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      • “Off-on” two-photon indolenine probes for pH bioimaging 

        Benitez-Martin, Carlos; Guadix, Juan Antonio; Pearson, John R.; Najera-Albendin, Francisco; Perez-Pomares, Jose Maria; [et al.] (2019-10-25)
        Fluorescence-based biosensors have become an indispensable tool in modern biology. These molecules can be used to monitor processes inside living cells and in real-time. The control of the pH is crucial in multiple biological ...
      • One and two-photons excitation of aminonaphthalimide–bodipy dyads: biological application 

        Vida-Pol, Yolanda (2014-07-25)
        Boron dipyrromethene (BODIPY) dyes are commonly commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry. However, the generally very small Stokes shifts of BODIPY dyes ...
      • Preparation, photophysical properties and cell image of Naphthalimide-based fluorescent nanostructures for biomedical applications: BAPAD dendrimeric antigens and silica nanoparticles 

        Mesa, Pablo; Collado, Daniel; Vida-Pol, Yolanda; Najera-Albendin, Francisco; Perez-Inestrosa, Ezequiel (2014-07-17)
        We present here the synthesis and characterization of BAPAD [1] fluorescent Dendrimeric-Antigens (DeAn), to be applied in basophil activation as a test to detect drug allergy reactions. A second generation BAPAD dendrimer ...
      • Presentación de Grupos G5: Fijación de Dendrímeros Antigénicos en superficies para determinación de IgE 

        Perez-Inestrosa, Ezequiel (2016-02-15)
        Presentación de Grupos G5: Descripción de las líneas de investigación del Grupo de Málaga. Trabajos en los que se centra. Facilidades de que dispone
      • Pt(II)-dendrimers as bio-imaging marker for bacteria in two-photon excitation microscopy 

        Vida-Pol, Yolanda; Molina, Noemi; Cnudde, Marvin; Guadix, Juan Antonio; Perez-Pomares, Jose Maria; [et al.] (2019-07-25)
        The use of luminescent markers based on metal complexes in two-photon excitation microscopy techniques are of great interest in the field of bioimaging. However, despite the excellent luminescent properties of Pt(II) ...
      • RGD peptide on Dendrimer surfaces Affects Mesenchymal Stem Cells Adhesion 

        Vida-Pol, Yolanda; Molina, Noemi; Collado, Daniel; Najera-Albendin, Francisco; Lagunas, Anna; [et al.] (2016-04-07)
        Mesenchymal stem cells (MSCs) are promising candidates for a range of tissue regeneration applications. Adequate scaffolds are necessary for their application in vivo, where interactions between cells and the surface ...
      • RGD-dendritic structures on titanium alloy. Influence in the relationship between bone cells and the metal surface 

        Molina, Noemí; González-Luque, Ana; Becerra-Ratia, Jose; Santos-Ruiz, Leonor; Vida-Pol, Yolanda; [et al.] (2019-09-18)
        Prosthetic implants are used in surgical procedures to replace a joint (hip or knee) allowing the functional recovery of the patient. Prostheses are usually made of titanium alloys. However, the lack of chemical and ...
      • Sistema fluorescentes multifotónicos con aplicaciones en bioimagen 

        Collado, Daniel; Perez-Inestrosa, Ezequiel; Vida-Pol, Yolanda; Najera-Albendin, Francisco; Ramon, Patricia; [et al.] (2013-09-20)
        Los colorantes y las sondas fluorescentes son componentes clave en el estudio de muestras biológicas mediante microscopía de fluorescencia. Mientras que muchos colorantes fluorescentes disponibles comercialmente han sido ...
      • Spontaneous [2+2] macrocyclization trhough dynamic covalent aminal bonds 

        Ruiz-Sánchez, Antonio Jesús; Carbajo, Daniel; Najera-Albendin, Francisco; Alfonso, Ignacio; Perez-de-Inestrosa-Villatoro, Ezequiel (2022-06)
        Aminals are characterized by the connectivity of two amino groups to the same carbon atom, being the nitrogenated equivalent of acetals. Unlike acetals, aminals have been slightly underexplored in dynamic covalent chemistry ...
      • Study and characterization of modified silicon surfaces with organic molecules 

        Valpuesta-Fernandez, Maria; Sánchez-Molina, María; Lucena-Serrano, Ana; Contreras-Cáceres, Rafael; López-Romero, Juan Manuel; [et al.] (2016-10-14)
        Nanostructured thin films and subsequent biofunctionalization of silicon substrates are essential for the development of biosensors devices. The formation of organic monolayers on silicon substrates via Si-C bound allows ...
      • Syntehsis and use of dendrimeric structures as a tool in biomedicine 

        Perez-Inestrosa, Ezequiel; Vida-Pol, Yolanda; Molina, Noemi; Morgado, Anjara; Najera-Albendin, Francisco (2019-10-28)
        Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density ...
      • Synthesis and applications in biomedicine of new dendrimeric structures 

        Perez-Inestrosa, Ezequiel (2017-06-20)
        Specific cell interactions of surfaces grafted dendrimers have been applied to the study of cell adhesion. We have studied also the application of dendrimer-based uneven nanopatterns to evaluate the local RGD surface density ...
      • Synthesis and biological activity of a new class of antitumor cyclopeptides based on the solomonamides 

        Cheng-Sánchez, Iván; Carrillo, Paloma; Martínez-Poveda, Beatriz; Quesada, Ana R.; Medina, Miguel Ángel; [et al.] (2018-10-15)
        Solomonamides A (1) and B (2) are novel natural products recently isolated from the marine sponge Theonella swinhoei [1]. Preliminary structural studies revealed an unprecedented cyclic peptide type structure. Interestingly, ...
      • Synthesis and Biological Evaluation of Depudecin Analogues 

        Cheng-Sánchez, Iván; Carrillo, Paloma; García-Ruiz, Cristina; Martínez-Poveda, Beatriz; Quesada, Ana R.; [et al.] (2019-09-18)
        (-)-Depudecin (1) (Figure 1), isolated from the culture broths of the fungus Alternaria brassicicola,1 and later, from the weed pathogen Nimbya scirpicola,2 has been identified as a selective inhibitor of histone deacetylases ...
      • Synthesis and Biomedical aplications of BAPAD: Bisaminoalkylpolyamide Dendrimers 

        Perez-Inestrosa, Ezequiel; Ruiz-Sanchez, Antonio Jesus; Vida-Pol, Yolanda; Collado, Daniel; Najera-Albendin, Francisco; [et al.] (2014-02-06)
        A new class of Dendrimeric Systems (Dendrimers and Dendrons) and the study of their properties in molecular recognition processes are presented. These Dendrimers (BAPAD: BisAminoalkylPolyAmideDendrimers), are designed to ...
      • Synthesis and study of biological activity of tetrahydro-1H-[3]-benzazepines 

        Lucena-Serrano, Ana; Lucena-Serrano, Cristina; López-Romero, Juan Manuel; Díaz, Amelia; Valpuesta-Fernandez, Maria (2017-07-20)
        The 3-Benzazepines are an important class of compounds in drug discovery due to their biological activity such as analgesic, antihypertensive or anticancer properties as well as dopaminergic or antidopaminergic activity. ...
      • Synthesis of bioactive compounds. Studies of their attachment to nanoparticles 

        Lucena-Serrano, Cristina; Lucena-Serrano, Ana; López-Romero, Juan Manuel; Díaz, Amelia; Valpuesta-Fernandez, Maria (2017-07-20)
        The 1-aryl tetrahydroisoquinolines have attracted great attention in medicinal chemistry due to their biological activity. These compounds present antitumor, anti-HIV and antibacterial activities. Several analogues of ...
      • Synthesis of fluorescent BAPAD dendrimeric structrures for biomedical applications 

        Mesa-Antunez, Pablo; Collado, Daniel; Najera-Albendin, Francisco; Perez-Inestrosa, Ezequiel (2014-02-03)
        In this work, we present the synthesis and characterization of BAPAD1 fluorescent Dendrimeric-Antigens (DeAn), to study the dendritic cell maturation as a test to detect drug allergy reactions. Recently our research group ...
      • Synthesis of fluorescent dendrimeric antigen efficiently internalized by human dendritic cells 

        Mesa-Antunez, Pablo; Collado, Daniel; Vida-Pol, Yolanda; Najera-Albendin, Francisco; Fernandez-Duarte, Tahia Diana; [et al.] (Servicio de Publicaciones de la Universidad de Huelva, 2016)
        A new fluorescent dendrimeric antigen (DeAn) based on a dendron with amoxicilloyl terminal groups has been synthetized. The synthesis implies a novel class of all-aliphatic polyamide dendrimer (BisAminoalkylPolyAmide ...
      • Synthesis of fused tetrazolo iminosugars from azido monosaccharide derivatives 

        Pino-Gonzalez, Maria Soledad (Universidad de la Rioja, 2014)
        Synthesis of fused tetrazolo iminosugars from azido monosaccharide derivatives
        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA
        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA
         

         

        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA
        REPOSITORIO INSTITUCIONAL UNIVERSIDAD DE MÁLAGA