Listar QO - Artículos por título
Mostrando ítems 7-18 de 18
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Magnetically active pNIPAM nanosystems as temperature-sensitive biocompatible structures for controlled drug delivery
(Taylor and Francis, 2020-04-19)Here, temperature-sensitive hybrid poly(N-isopropylacrylamide) (pNIPAM) nanosystems with magnetic response are synthesised and investigated for controlled release of 5-fluorouracil (5FU) and oxaliplatin (OXA). Initially, ... -
n-Tuples on Scaffold Diversity Inspired by Drug Hybridisation to Enhance Drugability: Application to Cytarabine
(MDPI, 2023-12-13)A mathematical concept, n-tuples are originally applied to medicinal chemistry, especially with the creation of scaffold diversity inspired by the hybridisation of different commercial drugs with cytarabine, a synthetic ... -
NanoFN10: A High-Contrast Turn-On Fluorescence Nanoprobe for Multiphoton Singlet Oxygen Imaging.
(MDPI, 2023-05-09)An “off-on” fluorescent nanoprobe for near-infrared multiphoton imaging of singlet oxygen has been developed. The nanoprobe comprises a naphthoxazole fluorescent unit and a singlet-oxygen-sensitive furan derivative attached ... -
Nanoscale biocompatible structures generated from fluorinated tripodal phenylenes on gold nanoprisms
(Wiley, 2022-03-09)Modification of gold substrates with a stable, uniform and ultrathin layer of biocompatible materials is of tremendous interest for the development of bio-devices. We present the fabrication of hybrid systems consisting ... -
Photophysical properties and bioimaging application of an aminonaphthalimide-squaraine non-conjugated system
(ELSEVIER, 2022-02-15)An aminonaphthalimide-squaraine non-conjugated system was designed and synthetized with the purpose of preparing fluorescent molecule in the 650–700 nm region that could operate via energy transfer (ET) between covalently ... -
Slightly congested amino terminal dendrimers. The synthesis of amide-based stable structures on a large scale.
(Royal Society of Chemistry, 2021-08-17)Nowadays, amino terminal dendrimers are appealing materials for biological applications due to their multivalence and the versatile conjugation of the amino groups. However, the high reactivity of these terminal groups can ... -
SPION Nanoparticles for Delivery of Dopaminergic Isoquinoline and Benzazepine Derivatives.
(Elsevier, 2022-06-27)Superparamagnetic iron nanoparticles (SPIONs) have become one of the most useful colloidal systems in nanomedicine. We report here the preparation of new hybrid core@shell systems based on SPION nanoparticles coated with ... -
Synthesis and dopaminergic activity of a series of new 1-aryl tetrahydroisoquinolines and 2-substituted 1-aryl-3-tetrahydrobenzazepines.
(Elsevier, 2018-07-05)A series of new 1-aryl-6,7-dihydroxy tetrahydroisoquinolines with several substitution patterns in the 1-aryl group at C-1 were prepared in good yields. The influence of each substituent on the affinity and selectivity for ... -
The Development of the Bengamides as New Antibiotics against Drug-Resistant Bacteria
(IOAP-MPDI, 2022-05-31)The bengamides comprise an interesting family of natural products isolated from sponges belonging to the prolific Jaspidae family. Their outstanding antitumor properties, coupled with their unique mechanism of action and ... -
Transition metal-free [2,3]-sigmatropic rearrangement in the reaction of sulfur ylides with allenoates
(RSC, 2023-08)An unprecedented transition metal free [2,3]-sigmatropic rearrangement involving stabilized sulfur ylides and allenoates has been thoroughly established. The scope and utility of this reaction have been extensively studied ... -
Tripod-shaped molecules: Synthesis and immobilization on Au(1 1 1) substrates.
(2018-11-09)We describe design and synthesis of novel tripod-shaped molecules that are potentially capable of monomolecular assembly on noble metal substrates, maintaining, due to their rigidity and specific geometry, the orientation ... -
Tripodal penta(p-phenylene) for the biofunctionalization of alkynyl-modified silicon surfaces.
(Elsevier, 2018-03-22)Here we report the optimization on the covalent grafting methodology of a tripod-shaped penta(p-phenylene), 1, on alkynyl-terminated silicon surfaces, and the incorporation of an active theophylline derivative, 2, for the ...