Listar QO - Contribuciones a congresos científicos por título
Mostrando ítems 37-55 de 55
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Synthesis and applications in biomedicine of new dendrimeric structures
(2017-06-20)Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density ... -
Synthesis and biological activity of a new class of antitumor cyclopeptides based on the solomonamides
(2018-10-15)Solomonamides A (1) and B (2) are novel natural products recently isolated from the marine sponge Theonella swinhoei [1]. Preliminary structural studies revealed an unprecedented cyclic peptide type structure. Interestingly, ... -
Synthesis and Biological Evaluation of Depudecin Analogues
(2019-09-18)(-)-Depudecin (1) (Figure 1), isolated from the culture broths of the fungus Alternaria brassicicola,1 and later, from the weed pathogen Nimbya scirpicola,2 has been identified as a selective inhibitor of histone deacetylases ... -
Synthesis and Biomedical aplications of BAPAD: Bisaminoalkylpolyamide Dendrimers
(2014-02-06)A new class of Dendrimeric Systems (Dendrimers and Dendrons) and the study of their properties in molecular recognition processes are presented. These Dendrimers (BAPAD: BisAminoalkylPolyAmideDendrimers), are designed to ... -
Synthesis and study of biological activity of tetrahydro-1H-[3]-benzazepines
(2017-07-20)The 3-Benzazepines are an important class of compounds in drug discovery due to their biological activity such as analgesic, antihypertensive or anticancer properties as well as dopaminergic or antidopaminergic activity. ... -
Synthesis of bioactive compounds. Studies of their attachment to nanoparticles
(2017-07-20)The 1-aryl tetrahydroisoquinolines have attracted great attention in medicinal chemistry due to their biological activity. These compounds present antitumor, anti-HIV and antibacterial activities. Several analogues of ... -
Synthesis of fluorescent BAPAD dendrimeric structrures for biomedical applications
(2014-02-03)In this work, we present the synthesis and characterization of BAPAD1 fluorescent Dendrimeric-Antigens (DeAn), to study the dendritic cell maturation as a test to detect drug allergy reactions. Recently our research group ... -
Synthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cells
(Servicio de Publicaciones de la Universidad de Huelva, 2016)A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide ... -
Synthesis of fused tetrazolo iminosugars from azido monosaccharide derivatives
(Universidad de la Rioja, 2014)Synthesis of fused tetrazolo iminosugars from azido monosaccharide derivatives -
Synthesis of Molecular Tripods Functionalized with Thioacetate Groups. Model Molecules for Gold Substrates Nanostructuration
(2017-07-11)Self-assembled monolayers (SAMs) of thiols on gold surfaces have attracted widespread interest as they can serve as structural and/or functional parts of biosensors, drug-delivery systems, electronics devices, among other ... -
Synthesis of New Analogues of the Bengamides to encapsulate in magnetic nanoparticles
(2019-05-15)The development and identification of new antitumoral has become a research area of great interest and maximum priority due to secondary effects of current antitumoral and the appearance of tumours resistant to these agents. ... -
Synthesis of New Analogues of the Bengamides: Peptidyl Bengamides and Molecular Probes
(2017-07-20)Isolated from sponges of the Jaspidae family, first members where discovered in 1986. The bengamides represent an interesting and unprecedented family of natural products that displayed striking antitumor activities [1]. ... -
Synthesis of new bengamide analogues and encapsulation into thermo-responsive magnetic nanoparticles
(2019-09-16)The development and identification of new antitumoral drugs has become a research area of great interest and maximum priority. Firstly, to overcome the secondary effects frequently shown by current antitumorals and, secondly, ... -
Synthesis of the Macrocylic Core of the Solomonamides, a New Class of Cyclopeptides of Marine Origin
(2016-09-29)Se describe estudios sintéticos dirigidos hacia la síntesis total de solomonamides, una nueva clase de ciclopéptidos de origen marino que presentan interesantes propiedades biológicas. La aproximación sintética se basó en ... -
Thermorresponsive magnetic nanoparticles as target drug delivery for cancer treatment
(2019-05-15)In this research, temperature sensitive microgels with magnetic core for controlled release of 5-fluoruracil was synthesized. Magnetic nanoparticles (Fe3O4) were prepared by coprecipitation method and the surface was ... -
Total synthesis of depudecin and analogues via an olefin cross-metathesis based strategy
(2017-07-20)(-)-Depudecin (1), isolated from the culture broths of the fungus Alternaria brassicicola [1], has been identified as a selective inhibitor of histone deacetylases (HDAC) with an IC50 in the low μM range. In contrast to ... -
Tripod-shaped penta (p-phenylene)s for the functionalization of silicon surfaces
(2016-03-31)In order to obtain nanostructured thin films to be used in biosensor devices, several chemical functionalization methods have been developed, such as Click chemistry or Suzuki carbon-carbon coupling reactions on surfaces.1 ... -
Tuning pKa in new molecules based on indolines for two-photon absorption bioimaging applications
(Real Sociedad Española de Química, 2018-06-20)Fluorescence-based biosensors have become essential tools for modern biology, allowing real-time monitoring of biological processes within living cells. The differences between pH play a significant role in multiple ... -
Two-Photon Fluorescence As Tool For Imaging In Cells
(2017-06-30)Fluorescent probes are essential tools for studying biological systems. The last decade has witnessed particular interest in the development of two-photon excitable probes, due to their advantageous features in tissue ...