et al.[1]In two beakers, 0.2 g of the synthesized silica particles ... -
Magnetically active pNIPAM nanosystems as temperature-sensitive biocompatible structures for controlled drug delivery
(Taylor and Francis, 2020-04-19)Here, temperature-sensitive hybrid poly(N-isopropylacrylamide) (pNIPAM) nanosystems with magnetic response are synthesised and investigated for controlled release of 5-fluorouracil (5FU) and oxaliplatin (OXA). Initially, ... -
Managing with (fluorescent)-biomimetic dendrimers
(2017-06-30)Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes. Diagnosis via specific interactions with target proteins is one of the objectives that has been given more ... -
El mar como fuente de nuevos fármacos
(2015-09-02)Se describe el proceso de descubrimiento y desarrollo de nuevos fármacos por la empresa PharmaMar a partir de productos naturales de origen marino aislados de organismos de muy diversos tipos. Para ello, se describe el ... -
Modificación química de superficies para aplicaciones biomédicas
(2015-06-09)En el caso de las nanopartículas esta superficie concentra una gran cantidad de átomos, hasta tal punto que por ejemplo en una nanopartícula de Fe3O4 de 5 nm de diámetro presenta más del 35% de los átomos se encuentran ... -
Muraymycin-derived nucleoside-peptide antibiotics: potential lead structures for novel antimicrobial agents
(2015-10-08)En esta conferencia se describe el mecanismo de acción de una nueva clase de antibióticos tipo nucleósidos denominados muraimicinas, caracterizados por la presencia de una cadena peptídica unida al fragmento nucleosídico. ... -
n-Tuples on Scaffold Diversity Inspired by Drug Hybridisation to Enhance Drugability: Application to Cytarabine
(MDPI, 2023-12-13)A mathematical concept, n-tuples are originally applied to medicinal chemistry, especially with the creation of scaffold diversity inspired by the hybridisation of different commercial drugs with cytarabine, a synthetic ... -
NanoFN10: A High-Contrast Turn-On Fluorescence Nanoprobe for Multiphoton Singlet Oxygen Imaging.
(MDPI, 2023-05-09)An “off-on” fluorescent nanoprobe for near-infrared multiphoton imaging of singlet oxygen has been developed. The nanoprobe comprises a naphthoxazole fluorescent unit and a singlet-oxygen-sensitive furan derivative attached ... -
Nanopartículas híbridas Fe3O4@pNIPAM y Ag2S/Ag para aplicaciones en nanomedicina
(UMA Editorial, 2022)Esta Tesis Doctoral se engloba dentro del ámbito de la nanomedicina mediante el desarrollo y la caracterización de nanopartículas con potencial uso biomédico para el diagnóstico y tratamiento de enfermedades. Por un ... -
Nanopartículas metalo-orgánicas: síntesis, caracterización y aplicación a la vehiculización de Paclitaxel, 5-Fluorouracilo y Doxorrubicina
(UMA Editorial, 2019-11)La síntesis y optimización de sistemas de nanopartículas en medicina muestra interés debido a las características que presentan: i) son sensibles a estímulos externos, como el pH, la temperatura, la luz etc. y ii) la alta ... -
Nanoscale biocompatible structures generated from fluorinated tripodal phenylenes on gold nanoprisms
(Wiley, 2022-03-09)Modification of gold substrates with a stable, uniform and ultrathin layer of biocompatible materials is of tremendous interest for the development of bio-devices. We present the fabrication of hybrid systems consisting ... -
New Approaches in the Manufacture of Biomaterials for Betalactam Allergic Diagnose
(2019-09-11)Betalactams are the most widely utilized drugs against infections but are the primary cause of allergic reactions to antibiotic drugs. REF1 An accurate diagnosis of these allergic reactions to betalactams is crucial to ... -
New Approaches to Oxirane Containing Natural Products: Stereoselective Total Synthesis of the Antitumor Agents Gummiferol and Depudecin
(2015-07-30)La comunicación presenta la síntesis total de productos naturales con actividad antitumoral caracterizados estructuralmente por la presencia de anillos de oxirano. Para ello se empleó una nueva metodología de epoxidación ... -
New bodipy dyads for two-photons fluorescence imaging in cells
(2016-09-13)Fluorescent probes are essential tools for studying biological systems. The last decade has witnessed particular interest in the development of two-photon excitable probes, due to their advantageous features in tissue ... -
New indolium fluorofores for two-photon absortion (2PA) bioimaging applications
(2016)The development of organic materials with 2PA has attracted intensive attention in the past two decades [1]. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section (σ2PA) ... -
New molecules based indolium for two-photon absortion bioimaging applications
(Universidad de Extremadura, 2017)The development of organic materials with 2PA has attracted intensive attention in the past two decades. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section and good ...