ListarQO - Contribuciones a congresos científicos por tema "Antitumor Agents"
Mostrando ítems 1-3 de 3
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New Approaches to Oxirane Containing Natural Products: Stereoselective Total Synthesis of the Antitumor Agents Gummiferol and Depudecin
García-Ruiz, María Cristina; Sarabia-García, Francisco Ramón
(2015-07-30)
La comunicación presenta la síntesis total de productos naturales con actividad antitumoral caracterizados estructuralmente por la presencia de anillos de oxirano. Para ello se empleó una nueva metodología de epoxidación ... -
Synthesis of New Analogues of the Bengamides: Peptidyl Bengamides and Molecular Probes
Aguera-Suárez, Ana María; Porras Alcalá, Cristina; Guerrero Vásquez, Guillermo A.; Cheng-Sánchez, Iván; Sarabia-García, Francisco Ramón (2017-07-20)
Isolated from sponges of the Jaspidae family, first members where discovered in 1986. The bengamides represent an interesting and unprecedented family of natural products that displayed striking antitumor activities [1]. ... -
Total synthesis of depudecin and analogues via an olefin cross-metathesis based strategy
Cheng-Sánchez, Iván; Sarabia-García, Francisco Ramón (2017-07-20)
(-)-Depudecin (1), isolated from the culture broths of the fungus Alternaria brassicicola [1], has been identified as a selective inhibitor of histone deacetylases (HDAC) with an IC50 in the low μM range. In contrast to ...