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Listar por autor "Mejías-Ortega, Marina"
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Coexistance of different myeloid populations in the frontal cortex of alzheimer's disease patients
Mejías-Ortega, Marina; Sánchez-Mejías, Elisabet; Nuñez-Diaz, Cristina; Trujillo-Estrada, Laura Isabel
; Sánchez-Varo, Raquel María
; Dávila-Cansino, José Carlos
; Dávila-Cansino, José Carlos
; Gutiérrez-Pérez, Antonia
[et al.] (2020-12-16)
Parenchymal microglia, the brain-resident immune cells capable of responding to damage and disease, has been postulated as a critical factor in the Alzheimer´s disease (AD) progression. Apart from microglia, CNS macrophages, ... -
Involvement of different aβ-associated myeloid populations in the human alzheimer’s brain
Mejías-Ortega, Marina; Sánchez-Mejías, Elisabet; Muñoz-Castro, Clara; Trujillo-Estrada, Laura Isabel
; Vizuete, María Luisa; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia
[et al.] (2022)
Parenchymal microglia, the brain-resident immune cells, have been postulated as a critical factor in Alzheimer´s disease (AD) since the identification of genetic risk factors related to their functions. Though the role of ... -
Mitochondrial ultrastructural defects in reactive astrocytes of Alzheimer's mice hippocampus.
Trujillo-Estrada, Laura Isabel; López Oliva, Elba; Fernández-Valenzuela, Juan José; Sánchez-Mejías, Elisabet
; Mejías-Ortega, Marina; Vizuete, María Luisa; Vitorica Ferrández, Javier; Gutiérrez-Pérez, Antonia
[et al.] (2023)
Alzheimer's disease (AD) is a complex neurodegenerative condition that causes progressive memory loss and dementia. In AD brains astrocyte become reactive potentially contributing to cognitive decline. Astrocyte reactivity ... -
Transgenic Mouse Models of Alzheimer’s Disease: An Integrative Analysis
Sánchez-Varo, Raquel María; Mejías-Ortega, Marina; Fernández-Valenzuela, Juan José; Núñez Díaz, Cristina; Cáceres Palomo, Laura; Vegas-Gómez, Laura; Sánchez Mejías, Elisabeth; Trujillo-Estrada, Laura Isabel
; Moreno González, Inés; García-León, Juan Antonio
; Vizuete, María Luisa; Vitorica Ferrández, Javier; Baglietto-Vargas, David; Gutiérrez-Pérez, Antonia
[et al.] (IOAP-MPDI, 2022-05-12)
Alzheimer’s disease (AD) constitutes the most prominent form of dementia among elderly individuals worldwide. Disease modeling using murine transgenic mice was first initiated thanks to the discovery of heritable mutations ...