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dc.contributor.authorÁlvarez-Torres, Daniel
dc.contributor.authorPodadera, Ana Maria
dc.contributor.authorGarcía-Rosado, Esther 
dc.contributor.authorCollet, Bertrand
dc.contributor.authorBejar-Alvarado, Julia 
dc.contributor.authorAlonso-Sanchez, Maria del Carmen 
dc.date.accessioned2013-12-05T09:04:25Z
dc.date.available2013-12-05T09:04:25Z
dc.date.issued2013
dc.identifier.urihttp://hdl.handle.net/10630/6745
dc.description.abstractTransfected RTG-2 cells infected with VHSV showed significant induction of the luciferase reporter gene, compared to the control non-infected cells, at 24, 48 and 72 h post infection (p.i.). The maximum expression was recorded at 72 h p.i. (2.25 folds compared to the control cells). In these cells, the infection with IPNV and EHNV did not result in the luciferase expression at any time tested. In transfected CHSE-214 cells, EHNV stimulated luciferase expression at 24 h p.i. (2.17 folds compared to the control cells), whereas cells infected with IPNV and VHSV did not show luciferase activity at any time. The lack of induction of the SsMx promoter after VHSV infection in CHSE-214 cells, as well as after EHNV infection in RTG-2 cells may be caused by viral IFN-suppression mechanisms, as has been demonstrated for IPNV in previous studies. Furthermore, the different induction of the SsMx promoter observed in RTG-2 and CHSE-214 cells after infection with the same virus indicates that cellular specific factors are involved in the IFN-signaling response. Therefore, the use of two different cellular systems might be an interesting approach to identify such cellular factors.es_ES
dc.description.sponsorshipUNIVERSIDAD DE MÁLAGA. CAMPUS DE EXCELENCIA INTERNACIONAL ANDALUCÍA TECHes_ES
dc.language.isoenges_ES
dc.publisherEAFPes_ES
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectVirología - Investigaciónes_ES
dc.titleDifferences in the viral induction of the senegalese sole Mx protein in RTG-2 and CHSE-214 cellses_ES
dc.typeinfo:eu-repo/semantics/conferenceObjectes_ES
dc.centroFacultad de Cienciases_ES
dc.relation.eventtitle16th international conference on diseases of fish and shellfishes_ES
dc.relation.eventplaceTampere, Finlandiaes_ES
dc.relation.eventdateSeptiembre 2013es_ES


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