Listar Química Orgánica - (QO) por fecha de publicación
Mostrando ítems 41-60 de 121
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Titanocenos, antraquinonas, flavonoides y polimeros. RMN como denominador comun
(2016-12-19)Se analizan diversos casos de identificacion productos naturales y de caracterizacion de mecanismos de reaccion mediante resonancia magnetica nuclear -
Síntesis de moléculas híbridas, inspiradas en la genómica, como antifúngicos contra el hongo fitopatógeno Botrytis cinerea
(2016-12-20)En esta conferencia se han presentado los últimos resultados en la investigación del grupo que dirige el Prof. Isidro González para el diseño de nuevos agentes antifúngicos frente al hongo Botrytis cinerea que resulta ... -
New molecules based indolium for two-photon absortion bioimaging applications
(Universidad de Extremadura, 2017)The development of organic materials with 2PA has attracted intensive attention in the past two decades. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section and good ... -
Nuevas Reacciones Catalíticas de Ciclación y de Acoplamiento
(2017-03-27)La conferencia incluye aspectos modernos de la química catalítica como, por ejemplo, las reacciones de acoplamiento de Suzuki, Heck, Sonogashira y Buchwald Hartwig. Un aspecto importante es la regioselectividad de estas ... -
Synthesis and applications in biomedicine of new dendrimeric structures
(2017-06-20)Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density ... -
Managing with (fluorescent)-biomimetic dendrimers
(2017-06-30)Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes. Diagnosis via specific interactions with target proteins is one of the objectives that has been given more ... -
Two-Photon Fluorescence As Tool For Imaging In Cells
(2017-06-30)Fluorescent probes are essential tools for studying biological systems. The last decade has witnessed particular interest in the development of two-photon excitable probes, due to their advantageous features in tissue ... -
Synthesis of Molecular Tripods Functionalized with Thioacetate Groups. Model Molecules for Gold Substrates Nanostructuration
(2017-07-11)Self-assembled monolayers (SAMs) of thiols on gold surfaces have attracted widespread interest as they can serve as structural and/or functional parts of biosensors, drug-delivery systems, electronics devices, among other ... -
Synthesis and study of biological activity of tetrahydro-1H-[3]-benzazepines
(2017-07-20)The 3-Benzazepines are an important class of compounds in drug discovery due to their biological activity such as analgesic, antihypertensive or anticancer properties as well as dopaminergic or antidopaminergic activity. ... -
Synthesis of bioactive compounds. Studies of their attachment to nanoparticles
(2017-07-20)The 1-aryl tetrahydroisoquinolines have attracted great attention in medicinal chemistry due to their biological activity. These compounds present antitumor, anti-HIV and antibacterial activities. Several analogues of ... -
Synthesis of New Analogues of the Bengamides: Peptidyl Bengamides and Molecular Probes
(2017-07-20)Isolated from sponges of the Jaspidae family, first members where discovered in 1986. The bengamides represent an interesting and unprecedented family of natural products that displayed striking antitumor activities [1]. ... -
Total synthesis of depudecin and analogues via an olefin cross-metathesis based strategy
(2017-07-20)(-)-Depudecin (1), isolated from the culture broths of the fungus Alternaria brassicicola [1], has been identified as a selective inhibitor of histone deacetylases (HDAC) with an IC50 in the low μM range. In contrast to ... -
Inorganic nanoparticles: Possible solution for different problems
(2017-09-15)Formation and Controlled Growth of Bismuth Titanate Phases into Mesoporous Silica Nanoparticles: An Efficient Self-Sealing Nanosystem for UV Filtering in Cosmetic Formulation. Biocompatible tailored zirconia mesoporous ... -
Hybrid pH-Responsive Au@p4VP Microgels as Platform for Selective SERS Analysis
(2017-09-21)We present the synthesis a of pH-responsive core@shell hybrid microgel. This colloidal system is formed by a 55 nm Au core individually covered by a polymeric pH-sensitive shell of poly(4-vinylpyridine), that we denote as ... -
Diseño y síntesis de nuevos dendrímeros y dendrones. Aplicaciones en regeneración tisular
(2018-03-06)Los dendrímeros han generado un enorme interés debido a su particular estructura ramificada y su multivalencia. La extensa investigación que se ha llevado a cabo sobre este tipo de macromoléculas ha demostrado la naturaleza ... -
Diseño y síntesis de nuevos dendrímeros
(2018-03-06)Los dendrímeros son excelentes plataformas multifuncionales para una gran cantidad de diferentes aplicaciones. En particular, el desarrollo de nanoestructuras moleculares multivalentes, con tamaño y forma bien definida, ... -
Diseño y síntesis de nuevos dendrones para aplicaciones biomédicas
(2018-03-06)Los dendrímeros han sido empleados en una gran variedad de aplicaciones, entre las que destacan las del campo de la biomedicina. Estas macromoléculas multivalentes ofrecen la posibilidad de incorporar múltiples funcionalidades ... -
Tripodal penta(p-phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces.
(Elsevier, 2018-03-22)Here we report the optimization on the covalent grafting methodology of a tripod-shaped penta(p-phenylene), 1, on alkynyl-terminated silicon surfaces, and the incorporation of an active theophylline derivative, 2, for the ... -
Asymmetric total synthesis of alkaloid natural products without external chiral sources
(2018-03-22)The chirality of a starting material having a chiral sp3-carbon can be preserved under some circumstances in the reaction product even though the reaction proceeds at the chiral carbon as a reaction center through reactive ... -
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells
(Real Sociedad Española de Química, 2018-06-20)Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS ...