Listar QO - Contribuciones a congresos científicos por título
Mostrando ítems 1-20 de 45
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Aminonaphtamiline-squaraine dyad: photophysical properties and bioimaging application
(2018-09-19)Squaraines is an important part of the cyanine family which have high extinction coefficients, sharp absorption bands, and intense fluorescence spectra in the red and near infrared region in solution.[1] The unique electronic ... -
Comparative study of dopaminergic activity of tetrahydro-1H-[3]-benzazepines and their precursors
(2016-10-14)The discovery of the tetrahydro-1H-[3]-benzazepine SCH23390 [1], represented one of the most important advances in the study of dopaminergic receptors due to their behavior as a selective D1 receptor antagonist. The high ... -
Dendrimers-modified solid supports: towards nanostructures materials for clinical diagnostic
(2013-09-25)The design and synthesis of new materials for biomedical applications is a high-priority research topic in a number of biomedical areas. The rapid development of nanotechnology over the past few decades has created wide ... -
Design and synthesis of new molecules based on indolium derivatives for two-photon absorption bioimaging applications
(2018-11-15)Bioimaging is the visualization of biological processes in real time, interfering as less as possible with these and using non-invasive methods. Among others, fluorescence methods have acquired a very important role in ... -
Design of multi-haptenized dendrimeric-antigens for in vitro IgE recognition
(2014-06-12)Reactions mediated by the Immunoglobulin E (IgE) involved a high number of allergic drug responses, ranging from simple skin symptoms to anaphylactic shock.1 In order to emulate the recognition process working in vivo, ... -
Detecting hydroxyl radical with a new two-photon fluorescent probe in living cells
(Real Sociedad Española de Química, 2018-06-20)Reactive oxygen species (ROS) are known to be involved in the onset and development of multiple diseases, including cancer, cardiovascular diseases, neurodegenerative diseases and diabetes among others. Generation of ROS ... -
Diastereoselective synthesis of chiral amines by imines alkylation
(2013-10-03)En esta comunicación se aborda la síntesis de aminas quirales utilizando como agente alquilante trietilborano. -
Diseño y síntesis de nuevos dendrímeros
(2018-03-06)Los dendrímeros son excelentes plataformas multifuncionales para una gran cantidad de diferentes aplicaciones. En particular, el desarrollo de nanoestructuras moleculares multivalentes, con tamaño y forma bien definida, ... -
Diseño y síntesis de nuevos dendrímeros y dendrones. Aplicaciones en regeneración tisular
(2018-03-06)Los dendrímeros han generado un enorme interés debido a su particular estructura ramificada y su multivalencia. La extensa investigación que se ha llevado a cabo sobre este tipo de macromoléculas ha demostrado la naturaleza ... -
Diseño y síntesis de nuevos dendrones para aplicaciones biomédicas
(2018-03-06)Los dendrímeros han sido empleados en una gran variedad de aplicaciones, entre las que destacan las del campo de la biomedicina. Estas macromoléculas multivalentes ofrecen la posibilidad de incorporar múltiples funcionalidades ... -
Energy transfer in Aminonaphthalimide-BODIPY dyads upon one and two photons excitation
(2014-07-03)BODIPY dyes are nowadays widely commercialized chromophores that have attracted immense interest as versatile tools in biological chemistry [1]. However, the generally very small Stokes shifts of BODIPY dyes may cause ... -
Fijación de dendrímeros antigénicos en superficies para determinación de IgE
(2016-02-15)Actualmente, el diseño de nuevos materiales con potenciales aplicaciones biomédicas es de gran importancia , sobre todo para su uso directo en diagnóstico clínico . En particular, los dispositivos que ... -
Hybrid pH-Responsive Au@p4VP Microgels as Platform for Selective SERS Analysis
(2017-09-21)We present the synthesis a of pH-responsive core@shell hybrid microgel. This colloidal system is formed by a 55 nm Au core individually covered by a polymeric pH-sensitive shell of poly(4-vinylpyridine), that we denote as ... -
Intramolecular [3+2] cycloaddition of azido-unsaturated esters derived of monosaccharides
(2013-11-05)Iminosugars have been shown to be very potent inhibitors of glycosidases and glycolsyltransferases. Due to their ability to resemble the transition states of the sugars involved in these processes, a variety of m onocyclic ... -
Intramolecular [3+2] Cycloaddition of Fused Azolo-Azepanes from Azido Monosaccharides Derivatives
(Centro Investigaciones Biológicas, 2016)Síntesis de bicíclicos compuestos empleando epoxiamidas como material de partida. Obtención de tetrazolo azepanos con posible actividad biológica. -
Lipid and Janus nanoparticles for active delivery
(2014-06-12)The following synthesis is based on the paper „Production of large quantities of „Janus“ nanoparticles using wax-in-water emulsions“ published by Ravaine et al.[1]In two beakers, 0.2 g of the synthesized silica particles ... -
Managing with (fluorescent)-biomimetic dendrimers
(2017-06-30)Dendrimers that are modified through their peripheral groups have been employed for many biomedical purposes. Diagnosis via specific interactions with target proteins is one of the objectives that has been given more ... -
New Approaches to Oxirane Containing Natural Products: Stereoselective Total Synthesis of the Antitumor Agents Gummiferol and Depudecin
(2015-07-30)La comunicación presenta la síntesis total de productos naturales con actividad antitumoral caracterizados estructuralmente por la presencia de anillos de oxirano. Para ello se empleó una nueva metodología de epoxidación ... -
New bodipy dyads for two-photons fluorescence imaging in cells
(2016-09-13)Fluorescent probes are essential tools for studying biological systems. The last decade has witnessed particular interest in the development of two-photon excitable probes, due to their advantageous features in tissue ... -
New indolium fluorofores for two-photon absortion (2PA) bioimaging applications
(2016)The development of organic materials with 2PA has attracted intensive attention in the past two decades [1]. In two-photon bio-imaging applications the design of the chromophore requires to have a good cross-section (σ2PA) ...