Farmacología y Pediatría - (FP): Envíos recientes
Mostrando ítems 21-40 de 245
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Hepatic safety of atypical antipsychotics: current evidence and future directions
(Springer, ADIS INT LTD, 2016-10)The newer atypical antipsychotic agents (AAPs) represent an attractive therapeutic option for a wide range of psychotic disorders, including schizophrenia and bipolar mania, because of the reduced risk of disabling ... -
Role of chemical structures and the 1331T>C bile salt export pump polymorphism in idiosyncratic drug-induced liver injury
(WILEY, 2013-04)Background & aims: Several pharmaceutical compounds have been shown to exert inhibitory effects on the bile salt export pump (BSEP) encoded by the ABCB11 gene. We analysed the combined effect on drug-induced liver injury ... -
Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet
(Elsevier, 2023-12-28)In the current article the aims for a constructive way forward in Drug-Induced Liver Injury (DILI) are to highlight the most important priorities in research and clinical science, therefore supporting a more informed, ... -
Genetic polymorphisms of CYP2C9 and CYP2C19 are not related to drug-induced idiosyncratic liver injury (DILI)
(2007-01-29)Background and purpose: The general view on the pathogenesis of drug-induced idiosyncratic liver injury (DILI) is that parent compounds are rendered hepatotoxic by metabolism, mainly by cytochrome (CYP) 450, although other ... -
Herbal and dietary supplements-induced liver injury in Latin America: Experience from the LATINDILI Network
(Elsevier, 2022)Background: Herbal and dietary supplements (HDS) consumption, a growing cause of hepatotoxicity, is a common practice among Latin-American populations. Objectives: To evaluate clinical, laboratory features and outcome ... -
Análisis de los factores de riesgo para el desarrollo y la progresión de la retinopatía del prematuro en el Hospital Materno Infantil de Málaga
(UMA Editorial, 2023-06-25)El objetivo de esta tesis doctoral es determinar la incidencia y los factores de riesgo asociados con el desarrollo y la progresión de la Retinopatía del Prematuro (ROP). Para ello, se incluyeron 452 prematuros con criterios ... -
Prior drug allergies are associated with worse outcome in patients with idiosyncratic drug-induced liver injury: A machine learning approach for risk stratification
(Elsevier, 2023-12-08)The impact of prior drug allergies (PDA) on the clinical features and outcomes of patients who develop idiosyncratic drug-induced liver injury (DILI) is largely unknown. We aimed to assess the clinical presentation and ... -
Approach to patients with diabetes and obesity in primary care
(Elsevier, 2023-10-17)Aims: The aim of this study is to analyse the effect of pharmacological and non-pharmacological treatment on weight control in patients with diabetes and obesity. Design: Epidemiological, descr ... -
Characterization of drug-induced liver injury associated with drug reaction with eosinophilia and systemic symptoms in two prospective DILI registries
(Springer Nature, 2023-12-05)Idiosyncratic drug-induced liver injury (DILI) associated with drug reactions with eosinophilia and systemic symptoms (DRESS) is poorly characterized among patients of Western countries. We aimed to comprehensively assess ... -
Effectiveness of an educational intervention about inhalation technique in healthcare professionals in primary care: a cluster randomized trial
(Frontiers, 2023)Incorrect inhalation technique (IT) is an important issue for COPD patients and healthcare professionals. Studies in which counseling is carried out with healthcare professionals beforehand so that they can properly educate ... -
Papel del sistema inmune y la microbiota intestinal en el daño hepático inducido por fármacos. Búsqueda de nuevos biomarcadores.
(UMA Editorial, 2023)El daño hepático inducido por fármacos (DILI) es una condición infrecuente, pero puede tener consecuencias graves para los pacientes, ya que puede resultar en fallo hepático fulminante. El mecanismo subyacente de DILI no ... -
Educación nutricional precoz en la prevención de la obesidad infantil.
(UMA Editorial, 2023)La infancia temprana constituye un periodo crítico para la prevención de la obesidad en etapas posteriores. Este estudio evalúa la efectividad de una intervención educacional para prevenir la obesidad en colegios de ... -
Atención farmacéutica en pacientes ostomizados
(2023)Objetivo. Se analiza el alcance que la atención farmacéutica (AF) supone en pacientes ostomizados incluyendo el análisis de disponibilidad a pagar por el paciente en caso de recibir ayuda en la oficina de farmacia ... -
Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report
(Elsevier, 2023)Drug-induced liver injury (DILI) can mimic almost all other liver disorders. A phenotype increasingly ascribed to drugs is autoimmune-like hepatitis (ALH). This article summarises the major topics discussed at a joint ... -
Efecto de 3,4-dihidroxifenilglicol, polifenol del aceite de oliva virgen extra, en la nefropatía diabética experimental.
(2023)Objetivo: El objetivo de este estudio fue analizar el efecto nefroprotector de 3',4'-dihidroxifenilglicol (DHPG), un compuesto polifenólico del aceite de oliva virgen extra (AOVE), sobre las lesiones renales en un modelo ... -
Sinergismo entre 3,4-dihidroxifenilglicol e hidroxitirosol sobre biomarcadores cardiovasculares, estrés oxidativo y nitrosativo en un modelo experimental de Diabetes Mellitus tipo 1.
(2023)Resumen Póster: Objetivo El objetivo de este estudio fue evaluar el efecto sinérgico de dos polifenoles del aceite de oliva virgen extra, 3,4,-dihidroxifenilglicol (DHPG) e hidroxitirosol (HT), sobre biomarcadores ... -
Efecto del factor de crecimiento insulínico tipo II sobre el daño oxidativo-mitocondrial y neuronal inducido por MPP+ y corticosterona en neuronas dopaminérgicas en cultivo
(UMA Editorial, 2023)La Enfermedad de Parkinson (EP), es el trastorno de movimiento más frecuente, siendo la segunda causa de enfermedad neurodegenerativa en todo el mundo. Se caracteriza por la aparición progresiva de síntomas motores y ... -
Overweight and Obesity: its Impact on Foot Type, Flexibility, Foot Strength, Plantar Pressure and Stability in Children from 5 to 10 Years of Age: Descriptive Observational Study.
(MDPI, 2023-04-07)Background: Overweight (OW) and childhood obesity (OB) may cause foot problems and affect one’s ability to perform physical activities. The study aimed to analyze the differences in descriptive characteristics, foot type, ... -
Clinical presentation, causative drugs and outcome of patients with autoimmune features in two prospective DILI registries
(Wiley, 2023)Background & aims: Idiosyncratic drug-induced liver injury (DILI) with autoimmune features is a liver condition with laboratory and histological characteristics similar to those of idiopathic autoimmune hepatitis (AIH), ... -
Células mesenquimales troncales en el tratamiento de la enfermedad injerto contra huésped y experiencia en Andalucía.
(UMA Editorial, 2023)1) Antecedentes y objetivos: La enfermedad de injerto contra huésped es una patología grave que puede desencadenarse después de recibir un trasplante de progenitores hematopoyéticos alogénicos. La incidencia de la enfermedad ...