Listar por autor "Robles-Diaz, Maria Mercedes"
Mostrando ítems 1-10 de 10
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Clinical characteristics and outcome of drug-induced liver injury in the older patients: from the young-old to the oldest-old
Weersink, Rianne A.; Alvarez-Alvarez, Ismael; Medina-Caliz, Inmaculada
; Sanabria-Cabrera, Judith Adriana; Robles-Diaz, Maria Mercedes; Ortega-Alonso, Aida; García-Cortés, Miren; Bonilla, Elvira; Niu, Hao; Soriano, German; Jimenez-Perez, Miguel; Hallal, Hacibe; Blanco, Sonia; Kaplowitz, Neil; Lucena-González, María Isabel; Andrade-Bellido, Raul Jesus[et al.] (Wiley, 2020-11-11)
Old patients with hepatotoxicity have been scarcely studied in idiosyncratic drug-induced liver injury (DILI) cohorts. We sought for the distinctive characteristics of DILI in older patients across age groups. A total of ... -
Comprehensive analysis and insights gained from long-term experience of the Spanish DILI Registry
Stephens, Camilla; Robles-Diaz, Maria Mercedes; Medina-Caliz, Inmaculada; García-Cortés, Miren; Ortega-Alonso, Aida; Sanabria-Cabrera, Judith Adriana; González-Jiménez, Andrés; Alvarez-Alvarez, Ismael; Slim, Mahmoud; Jimenez-Perez, Miguel; Gonzalez-Grande, Rocio; Fernandez, M Carmen; Casado, Marta; Soriano, German; Roman, Eva; Hallal, Hacibe; Romero-Gomez, Manuel; Castiella, Agustin; Conde, Isabel; Prieto, Martin; Moreno-Planas, José María; Giraldez, Alvaro; Moreno-Sanfiel, J Miguel; Kaplowitz, Neil; Lucena-González, María Isabel; Andrade-Bellido, Raul Jesus[et al.] (Elsevier, 2021-02-01)
Background & aims: Prospective drug-induced liver injury (DILI) registries are important sources of information on idiosyncratic DILI. We aimed to present a comprehensive analysis of 843 patients with DILI enrolled into ... -
Evaluation of diagnostic and prognostic candidate biomarkers in drug-induced liver injury vs. other forms of acute liver damage
Cueto-Sánchez, Alejandro; Niu, Hao; Álvarez-Álvarez, Ismael; López-Longarela, Bárbara; Del Campo-Herrera, Enrique; Ortega-Alonso, Aida; García-Cortés, Miren; Pinazo-Bandera, José; Sanabria-Cabrera, Judith Adriana; Díaz-Monchón, Juan José; Lucena-González, María Isabel; Andrade-Bellido, Raul Jesus; Stephens, Camilla; Robles-Diaz, Maria Mercedes[et al.] (Wiley, 2023)
Aims Detection and characterization of idiosyncratic drug-induced liver injury (DILI) currently rely on standard liver tests, which are suboptimal in terms of specificity, sensitivity and prognosis. Therefore, DILI diagnosis ... -
Incidence and prevalence of acute hepatitis E virus infection in patients with suspected Drug-Induced Liver Injury in the Spanish DILI Registry
Sanabria-Cabrera, Judith Adriana; Sanjuan-Jimenez, Rocio; Clavijo-Frutos, Encarnacion; Medina-Caliz, Inmaculada; González-Jiménez, Andrés; García-Cortés, Miren; Ortega-Alonso, Aida; Jimenez-Perez, Miguel; Gonzalez-Grande, Rocio; Stephens, Camilla; Robles-Diaz, Maria Mercedes; Lucena-González, María Isabel; Andrade-Bellido, Raul Jesus[et al.] (2020)
Background and Aims: Drug-induced liver injury (DILI) presents with a wide phenotypic spectrum requiring an extensive differential diagnosis. Hepatitis E virus (HEV) is not systematically ruled out during acute hepatitis ... -
Infección aguda por el virus de la hepatitis E en pacientes con sospecha de daño hepático tóxico en el Spanish DILI Registry
Sanabria-Cabrera, Judith Adriana (UMA Editorial, 2020-09-30)
Antecedentes y objetivos: el daño hepático inducido por fármacos también denominado DILI (Drug Induced Liver Injury), se presenta con un amplio espectro fenotípico que requiere un diagnóstico diferencial extenso. El virus ... -
Lymphocyte Profile and Immune Checkpoint Expression in Drug-Induced Liver Injury: An Immunophenotyping Study
Cueto-Sanchez, Alejandro; Niu, Hao; Del Campo-Herrera, Enrique; Robles-Diaz, Maria Mercedes; Sanabria-Cabrera, Judith Adriana; Ortega-Alonso, Aida; García-Cortés, Miren; Gonzalez-Grande, Rocio; Jimenez-Perez, Miguel; Ruiz-Cabello, Francisco; Andrade-Bellido, Raul Jesus; Lucena-González, María Isabel[et al.] (Wiley, 2021-09-20)
The identification of specific HLA risk alleles in drug-induced liver injury (DILI) points toward an important role of the adaptive immune system in DILI development. In this study, we aimed to corroborate the role of an ... -
Microbiota diversity in nonalcoholic fatty liver disease and in drug-induced liver injury
Rodriguez-Diaz, Cristina; Taminiau, Bernard; García-García, Alberto; Cueto-Sanchez, Alejandro; Robles-Diaz, Maria Mercedes; Ortega-Alonso, Aida; Martín-Reyes, Flores; Daube, Georges; Sanabria-Cabrera, Judith Adriana; Jimenez-Perez, Miguel; Lucena-González, María Isabel; Andrade-Bellido, Raul Jesus; García Fuentes, Eduardo; García-Cortés, Miren[et al.] (Elsevier, 2022-08)
The gut microbiota could play a significant role in the progression of nonalcoholic fatty liver disease (NAFLD); however, its relevance in drug-induced liver injury (DILI) remains unexplored. Since the two hepatic disorders ... -
Potential benefit and lack of serious risk from corticosteroids in drug-induced liver injury: an international, multicentre, propensity score-matched analysis
Niu, Hao; Ma, Jiayi; Medina-Caliz, Inmaculada; Robles-Diaz, Maria Mercedes; Bonilla-Toyos, Elvira; Ghabril, Marwan; Lucena-González, María Isabel; Álvarez-Álvarez, Ismael; Andrade-Bellido, Raul Jesus[et al.] (Wiley, 2022-12-22)
Background: The use of corticosteroids to treat patients with idiosyncratic drug-induced liver injury (DILI) relies on empirical clinical decisions. Aim: To investigate the relationship between corticosteroids and ... -
Prevention and management of idiosyncratic drug-induced liver injury: Systematic review and meta-analysis of randomised clinical trials
Niu, Hao; Sanabria-Cabrera, Judith Adriana; Alvarez-Alvarez, Ismael; Robles-Diaz, Maria Mercedes; Stankeviciute, Simona; Aithal, Guruprasad P.; Bjornsson, Einar S.; Andrade-Bellido, Raul Jesus; Lucena-González, María Isabel; Sanabria-Cabrera, Judith Adriana[et al.] (Elsevier, 2021-02)
Conducting randomised clinical trials (RCTs) in idiosyncratic drug-induced liver injury (DILI) is challenging. This systematic review aims to summarise the design and findings of RCTs in the prevention and management of ... -
Serious liver injury induced by Nimesulide: an international collaboration study reporting 57 cases
Bessone, Fernando; Hernandez, Nelia; Mendizabal, Manuel; Ridruejo, Ezequiel; Gualano, Gisela; Fassio, Eduardo; Peralta, Mirta; Fainboim, Hugo; Anders, Margarita; Tanno, Hugo; Tanno, Federico; Parana, Raymundo; Medina-Caliz, Inmaculada; Robles-Diaz, Maria Mercedes; Alvarez-Alvarez, Ismael; Niu, Hao; Stephens, Camilla; Colombato, Luis; Arrese, Marco; Reggiardo, Maria Virginia; Ono, Suzane Kioko; Carrilho, Flair; Lucena-González, María Isabel; Andrade-Bellido, Raul Jesus[et al.] (Springer, 2021-03-24)
Nimesulide is a non-steroidal anti-inflammatory drug still marketed in many countries. We aim to analyze the clinical phenotype, outcome, and histological features of nimesulide-induced liver injury (nimesulide-DILI). We ...